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Inhibition of Pacemaker Activity of Interstitial Cells of Cajal by Hydrogen Peroxide via Activating ATP-sensitive K(+) Channels

Choi S, Parajuli S, Cheong HS, Paudyal DP, Yeum CH, Yoon PJ, Jun JY

  • KMID: 1512913
  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):15-20.
To investigate whether hydrogen peroxide (H2O2) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal (ICC) from murine small intestine by using a...
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(-)-Epigallocatechin Gallate Inhibits the Pacemaker Activity of Interstitial Cells of Cajal of Mouse Small Intestine

Kim KY, Choi SJ, Jang HJ, Zuo DC, Shahi PK, Parajuli S, Yeum CH, Yoon PJ, Choi S, Jun JY

The effects of (-)-epigallocatechin gallate (EGCG) on pacemaker activities of cultured interstitial cells of Cajal (ICC) from murine small intestine were investigated using whole-cell patch-clamp technique at 30degrees C and...
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Effects of ATP on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Small Intestine

Park IK, Kim JH, Park CG, Kim MY, Parajuli S, Hong CS, Choi S, Jun JY

Purinergic receptors play an important role in regulating gastrointestinal (GI) motility. Interstitial cells of Cajal (ICCs) are pacemaker cells that regulate GI smooth muscle activity. We studied the functional roles...
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Interplay of Hydrogen Sulfide and Nitric Oxide on the Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine

Yoon PJ, Parajuli S, Zuo DC, Shahi PK, Oh HJ, Shin HR, Lee MJ, Yeum CH, Choi S, Jun JY

We studied whether nitric oxide (NO) and hydrogen sulfide (H2S) have an interaction on the pacemaker activities of interstitial cells of Cajal (ICC) from the mouse small intestine. The actions...
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The Inhibitory Effects of Hydrogen Sulfide on Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine

Parajuli S, Choi S, Lee J, Kim YD, Park CG, Kim MY, Kim HI, Yeum CH, Jun JY

In this study, we studied whether hydrogen sulfide (H2S) has an effect on the pacemaker activity of interstitial cells of Cajal (ICC), in the small intestine of mice. The actions...
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