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Electrical Cellular Physiology in Cochlear Nucleus Using Patch-Clamp Techniques

Jun BC

No abstract available.
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General Anesthetics and Single-Channel Recording

Kim KH, Shin WJ

  • KMID: 1482464
  • Hanyang Med Rev.
  • 2008 Nov;28(4):53-62.
Introduction of patch-clamp techniques allowed an increase in resolution of membrane current recordings. However, the technique was limited by apparent need for direct contact of pipette with cell membrane. Thus,...
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Characterization of Membrane Excitability of Purkinje Cells in Vestibulocerebellum Using Patch Clamp Techniques

Kim CH

Cerebellum is known as a center for sensory/motor coordination and memory storage in motor learning. The vestibular nuclei have extensive afferent and efferent connections with posterior cerebellum which can be...
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The Effect of Papaverine on L-Type Ca2+ Current in Rat Basilar Smooth Muscle Cells

Kim CJ, Han DH, Gwa YG

  • KMID: 1955925
  • J Korean Neurosurg Soc.
  • 2002 Feb;31(2):161-165.
OBJECTIVE: Papaverine has been used to manage vasospasm after subarachnoid hemorrhage. However, its mechanism for cerebrovascular smooth muscle are still not clear. This study was undertaken to investigate the effect...
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The characterization of the increase of membrane conductance after depolarization in single rat adrenal chromaffin cells

Lim W, Kim SJ, Kim J

  • KMID: 2071529
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):95-100.
The conductance change evoked by step depolarization was studied in primarily cultured rat adrenal chromaffin cells using patch-clamp and capacitance measurement techniques. When we applied a depolarizing pulse to a chromaffin cell, the...
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Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats

Jeong HS, Huh HR, Jang MJ, Hong SH, Jang S, Park J, Lee SH, Kim JH, Park JS

  • KMID: 2285323
  • Korean J Physiol Pharmacol.
  • 2006 Jun;10(3):131-135.
Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular...
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Inhibitory Effects of Norepinephrine on the Potassium Current of Rat Medial Vestibular Nuclear Neurons

Jeong HS, Jang MJ, Huang M, Huh HR, Cho KH, Kim BC, Park JS

  • KMID: 1626909
  • J Korean Neurol Assoc.
  • 2005 Jun;23(3):363-367.
BACKGROUND: This study aimed to explore the effects of norepinephrine on the potassium currents of rat medial vestibular nuclear neurons by using the whole-cell patch clamp technique. METHODS: Sprague-Dawley rats...
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Activation of ATP-sensitive potassium channels by the predominant metabolite of isoflurane in rabbit ventricular myocytes

Han J, Kim NR, Kim EY, Kim SJ, Cho KH

  • KMID: 2285237
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):165-175.
Background: Recent in vivo experimental evidence suggests that isoflurane-induced cardioprotection may involve KATP channel activation. However, it was demonstrated that isofluran inhibited KATP channel activities in the inside-out patch mode. To explain this discrepancy,...
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Modulation of the Neuronal Activity of Vestibular Nuclear Neurons by 8-OH-DPAT

Jeong HS, Jang MJ, Huang M, Park JS

  • KMID: 2172336
  • Chonnam Med J.
  • 2005 Apr;41(1):19-24.
This study was aimed to investigate the effects of the 8-hydroxy-2-(di-N-propylamino) tetralin (8-OH- DPAT), a specific 5-HT1A receptor agonist on the spontaneous activity of medial vestibular nuclear neurons of the...
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Analysis of Electrophysiological Change in the Rat LC Nucleus after Salicylic Acid Treatment

Kim SC, Kim SB, Park SY, Jun BH

  • KMID: 2276565
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Feb;49(2):148-152.
BACKGROUND AND OBJECTIVES: The precise mechanism of salicylic acid induced tinnitus has not been clearly identified as yet in spite of wide range of studies undertaken. We looked for the...
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Role of Plasmalogen-derived Lysolipids onthe Pathophysiology of Myocardial Ischemia

