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Interation of Immune and Nervous Systmes

Chung HT, Lee MS, Pae HO, Pyun KH

  • KMID: 1540189
  • J Korean Soc Endocrinol.
  • 2000 Dec;15(6):684-695.
No Abstract Available.
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Heme Oxygenase-1: Its Therapeutic Roles in Inflammatory Diseases

Pae HO, Chung HT

Heme oxygenase (HO)-1 is an inducible enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of free heme into ferrous iron, carbon monoxide (CO), and biliverdin (BV),...
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Tumoricidal Effects of Taxol on Murine Bladder Tumor-2 ( MBT-2 ) via Nitric Oxide ( NO ) Production

Yoo JC, Pae HO, Chung HT, Oh SJ, Rim JS

  • KMID: 1192671
  • Korean J Immunol.
  • 1998 Jun;20(2):187-192.
No abstract available.
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Roles of Nitric Oxide and Tumor Necrosis Factor in Liver Inloammation Induced by C . parvum and LPS

Yoo JC, Pae HO, Chung HT, Jun CD, Kim YH, Kim SM, Park RK, Jin HS

  • KMID: 1192678
  • Korean J Immunol.
  • 1998 Jun;20(2):237-243.
No abstract available.
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Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection

Jeong GS, Oh GS, Pae HO, Jeong SO, Kim YC, Shin MK, Seo BY, Han SY, Lee HS, Jeong JG, Koh JS, Chung HT

  • KMID: 1110123
  • Exp Mol Med.
  • 2006 Aug;38(4):393-400.
Recently, it has been reported that curcumin, which is known as a potent antioxidant, acts as a non-stressful and non-cytotoxic inducer of the cytoprotective heme oxygenase (HO)-1. In this study,...
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Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells

Pae HO, Jeong GS, Jeong SO, Kim HS, Kim SA, Kim YC, Yoo SJ, Kim HD, Chung HT

  • KMID: 1047077
  • Exp Mol Med.
  • 2007 Jun;39(3):267-277.
In vascular smooth muscle cells (VSMCs), induction of the heme oxygenase-1 (HO-1) confers vascular protection against cellular proliferation mainly via its up-regulation of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) that is...
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Effects of Taxol on the Synthesis of Nitric Oxide in Murine Microglial Cells

Chung HT, Park RK, Jun CD, Kwak HJ, Yoo JC, Pae HO, Song JH

  • KMID: 2083004
  • Korean J Immunol.
  • 1997 Sep;19(3):383-390.
Taxol, an anticancer drug, blocks cell division by stabilizing microtubules. However, taxol has distinct cell-cycle-independent effects. For example, taxol and bacterial LPS induce strikingly similar responses in murine microglial cells....
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Dimethoxycurcumin, a Structural Analogue of Curcumin, Induces Apoptosis in Human Renal Carcinoma Caki Cells Through the Production of Reactive Oxygen Species, the Release of Cytochrome c, and the Activation of Caspase-3

Lee JW, Hong HM, Kwon DD, Pae HO, Jeong HJ

  • KMID: 2314590
  • Korean J Urol.
  • 2010 Dec;51(12):870-878.
PURPOSE: Curcumin (Cur) has been reported to induce apoptosis in human renal carcinoma Caki cells. Dimethoxycurcumin (DMC), one of several synthetic Cur analogues, has been reported to have increased metabolic...
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Effects of Oral Administration of Phellinus linteus on the Productions of the Th1- and Th2-type Cytokines in Mice

Oh GS, Pae HO, Choi BM, Kwon JW, Yun YH, Choi JH, Kwon TO, Park YC, Chung HT

BACKGROUND: The mushroom Phellinus linteus (PL) has been shown to have the anti-tumor and immunostimulatory effects. We hypothesized that the hot water extract of PL (WEPL) exerts its significant immunostimulatory...
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Triptolide Inhibits the Proliferation of Immortalized HT22 Hippocampal Cells Via Persistent Activation of Extracellular Signal-Regulated Kinase-1/2 by Down-Regulating Mitogen-Activated Protein Kinase Phosphatase-1 Expression

Koo HS, Kang SD, Lee JH, Kim NH, Chung HT, Pae HO

OBJECTIVE: Triptolide (TP) has been reported to suppress the expression of mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1), of which main function is to inactivate the extracellular signal-regulated kinase-1/2 (ERK-1/2), the...
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