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Tocolytic Effect of Morphine via Increased Metabolic Clearance of Oxytocin in the Baboon

Bai YH, Pak SC, Choi BC, Wilson L

Morphine is known to inhibit nocturnal uterine contractions in several animal models, and oxytocin is known to be a primary causative factor of uterine contractions. The purpose of the present...
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The effect of oxytocin antagonist on uterus in response to exogenous oxytocin

Park SH, Song CH, Pak SC, Flouret G, Wilson L

This study was performed to determine the action mode of oxytocin antagonist. In Study 1, the duration of in vivo action of oxytocin antagonist I (AI) was examined. After infusing...
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Oxytocin and Oxytocin Antagonist Metabolism in the Plasma of Pregnant Women

An TH, Pak SC, Ahn TG

  • KMID: 2270269
  • Korean J Obstet Gynecol.
  • 2002 Jun;45(6):921-925.
OBJECTIVE: Oxytocin antagonists maybe useful in inhibiting the uterine contractions of preterm labor. One such compound is TT-235. The purpose of this study was to compare the resistance of TT-235...
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Extrauterine Incubation of Fetal Goats Applying the Extracorporeal Membrane Oxygenation via Umbilical Artery and Vein

Pak SC, Song CH, So GY, Jang CH, Lee KH, Kim JY

The fetus is an unstable subject for an isolated physiological and biochemical study. To study the fetus in a controlled and stable environment, a trial was done using 12...
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Decursin induces apoptosis in glioblastoma cells, but not in glial cells via a mitochondria-related caspase pathway

Oh ST, Lee S, Hua C, Koo BS, Pak SC, Kim DI, Jeon S, Shin BA

Decursin is a major biological active component of Angelica gigas Nakai and is known to induce apoptosis of metastatic prostatic cancer cells. Recently, other reports have been commissioned to examine...
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Abdominopelvic Omentopexy to Prevent Postoperative Radiotherapy Complications in Rectal Cancer after Abdominoperineal Resection

Kim WJ, Lee SK, Pak SC, Oh ST, Kim SK, Kim IC

  • KMID: 2026073
  • J Korean Soc Coloproctol.
  • 2001 Dec;17(6):337-341.
PURPOSE: In rectal cancer, it is known that the postoperative radiotherapy is an effective way for reducing locoregional recurrence, especially if accompanied with concurrent chemotherapy. However, toxicity to small bowel...
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Change of blood gas and hemodynamics in the fetal goat undergoing ECMO through umbilical artery and vein

Song CH, So GY, Lee KH, Pak SC

  • KMID: 2076346
  • Korean J Obstet Gynecol.
  • 2001 Sep;44(9):1657-1663.
OBJECTIVES: The purpose of this study is to establish animal model of extracorporeal membrane oxygenation (ECMO) system that uses membreane type oxygenator and circulation circuit of umbilical artery and vein....
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Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification

Kobet RA, Pan X, Zhang B, Pak SC, Asch AS, Lee MH

The nematode Caenorhabditis elegans (C. elegans) offers a unique opportunity for biological and basic medical researches due to its genetic tractability and well-defined developmental lineage. It also provides an exceptional...
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MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation

Lee S, Oh ST, Jeong HJ, Pak SC, Park HJ, Kim J, Cho HS, Jeon S

Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this...
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