- Expression of Osteopontin in Osteoclast
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Chang JS, Park JH, Park YG, Kim JH
- KMID: 2199160
- J Korean Orthop Res Soc.
- 1999 Oct;2(2):132-138.
PURPOSE: This study was aimed to determine the relationship between osteopontin(OPN) and osteoclast, especially focused on whether ostecolast could produce osteopontin or not. MATERIALS AND METHODS: Osteoclasts were isolated from the... -
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- Effects of Osteopontin on Normal and Malignant Ovarian Epithelial Cell
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Park DC
- KMID: 2077527
- Korean J Obstet Gynecol.
- 2005 Dec;48(12):2919-2925.
OBJECTIVE: To evaluate the effects of both exogenous and endogenous osteopontin on normal and malignant ovarian epithelial cell growth, and on paclitaxel chemo-resistance. METHODS: The ovarian cancer cell line OV429,... -
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- Osteopontin and Developing Kidney
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Yim HE, Yoo KH
- KMID: 1578212
- J Korean Soc Pediatr Nephrol.
- 2006 Apr;10(1):1-7.
Osteopontin (OPN) is a glycosylated phosphoprotein which mediates cell adhesion and migration, and is produced by bone, macrophages, endothelial cells, and epithelial cells. The many regulatory functions of OPN include... -
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- Comparison between Osteopontin Expression and Renal Function in Spontaneous Renal Failure Model
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Lee DH, Kim SK, Hwang JH, Hyun BH, Kim YJ
- KMID: 2254519
- Korean J Nephrol.
- 2000 Sep;19(5):819-826.
Tubuolointerstitial inflammation and tubular injury account for most types of glomerulonephritis. The injury is characterized by an infiltration of mononuclear cells with atrophy and dilation of tubules and increased deposition... -
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- Osteopontin expression on benign and malignant ovarian tumors
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Lim OR, Won NH, Kim HS, Lee NW, Lee KW
- KMID: 2272437
- Korean J Obstet Gynecol.
- 2004 Nov;47(11):2149-2158.
OBJECTIVE: To understand the expression pattern of osteopontin on various histologic types of ovarian tumors. METHODS: We performed an immunohistochemical study on 90 paraffin embedded tissues including 80 ovarian epithelial tumors... -
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- Role of zinc for calcification inhibitor protein in vascular smooth muscle cell plaque formation
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Shin MY, Kwun IS
- KMID: 2158307
- J Nutr Health.
- 2016 Feb;49(1):59-62.
- doi: 10.4163/jnh.2016.49.1.59
PURPOSE: Zinc, a biomineral present within and outside cells, manages various cellular mechanisms. In this study, we examined whether zinc was involved in vascular smooth muscle cell (VSMC) calcification via... -
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- Expression of Osteopontin and Transforming Growth Factor-beta in Childhood Minimal Change Nephrotic Syndrome After Cyclosporine Treatment
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Lim BJ, Kim PK, Hong SW, Jeong HJ
- KMID: 2322066
- J Korean Soc Pediatr Nephrol.
- 2002 Oct;6(2):142-154.
PURPOSE: One of the most important adverse effects of long-term cyclosporine therapy is nephrotoxicity, the morphologic changes of which include interstitial fibrosis and arteriolar hyalinization. Recently, several authors have shown... -
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- The Immunohistochemical Patterns of Calcification-related Molecules in the Epidermis and Dermis of the Zebrafish (Danio rerio)
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Hong YJ, Choi YW, Myung KB, Choi HY
- KMID: 2171920
- Ann Dermatol.
- 2011 Aug;23(3):299-303.
- doi: 10.5021/ad.2011.23.3.299
BACKGROUND: The scales of bony fish represent a significant reservoir of calcium and calcification of the elasmoid scale is known to be associated with deposition of mineral crystals from the... -
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- Comparison of Serum Osteopontin Levels in Patients with Stable and Chronic Obstructive Pulmonary Disease and Exacerbation
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Ma JE, Lee SH, Kim YE, Lim SJ, Lee SJ, Jeong YY, Kim HC, Lee JD, Hwang YS, Cho YJ
- KMID: 2319553
- Tuberc Respir Dis.
- 2011 Sep;71(3):195-201.
BACKGROUND: Osteopontin (Opn) is recognized as an important adhesive bone matrix protein and a key cytokine involved in immune cell recruitment and tissue repair and remolding. However, serum levels of... -
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- Effects of irradiation on the mRNA expression of the osteocalcin and osteopontin in MC3T3-E1 osteoblastic cell line
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Cho SB, Ha SY, Lee SR, Koh KJ
- KMID: 1873588
- Korean J Oral Maxillofac Radiol.
- 2003 Sep;33(3):179-185.
PURPOSE: To investigate the effects of irradiation on the phenotypic expression of the MC3T3-E1 osteoblastic cell line, particularly on the expression of osteocalcin and osteopontin. MATERIALS AND METHODS: Cells were... -
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- Validation of Gene Expression Changes of Osteopontin and MMP-1 in Primary and Metastatic Colorectal Carcinomas
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Choi J, Kim S, Park JH, Kim NK, Kim H
- KMID: 1837525
- Korean J Pathol.
