- High Dose Ofloxacin-induced Bimodal Hallucinations in a 4 Years Old Child
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Bhattacharya A, Sharan R, Praharaj S
- KMID: 2396315
- Clin Psychopharmacol Neurosci.
- 2017 Nov;15(4):416-417.
- doi: 10.9758/cpn.2017.15.4.416
Ofloxacin is a commonly used quinolone antibiotic both in adults as well as children. It is generally safe and well tolerated. Rarely, neurological and psychiatric adverse reactions are reported to... -
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- Activity of Moxifloxacin Against Ofloxacin-Resistant Mycobacterium Tuberculosis: A Study of Cross-Resistance Between Ofloxacin and Moxifloxacin
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Kim BJ, Kang YS, Park SK
- KMID: 2318507
- Tuberc Respir Dis.
- 2004 Nov;57(5):405-410.
BACKGROUND: Moxifloxacin is an 8-methoxyquinolone compound which has been shown to have the best activity of the quinolones against M. tuberculosis but there is no literature showing the rate of... -
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- In vitro activities of meropenem, imipenem and ofloxacin against aerobic gram-negative bacilli and gram-positive cocci
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Chong Y, Lee K, Lee SY
- KMID: 1699630
- Korean J Infect Dis.
- 1991 May;23(2):95-105.
No abstract available. -
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- Treatment of Uncomplicated Male Gonococcal Urethritis with Ofloxacin
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Nam TS, Kim YT, Kim JH
- KMID: 1891657
- Korean J Dermatol.
- 1988 Dec;26(6):867-873.
Ofloxacin, one of the new quinolone derivatives, is found to be highly effective against both PPNG and non-PPNG urethritis. The objective of this trial was to establish the efficacy of... -
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- Anaphylactoid reaction to ofloxacin with cross-reactivity to other fluoroquinolones
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Kim CW, Kim DY, Ryu ST, Kang SY, Jang CS
- KMID: 2285828
- J Asthma Allergy Clin Immunol.
- 2004 Mar;24(1):146-151.
Fluoroquinolones are antimicrobial agents that have a broad range of activity against both gram-negative and gram-positive organisms. Anaphylactoid reactions have been sporadically reported with fluoroquinolones. There have been a few... -
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- Ocular Penetration of Topical Ofloxacin in Rabbit Eye with Amniotic Membrane Transplantation
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Kim HS, Moon JI, Sah WJ, Kim YJ, Kim JC, Hahn TW
- KMID: 2109215
- J Korean Ophthalmol Soc.
- 2001 Sep;42(9):1315-1324.
PURPOSE: We evaluated ocular penetration and drug level in tear after topical ofloxacin instillation in rabbit eye with amniotic membrane transplantation(AMT). METHODS: In the first set of experiment, 24 rabbits(24... -
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- Corneal Ulcer and Chronic Conjunctivitis Due to Ofloxacin-resistant MRSA
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Suh Y, Shin EM, Hahn TW
- KMID: 2125379
- J Korean Ophthalmol Soc.
- 2002 Feb;43(2):419-423.
PURPOSE: Considering popular use of fluoroquinolone eyedrops in Korea, it is important to know emerging resistant strain in treating infectious eye disease. We report methicillin resistant Staphylococcus aureus after frequent... -
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- A Case of Ofloxacin-induced Torsades de Pointes and Abnormal ECG Change Mimicking Acute Myocardial Infarction
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Kim JH, Nam GB, Lim JM, Huh JW, Kim SY, Rhee KS, Choi KJ, Kim YH
- KMID: 2227260
- Korean Circ J.
- 2002 Sep;32(9):815-819.
- doi: 10.4070/kcj.2002.32.9.815
While some fluoroquinolone antibiotics can cause QT prolongation and Torsades de Pointes (TdP), serious proarrhythmic effects from ofloxacin have not been reported. Here, we report a case of ofloxacin-induced Torsades... -
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- Immunologic Evaluation of Ofloxacin Hypersensitivity
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Nam YH, Kim JE, Kim SH, Jin HJ, Hwang EK, Shin YS, Ye YM, Park HS
- KMID: 2167029
- Allergy Asthma Immunol Res.
- 2012 Nov;4(6):367-369.
- doi: 10.4168/aair.2012.4.6.367
Quinolone hypersensitivity, most of which is immediate type, is rare but has increased in recent years. The pathogenic mechanisms underlying immediate reactions are not defined clearly. This study was aimed... -
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- The Effect of Antibiotics in the Irrigation Solution on Corneal Endothelial Function
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Kim JH, Kim KS, Lee JH
- KMID: 2124697
- J Korean Ophthalmol Soc.
- 2000 Jun;41(6):1272-1278.
The practice of adding antibiotics to anterior chamber-irrigating solutions as a prophylaxis for endophthalmitis has been used recently.To evaluate corneal endothelial toxicity of different concentrations of antibiotics in irrigating solutions,... -
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- The Distribution and Concentration of Ofloxacin Contained in Sustained Releasing Microsphere after Intraprostatic Injection
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Bahk JY, Hyun JS, Lee GI, Park HC, Baik SH, Park J, Lee JH, Kim MO, Lee JY, Kim J, Cho YH
- KMID: 2290418
- Korean J Urol.
