- Molecular genetics of gynecologic cancer
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Whang JD, Lee JH
- KMID: 1081028
- J Korean Med Sci.
- 1997 Oct;12(5):383-389.
- doi: 10.3346/jkms.1997.12.5.383
During the past decades, the expansion of molecular biology has had a pivotal role in understanding the basis of cancer development and progression. In addition, real advances have been... -
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- Expression and Mutational Analysis of c-kit in Ovarian Surface Epithelial Tumors
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Kim DJ, Lee MH, Park TI, Bae HI
- KMID: 2157787
- J Korean Med Sci.
- 2006 Feb;21(1):81-85.
- doi: 10.3346/jkms.2006.21.1.81
Coexpression of Kit ligand and c-kit has been reported in some gynecologic tumors. To determine whether imatinib mesylate is useful in ovarian epithelial tumors, we performed immunohistochemical and mutational analysis.... -
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- DNA Hypomethylation-Mediated Overexpression of Carbonic Anhydrase 9 Induces an Aggressive Phenotype in Ovarian Cancer Cells
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Sung HY, Ju W, Ahn JH
- KMID: 2070216
- Yonsei Med J.
- 2014 Nov;55(6):1656-1663.
- doi: 10.3349/ymj.2014.55.6.1656
PURPOSE: Both genetic and epigenetic alterations can lead to abnormal expression of metastasis-regulating genes in tumor cells. Recent studies suggest that aberrant epigenetic alterations, followed by differential gene expression, leads... -
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- AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration
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Park K, Chung YJ, So H, Kim K, Park J, Oh M, Jo M, Choi K, Lee EJ, Choi YL, Song SY, Bae DS, Kim BG, Lee JH
- KMID: 1097266
- Exp Mol Med.
- 2011 Feb;43(2):91-100.
- doi: 10.3858/emm.2011.43.2.011
Ovarian cancer is a leading cause of death in women. Early detection of ovarian cancer is essential to decrease mortality. However, the early diagnosis of ovarian cancer is difficult due... -
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- Overexpression of Mucin 13 due to Promoter Methylation Promotes Aggressive Behavior in Ovarian Cancer Cells
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Sung HY, Park AK, Ju W, Ahn JH
- KMID: 1799482
- Yonsei Med J.
- 2014 Sep;55(5):1206-1213.
- doi: 10.3349/ymj.2014.55.5.1206
PURPOSE: Recent discoveries suggest that aberrant DNA methylation provides cancer cells with advanced metastatic properties. However, the precise regulatory mechanisms controlling metastasis genes and their role in metastatic transformation are... -
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- Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference
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Jang JY, Yanaihara , Pujade-Lauraine E, Mikami Y, Oda K, Bookman M, Ledermann , Shimada M, Kiyokawa T, Kim BG, Matsumura , Kaku T, Kuroda T, Nagayoshi , Kawabata A, Iida Y, Kim JW, Quinn M, Okamoto A
- KMID: 2413437
- J Gynecol Oncol.
- 2017 Jul;28(4):e54.
- doi: 10.3802/jgo.2017.28.e54
There has been significant progress in the understanding of the pathology and molecular biology of rare ovarian cancers, which has helped both diagnosis and treatment. This paper provides an update... -
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- Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer
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Sung HY, Yang SD, Park AK, Ju W, Ahn JH
- KMID: 2374185
- Yonsei Med J.
- 2017 Jan;58(1):27-34.
- doi: 10.3349/ymj.2017.58.1.27
PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12... -
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