- 2010 Jun;44(3):225-233.
BACKGROUND: Metastasis is one of the most important characteristics of cancer in terms of its impact on patient survival. Unfortunately, identification of altered genes during tumor metastasis is limited. METHODS: Using... -
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- Expression of Osteopontin and Clusterin in Transitional Cell Carcinoma of the Bladder: Comparison to the Pathologic Stage
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Yoon JH, Lee JH, Yeom BW, Won NH, Yoon DK
- KMID: 2061107
- Korean J Urol.
- 2005 Apr;46(4):341-346.
PURPOSE: This study was performed to evaluate the expressions of osteopontin (OPN) and clusterin in a transitional cell carcinoma (TCC) of the urinary bladder, and then compare their expression rates... -
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- Effects of Individual or Combined Treatment with Enalapril and Lovastatin on the Osteopontin Gene Expression in 5/6 Nephrectomized Rats
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Kim SB, Park JS, Yang WS, Park SK, Lee SK, Lee JS
- KMID: 2307278
- Korean J Nephrol.
- 1999 Nov;18(6):877-886.
Osteopontin, a secreted, arginine-glycin-asparate (RGD)-containing phosphoprotein is up-regulated in renal cortex in many experimental models of tubu- lointerstitial fibrosis. Osteopontine gene seems to be induced predominantly in chronic and progressive... -
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- High Serum Osteopontin Levels Are Associated with Low Bone Mineral Density in Postmenopausal Women
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Cho EH, Cho KH, Lee HA, Kim SW
- KMID: 1777687
- J Korean Med Sci.
- 2013 Oct;28(10):1496-1499.
- doi: 10.3346/jkms.2013.28.10.1496
Osteopontin (OPN) is an acidic, noncollagenous matrix protein produced by the bone and kidneys. It is reportedly involved in bone resorption and formation. We examined the association between serum OPN... -
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- Immunohistochemical study of osteopontin in boar testis
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Kim S, Shin T
- KMID: 1089659
- J Vet Sci.
- 2007 Jun;8(2):107-110.
- doi: 10.4142/jvs.2007.8.2.107
The expression of osteopontin (OPN) in boar testis was studied. Western blot analysis detected 66- and 32-kDa OPN immunopositive bands in the testes of adult boars. In postnatal piglets, the... -
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- Significance of Osteopontin Expression in the Progression of Human Focal Segmental Glomerulosclerosis
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Yoon GS, Kim TS
- KMID: 2277553
- Korean J Pathol.
- 2010 Oct;44(5):462-468.
BACKGROUND: Osteopontin (OPN) is a cytokine related to cell-matrix adhesion and cell survival and is expressed in the distal convoluted tubules in normal adult kidneys. Only one in vitro study... -
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- Expression of Osteopontin, ZO-1 and E-cadherin in Adenoma and Adenocarcinoma of the Colon
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Jeong YK, Lee MJ, Lim SC, Kee KH, Jeon HJ, Suh CH
- KMID: 1855946
- Korean J Pathol.
- 2005 Aug;39(4):242-250.
Background : The expressions of osteopontin (OPN), zonula occludens-1 (ZO-1) and E-cadherin, known as cell adhesion-associated substances, were examined in adenoma and adenocarcinoma of the colon. The relationship of their... -
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- Podocyte Expression of Osteopontin and FSP-1/S100A4 in Human Crescentic Glomerulonephritis
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Yoon GS, Kim TS
- KMID: 1443728
- Korean J Pathol.
- 2011 Jun;45(3):237-246.
- doi: 10.4132/KoreanJPathol.2011.45.3.237
BACKGROUND: Osteopontin (OPN) is a cytokine associated with a cell-matrix via integrins. Fibroblast specific protein-1 (FSP-1), known as S100A4, has been implicated in cell migration by non-muscle myosin. We investigated... -
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- Osteopontin Genetic Polymorphism and Serum Levels in Patients with Systemic Lupus Erythematosus
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Kim HR, Song JS
- KMID: 2202127
- J Korean Rheum Assoc.
- 2009 Jun;16(2):115-122.
- doi: 10.4078/jkra.2009.16.2.115
OBJECTIVE: A recent study suggested that a single nucleotide polymorphism (SNP) at position nt 9250 (C to T) in exon 7 of the osteopontin (OPN) gene is strongly associated with... -
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- Beta-catenin, Frizzled-2, BMP-4, Osteopontin, Osteocalcin, and Osteonectin Expression in Calcifying Basal Cell Carcinoma
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Do MO, Kim SY, Choi YW, Myung KB, Choi HY
- KMID: 2087380
- Korean J Dermatol.
- 2007 Jul;45(7):666-672.
BACKGROUND: Although basal cell carcinoma (BCC) is the most common human skin tumor, with calcification reportedly taking place in about 20% of all BCC cases, the pathogenesis of calcification in... -
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