- Paclitaxel inhibits the hyper-activation of spleen cells by lipopolysaccharide and induces cell death
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Kim HJ, Joo HG
- KMID: 2412600
- J Vet Sci.
- 2016 Dec;17(4):453-458.
- doi: 10.4142/jvs.2016.17.4.453
Paclitaxel was isolated from the bark of the Pacific yew, Taxus brevifolia, and used as an anticancer agent. Paclitaxel prevents cancer cell division by inhibiting spindle fiber function, inducing cell... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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- Comparative Effects of Ibandronate and Paclitaxel on Immunocompetent Bone Metastasis Model
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Chung YS, Kang HC, Lee T
- KMID: 2345895
- Yonsei Med J.
- 2015 Nov;56(6):1643-1650.
- doi: 10.3349/ymj.2015.56.6.1643
PURPOSE: Bone metastasis invariably increases morbidity and mortality. This study compares the effects of ibandronate and paclitaxel on bone structure and its mechanical properties and biochemical turnover in resorption markers... -
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- The role of Bcl-xL and nuclear factor-kappaB in the effect of taxol on the viability of dendritic cells
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Kim MH, Joo HG
- KMID: 1102965
- J Vet Sci.
- 2009 Jun;10(2):99-103.
- doi: 10.4142/jvs.2009.10.2.99
Taxol has been used effectively in cancer therapies. Our previous study demonstrated that taxol induced altered maturation and improved viability of dendritic cells (DCs). However, the effects of taxol on... -
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- Altered maturation of dendritic cells by taxol, an anticancer drug
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Joo HG
- KMID: 1089602
- J Vet Sci.
- 2003 Dec;4(3):229-234.
Taxol is a clinically useful anticancer drug against a variety of cancers. Although it has been known that taxol induces the apoptosis of cancer cells through cytochrome C release and... -
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