Pio LH, Kim JH

  • KMID: 1883693
  • Chonnam Med J.
  • 2007 Dec;43(3):168-176.
To clarify the role of plasmalogen-derived lysolipids on pathophysiology of myocardial ischemia, effects of the lysolipids on the regulation of ATP-sensitive K+ channel (K(ATP) channel) activities were examined in enzymatically...
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The Effect of Tyrosine Kinase Inhibitors on the L-type Calcium Current in Rat Basilar Smooth Muscle Cells

Bai GY, Yang TK, Gwak YG, Kim CJ

  • KMID: 1822236
  • J Korean Neurosurg Soc.
  • 2006 Mar;39(3):215-220.
OBJECTIVE: Tyrosine kinase inhibitors may be useful in the management of cerebral vasospasm. It has not yet been reported whether L-type Ca2+ channels play a role in tyrosine kinase inhibitors-induced...
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Effects of Norepinephrine on the Resting Activity of Medial Vestibular Nuclear Neurons in the Rat

Jeong HS, Huh HR, Huang M, Park JS

  • KMID: 2172335
  • Chonnam Med J.
  • 2005 Apr;41(1):14-18.
The purpose of this study is to clarify the increasing effects of norepinephrine on the spontaneous activity of medial vestibular nuclear neurons of the rat. Sprague-Dawley rats aged 14 to...
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The Effect of Papaverine on the Calcium-dependent K+ Current in Rat Basilar Smooth Muscle Cells

Bai GY, Cho JW, Han DH, Yang TK, Gwak YG, Kim CJ

  • KMID: 1882180
  • J Korean Neurosurg Soc.
  • 2005 Nov;38(5):375-379.
OBJECTIVE: Papaverine has been used in treating vasospasm following subarachnoid hemorrhage(SAH). However, its action mechanism for cerebral vascular relaxation is not clear. Potassium channels are closely related to the contraction...
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The Effect of External Divalent Cations on Intestinal Pacemaking Activity

Kim BJ, Kim KW

  • KMID: 1600071
  • Korean J Physiol Pharmacol.
  • 2005 Aug;9(4):203-207.
Electrical rhythmicity in the gastrointestinal (GI) muscles is generated by pacemaker cells, known as interstitial cells of Cajal (ICC). In the present study, we investigated the effect of external divalent...
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Effects of Cyclic Nucleotide-Gated Channels in Vestibular Nuclear Neurons

Heo T, Jang S, Jeong HS, Park JS

This study was designed to investigate the effects an 8-Br-cGMP on the neuronal activity of rat vestibular nuclear cells. Sprague-Dawley rats aged 14 to 16 days were decapitated under ether...
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Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus

Shen Y, Han SK, Ryu PD

The hypothalamic paraventricular nucleus (PVN) contains two types of neurons projecting to either the rostral ventrolateral medulla (PVN(RVLM)) or the intermediolateral horn (IML) of the spinal cord (PVN(IML)). These two...
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The Role of Mitochondrial ATP-sensitive Potassium Channel on Intestinal Pacemaking Activity

Kim BJ, Kim KW

  • KMID: 1600073
  • Korean J Physiol Pharmacol.
  • 2005 Aug;9(4):209-213.
Interstitial cells of Cajal (ICCs) are the pacemaker cells that generate slow waves in the gastrointestinal (GI) tract. In the present study, we investigated the effect of mitochondrial ATP-sensitive potassium...
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Effect of propofol on ion channels in acutely dissociated dorsal raphe neuron of Sprague-Dawley rats

Lee BJ, Kwon MI, Shin MC, Kim YJ, Kim CJ, Kim SA, Kim EH, Chung JH

  • KMID: 2285240
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):189-197.
To investigate propofol's effects on ionic currents induced by gamma-aminobutyric acid (GABA) and glycine as well as on those produced by the nicotinic acetylcholine- and glutamate-responsive channels, rat dorsal raphe neurons were acutely...
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Protein Kinase C Activates ATP-sensitive Potassium Channels in Rabbit Ventricular Myocytes

Kim N, Youm JB, Joo H, Kim H, Kim E, Han J

  • KMID: 1600067
  • Korean J Physiol Pharmacol.
  • 2005 Aug;9(4):187-193.
Several signal transduction pathways have been implicated in ischemic preconditioning induced by the activation of ATP-sensitive K+ (KATP) channels. We examined whether protein kinase C (PKC) modulated the activity of...
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