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Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Ozbek U

  • KMID: 1093619
  • Exp Mol Med.
  • 2003 Oct;35(5):454-459.
All-trans retinoic acid (ATRA) treatment of the acute promyelocytic leukemia (APL) have subsequently resulted in cell apoptosis, but the molecular mechanism of this effect remains elusive. In order to understand...
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Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemiat (15;17)patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Salcioglu , Sarper N, Ozbek U

  • KMID: 1097111
  • Exp Mol Med.
  • 2004 Jun;36(3):279-282.
Among several newly identified oncogenes, dek and af4 are attractive targets for researchers interested with leukemia. In this study quantitative Real-Time RT-PCR technique was used to define alterations in expression...
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