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MicroRNAs in Asthma and Respiratory Infections: Identifying Common Pathways

Taka S, Tzani-Tzanopoulou P, Wanstall H, Papadopoulos NG

MicroRNAs (miRs) are single-stranded RNAs of 18-25 nucleotides. These molecules regulate gene expression at the post-transcriptional level; several of these are differentially expressed in asthma as well as in viral...
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Omalizumab and unmet needs in severe asthma and allergic comorbidities in Japanese children

Nishima S, Kozawa M, Milligan K, Papadopoulos NG

Childhood asthma is one condition within a family of allergic diseases, which includes allergic rhinitis, atopic dermatitis, and food allergy, among others. Omalizumab is an anti-IgE antibody therapy that was...
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Innate Immune Response to Viral Infections in Primary Bronchial Epithelial Cells is Modified by the Atopic Status of Asthmatic Patients

Moskwa S, Piotrowski W, Marczak J, Pawełczyk M, Lewandowska-Polak A, Jarzębska M, Brauncajs , Głobińska A, Górski P, Papadopoulos NG, Edwards MR, Johnston S, Kowalski M

PURPOSE: In order to gain an insight into determinants of reported variability in immune responses to respiratory viruses in human bronchial epithelial cells (HBECs) from asthmatics, the responses of HBEC...
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Viral Agents Involved in Wheezing and Asthma in Children

  • KMID: 2234473
  • Korean J Asthma Allergy Clin Immunol.
  • 2008 Mar;28(1):1-9.
The role of respiratory viral infections in the development of childhood asthma remains under intense investigation. There is a plethora of viral agents (rhinoviruses [RV], enteroviruses, respiratory syncytial virus [RSV],...
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