- Role of Loss of O(6)-Methylguanine DNA Methyltransferase (MGMT) Expression in Non-Small Cell Lung Carcinomas (NSCLCs): with Reference to the Relationship with p53 Overexpression
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Myong NH
- KMID: 2165964
- Cancer Res Treat.
- 2010 Jun;42(2):95-100.
PURPOSE: Functional inactivation of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene has been demonstrated as loss of MGMT protein and suggested that it plays an important role in primary human neoplasia, including... -
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- Appraisal of re-irradiation for the recurrent glioblastoma in the era of MGMT promotor methylation
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Kim IH
- KMID: 2447546
- Radiat Oncol J.
- 2019 Mar;37(1):1-12.
- doi: 10.3857/roj.2019.00171
Despite recent innovation in treatment techniques and subsequently improved outcomes, the majority of glioblastoma (GBL) have relapses, especially in locoregional areas. Local re-irradiation (re-RT) has been established as a feasible... -
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- DNA Hypermethylation of Tumor-Related Genes in Gastric Carcinoma
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Hong SH, Kim HG, Chung WB, Kim EY, Lee JY, Yoon SM, Kwon JG, Sohn YK, Kwak EK, Kim JW
- KMID: 1095197
- J Korean Med Sci.
- 2005 Apr;20(2):236-241.
- doi: 10.3346/jkms.2005.20.2.236
The hypermethylation of the CpG islands is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed the methylation status of genes for cell repair... -
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- Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines
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Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW
- KMID: 648358
- J Korean Med Sci.
- 2001 Dec;16(6):756-761.
- doi: 10.3346/jkms.2001.16.6.756
Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of... -
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