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Recent Developments in the Endoscopic Treatment of Patients with Peptic Ulcer Bleeding

Jang JY

Peptic ulcer bleeding is an internal medical emergency. Endoscopic hemostasis has been shown to improve the survival rate of patients with peptic ulcer bleeding. Although the established hemostatic modalities, including...
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Diagnosis and Management of Peptic Ulcer Bleeding

Sung JK

Despite the generally declining trend in the incidence of peptic ulcers, peptic ulcer bleeding remains a prevalent and clinically significant condition. Additionally, despite the development of therapeutic endoscopy and acid-suppressive...
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Complications and Management of Peptic Ulcer Disease

Bang CS, Baik GH

Despite the improvement of medical managements of peptic ulcer and decline of Helicobacter pylori infection, complications of peptic ulcer are still prevalent in clinical practice. This is because of the...
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Pharmacological Therapy of Peptic Ulcer

Oh JH

Peptic ulcer disease is one of the most commonly encountered diseases. Despite the decrease of Helicobacter pylori infection, the use of aspirin and non-steroidal anti-inflammatory drugs has increased in recent...
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Endoscopic Hemostatic Treatment of Peptic Ulcer Bleeding

Choe YH, Park JC

Peptic ulcer bleeding is a common complication of peptic ulcer disease and the most common cause of upper gastrointestinal bleeding. Despite advances in drug usage and endoscopic modalities, no significant...
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Gastric Submucosal Hematoma after Endoscopic Hemostasis in Patient with Dual Antiplatelet Therapy

Kim T, Kim HU, Song HJ

Intramural hematoma of the gastrointestinal tract is uncommon, with the majority being localized to the esophagus or duodenum. Hematoma of the gastric wall is extremely rare and caused by coagulopathy,...
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Risk Factors for Rebleeding after Initial Endoscopic Hemostasis in Patients with Peptic Ulcer Hemorrhage

Joo SY, Joo YE, Noh DY, Park SY, Lee WS, Park CH, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

  • KMID: 1973361
  • Chonnam Med J.
  • 2004 Jun;40(2):79-86.
Rebleeding after initial endoscopic hemostasis in patients with peptic ulcer hemorrhage has been reported in 20~30%. Identification of patients who are at high risk for rebleeding would be expected to...
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Management of Non-Variceal Upper Gastrointestinal Bleeding

Kim SY, Hyun JJ, Jung SW, Lee SW

  • KMID: 2134511
  • Clin Endosc.
  • 2012 Sep;45(3):220-223.
Upper gastrointestinal bleeding (UGIB) is a critical condition that demands a quick and effective medical management. Non-variceal UGIB, especially peptic ulcer bleeding is the most significant cause. Appropriate assessment and...
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Efficacy of ethanol and hypertonic saline-epinephrine injection therapy for peptic ulcer bleeding

Ahn JY, Kim JG, Kim JW, Kim SJ, Han SP, Kim HJ, Do JH, Chang SK, Park SM

  • KMID: 1984638
  • Korean J Med.
  • 2005 Jul;69(1):21-29.
BACKGROUND: One of simple, inexpensive, readily available treatments for treating peptic ulcer bleeding is injection of the lesion with a sclerosing substance such as ethanol and hypertonic saline-epinephrine. The aim...
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Clinical Usefulness of Rockall Scoring System in Patients with Bleeding Peptic Ulcer-Comparison with Forrest Classification

Oh YJ, Lee JH, Kim KH, Lim YJ, Park JH, Son HJ, Rhee PL, Kim JJ, Rhee JC

  • KMID: 1113319
  • Korean J Gastroenterol.
  • 2004 Aug;44(2):66-70.
BACKGROUND/AIMS: The Rockall risk assessment score was developed to predict the risk of rebleeding and death in patients with upper GI hemorrhage. The validity of this score, however, was...
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Helicobacter pylori Eradication within 120 Days Is Associated with Decreased Complicated Recurrent Peptic Ulcers in Peptic Ulcer Bleeding Patients

Chang SS, Hu HY

BACKGROUND/AIMS: The connection between Helicobacter pylori and complicated peptic ulcer disease in peptic ulcer bleeding (PUB) patients taking nonsteroidal anti-inflammatory drugs has not been established. In this study, we sought...
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Guidelines of Treatment for Bleeding Peptic Ulcer Disease

Chung IK, Lee DH, Kim HU, Sung IK, Kim JH, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association of Gastroenterology

