- Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells
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Gong X, Wang M, Wu Z, Tashiro SI, Onodera S, Ikejima T
- KMID: 1103322
- Exp Mol Med.
- 2004 Dec;36(6):551-556.
Pseudolaric acid B was isolated from Pseudolarix kaempferi Gordon (Pinaceae) and was evaluated for the anti-cancer effect in HeLa cells. We observed that pseudolaric acid B inhibited cell proliferation and... -
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- D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells
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Kwon KB, Park EK, Ryu DG, Park BH
- KMID: 1093595
- Exp Mol Med.
- 2002 Mar;34(1):32-37.
Daunorubicin, an anti-cancer drug, is known to induce apoptosis in HL-60 cells in a dose-dependent manner through the activation of caspase-3 (CPP32). Caspase-3 selective inhibitor, Ac-DEVD-CHO, prevented both the activation... -
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- Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A2 and 12-PGJ2.
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Ahn SG, Kim HS, Jeong SW, Kim BE, Rhim HS, Shim JY, Kim JW, Lee JH, Kim IK
- KMID: 1380233
- Exp Mol Med.
- 2002 Jul;34(3):243-249.
We reported earlier that expression of Sox-4 was found to be elevated during prostaglandin (PG) A2 and delta(12)-PGJ(12) induced apoptosis in human hepatocarcinoma Hep3B cells. In this study, the role... -
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- Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL
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Woo KM, Kim HM, Ko JS
- KMID: 755205
- Exp Mol Med.
- 2002 Nov;34(5):340-346.
Macrophage colony-stimulating factor (M-CSF) is known as one of the factors essential for osteoclast development. In the present study, we examined effects of M-CSF on the apoptotic pathway of osteoclast... -
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- The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis
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Kim SD, Kwon S, Lee SK, Kook M, Lee HY, Song KD, Lee HK, Baek SH, Park CB, Bae YS
- KMID: 2154259
- Exp Mol Med.
- 2013 Sep;45(9):e40.
In this study, we examined the therapeutic effects of an immune-stimulating peptide, WKYMVm, in ulcerative colitis. The administration of WKYMVm to dextran sodium sulfate (DSS)-treated mice reversed decreases in body... -
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- Effect of angiopeptin and aspirin on accelerated graft atherosclerosis in transplanted mouse heart
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Lee JR, Yang JH, Kim EK, Seo JW
- KMID: 646035
- J Korean Med Sci.
- 1999 Dec;14(6):607-612.
- doi: 10.3346/jkms.1999.14.6.607
In this study of the inhibitory effects of angiopeptin and aspirin on the development of accelerated graft atherosclerosis (AGAS), 22 B10.BR mice received intra-abdominal heterotopic heart transplants from B10.A mice,... -
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- Determination of angiotensin I-converting enzyme activity in equine blood: lack of agreement between methods of analysis
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Costa MF, Carmona AK, Alves MF, Ryan TM, Davies HM, Anderson G, Slocombe R
- KMID: 1067333
- J Vet Sci.
- 2011 Mar;12(1):21-25.
- doi: 10.4142/jvs.2011.12.1.21
Angiotensin-I converting enzyme (ACE) is a key regulator of blood pressure, electrolytes and fluid homeostasis through conversion of angiotensin I into angiotensin II. Recently, a genetic polymorphism of the ACE... -
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