- 1999 Dec;40(12):1577-1582.
PURPOSE: Sporadic excellent treatment results of intra-prostatic antibiotic injections against resistant chronic prostatitis were reported without sufficient background. So, for the scientific base of this effective treatment modality, we studied... -
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- Pharmacokinetics of ofloxacin in Patients with Multidrug-Resistant Tuberculosis
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Park SK, Yoon YR, Lee WC, Jun HM, Shon JH, Kim KA, Park JY, Shin JG
- KMID: 2050261
- Tuberc Respir Dis.
- 2002 Feb;52(2):128-136.
- doi: 10.4046/trd.2002.52.2.128
BACKGROUND: There are few studies that have reported on the pharmacokinetic(PK) disposition of fluoroquinolones in patients with multi-drug resistant tuberculosis(MDR-Tb), even though fluoroquinolones are frequentl y co-prescribed to those patients.... -
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- Periocular Allergic Contact Dermatitis Associated with the Use of Ofloxacin Ophthalmic Ointment: A Case Report
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Jo JW, Jeong HB, Shin YB, Kang KR, Kim CY
- KMID: 2437056
- Korean J Dermatol.
- 2018 Dec;56(10):624-627.
Allergic contact dermatitis is an inflammatory condition associated with periorbital erythema, edema, and pruritus. The periorbital skin is relatively thin compared with the skin over other facial areas; therefore, it... -
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- The Antibacterial Activity of Domestic Toipcal Antibiotics II: In Vitro
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Yang JG, Lee JH
- KMID: 2123731
- J Korean Ophthalmol Soc.
- 1997 Feb;38(2):207-213.
To Assess the efficacy of the new domestic topical antibiotic eyedrops, we evaluated in vitro the antimicrobial activity of Ciprus (ciprofloxacin), Ofloxacin (ofloxacin), Tobramycin (tobramycin), and Ecolicin (erythromycin and colistin)... -
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- In-Vitro Activity of Tosufloxacin Compared with Levofloxacin and Ofloxacin against Uropathogens, Isolated from Acute Uncomplicated Cystitis in Female Outpatients
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Lee SJ, Lee KS, Jeong SJ, Lee SE, Cho YH
- KMID: 1528884
- Infect Chemother.
- 2007 Aug;39(4):202-207.
BACKGROUND: Tosufloxacin is one of the fluoroquinolones with higher antibacterial activity against many organisms than other fluoroquinolones developed previously. However, the antimicrobial susceptibilities of tosufloxacin against uropathogens are not well... -
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- The Changes in the Corneal Epithelial Barrier by Benzalkonium Chloride and Commonly used Eyedrops
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Lee JH, Kim KS
- KMID: 2205136
- J Korean Ophthalmol Soc.
- 1995 Oct;36(10):1655-1661.
To evaluate the corneal epithelial barrier after exposure to Benzalkonium chloride(BAC) or commonly used eyedrops, we measured corneal uptake of 5, 6-carboxyfluorescein(CF) applied to the corneal epithelium of the albino... -
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- Concentrations of Ofloxacin, Levofloxacin and Ciprofloxacin in Human Aqueous Humor after Topical Administration
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Han YS, Nam DH, Shyn KH, Park JY, Kim KA, Kim SW, Song JS
- KMID: 2126258
- J Korean Ophthalmol Soc.
- 2005 Apr;46(4):605-609.
PURPOSE: To evaluate the concentrations of commercially available ofloxacin 0.3%, levofloxacin 0.5%, and ciprofloxacin 0.3% topical ophthalmic solutions in human aqueous humor. METHODS: Patients scheduled to undergo phacoemulsification and posterior... -
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- The Clinical Efficacy of Levofloxacin(CRAVIT(R)) in the Treatment of Cutaneous Infection
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Kang HJ, Kim HJ, Seo SL, Kim YS, Lee MA, Hahm JH
- KMID: 2170904
- Ewha Med J.
- 1996 Sep;19(3):359-364.
- doi: 10.12771/emj.1996.19.3.359
BACKGROUND: Levofloxacin, an oral fluroquinolone antibacterial agent, is the optical S-(-) isomer of ofloxacin. In vitro it is generally twice as potent as ofloxacin and active against most aerobic gram... -
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- Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach
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Sood D, Kumar N, Singh A, Sakharkar , Tomar V, Chandra R
- KMID: 2422811
- Genomics Inform.
- 2018 Sep;16(3):44-51.
- doi: 10.5808/GI.2018.16.3.44
Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary... -
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- Comparison of the E-test with agar dilution susceptibility test by using bacteroides fragilis
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Kim HS, Kim SK, Cha HS
- KMID: 2154934
- Yeungnam Univ J Med.
- 1993 Jun;10(1):135-143.
- doi: 10.12701/yujm.1993.10.1.135
The susceptibilities of 45 clinical isolates of bacteroidis fragilis to cefaclor, ciproflxacin and imipenem were determined by new method, E-test (AB Bidisk, Solna, Sweden) and were compared with those from... -
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