Peptic ulcer (PU) bleeding is the main cause of non-variceal gastrointestinal bleeding. Negative outcomes include re-bleeding and death, and many of the deaths are associated with decompensation of coexisting medical...
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Comparison of Clinical Characteristics and Outcomes between Geriatric and Non-geriatric Patients in Peptic Ulcer Bleeding

Na YJ, Shim KN, Kang MJ, Jung JM, Kim SE, Jung SA, Yoo K, Moon IH

BACKGROUND/AIMS: In geriatric patients with peptic ulcer, the use of NSAID and prevalence of chronic illness have been increased, but the Helicobacter pylori (H. pylori) infected portion decreased. The aim...
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Tissue Plasminogen Activator and Plasminogen Activator Inhibitor Type 1 Gene Polymorphism in Patients with Gastric Ulcer Complicated with Bleeding

Kim HS, Hwang KY, Chung IK, Park SH, Lee MH, Kim SJ, Hong SY

Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) may be involved in the pathogenesis of peptic ulcers through suppression of fibrinolysis. This study was designed to investigate...
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Direct Percutaneous Endoscopic Jejunostomy in a Patient with Previous Subtotal Gastrectomy

Chu HJ, Kim GH, Kang DH, Song GA, Cho M, Yang US

  • KMID: 1929291
  • Korean J Gastrointest Endosc.
  • 2002 Feb;24(2):84-87.
It is generally considered that enteral feeding is superior to parenteral nutritional support. Thus enteral meal should be given whenever patients have proper gastrointestinal function to take enteral feeding. Because...
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A Comparison of the Effect of High-dose Oral and Intravenous Proton Pump Inhibitor on the Prevention of Rebleeding after Endoscopic Treatment of Bleeding Peptic Ulcers

Jang JY, Joo KR, Hwangbo Y, Jeong LI, Choi SY, Jung JH, Chae MJ, Lee SK, Dong SH, Kim HJ, Kim BH, Chang YW, Lee JI, Chang R

  • KMID: 2304841
  • Korean J Gastrointest Endosc.
  • 2006 Jul;33(1):6-11.
BACKGROUND/AIMS: The use of proton pump inhibitor (PPI) prevents rebleeding by elevating the intragastric pH in patients with bleeding peptic ulcers after hemostasis has been achieved. We assessed if high-dose...
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Optimal Operational Definition of Patient with Peptic Ulcer Bleeding for Big Data Analysis Using Combination of Clinical Characteristics in a Secondary General Hospital

Lee JW, Kim HK, Woo YS, Jahng J, Jin YR, Park JH, Kim YS, Jung HY

BACKGROUND/AIMS: Peptic ulcer bleeding (PUB) is the most common cause of upper gastrointestinal bleeding in Korea but there has been no research done using big data. This study evaluates the...
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Comparison between Endoscopic Therapy and Medical Therapy in Peptic Ulcer Patients with Adherent Clot: A Multicenter Prospective Observational Cohort Study

Kim SH, Jung JT, Kwon JG, Kim EY, Lee DW, Jeon SW, Park KS, Lee SH, Park JB, Ha CY, Park YS, Daegu-Gyeongbuk Gastrointestinal Study Group (DGSG)

BACKGROUND/AIMS: The optimal management of bleeding peptic ulcer with adherent clot remains controversial. The purpose of this study was to compare clinical outcome between endoscopic therapy and medical therapy. We...
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What is the best method to diagnose Helicobacter infection in bleeding peptic ulcers?: a prospective trial

Chung IK, Hong SJ, Kim EJ, Cho JY, Kim HS, Park SH, Lee MH, Kim SJ, Shim CS

  • KMID: 759552
  • Korean J Intern Med.
  • 2001 Sep;16(3):147-152.
BACKGROUND: It has been debated which diagnostic test should be preferred for the diagnosis of Helicobacter pylori (HP) in patients with peptic ulcer diseases. Several limitations are reported in bleeding...
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The Influence of Non-steroidal Anti-inflammatory Drugs on Clinical Outcome in Patients with Bleeding Peptic Ulcers

Kim KH, Kim HY, Choi JW, Lee JY, Bae YD, Baek GH, Jang MK, Park JY, Lee JH, Yoo JY

  • KMID: 772860
  • Korean J Gastroenterol.
  • 2005 Nov;46(5):373-380.
BACKGROUND/AIMS: We conducted this study to find the clinical characteristics of ulcer bleeding that occurred in patients who had been taking non-steroidal anti-inflammatory drugs (NSAIDs) and to evaluate the...
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