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Nucleoside Diphosphate Kinase from Microorganisms

Choi CH

Nucleoside diphosphate kinase (Ndk) is ubiquitous and highly conserved multifunctional key enzyme in nucleotide metabolism. It generates nucleoside triphosphates (NTPs) by transfer of gamma-phosphates from nucleoside triphosphates such as ATP...
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Protective Efficacy of Recombinant Proteins Adenylate Kinase, Nucleoside Diphosphate Kinase, and Heat-Shock Protein 70 against Mycobacterium tuberculosis Infection in Mice

Lee SH, Lee EG, Kim SY, Cho SN, Park YK, Bai GH

  • KMID: 2318536
  • Tuberc Respir Dis.
  • 2005 Feb;58(2):142-151.
BACKGROUND: Priming and boosting vaccination strategy has been widely explored for new vaccine development against tuberculosis. As an effort to identify other vaccine candidates, this study was initiated to evaluate...
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Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study

Ro YS, Jeong SJ

Expression of nucleoside diphosphate(NDP) kinase, which is homologous to the nm23 gene product in a variety of species, has been found to be inversely associated with metastatic potential. However, the...
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Modulation of ATP-induced activation of the muscarinic K+ channel activity by protein kinase C

Kim YM, Park HK, Han JH, Park CO, Hong SG

  • KMID: 2071833
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):743-753.
The atrial acetylcholine-activated K+ (KACh) channel is gated by the pertussis toxin-sensitive inhibitory G (GK) protein. Earlier studies revealed that ATP alone can activate the KACh channel via transphosphorylation mediated by nucleoside-diphosphate kinase...
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nm23-H1 Protein Expression and Gene Mutation in 150 Patients with Non-Hodgkin's Lymphomas

Lee JH, Cho SJ, Zhang X, Zheng Z, Lee ES, Kim A, Kim YS, Chae YS, Kim I

The metastasis-suppressing role of the nm23 gene in the metastatic spread of malignant tumor is still debated. We examined the nm23-H1 protein expression and gene mutation in non-Hodgkin's lymphomas to...
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Cancer Metastasis and Metastasis Suppressors

Song IH

  • KMID: 1111502
  • Korean J Gastroenterol.
  • 2004 Jan;43(1):1-7.
Cancer metastasis, a complex and sequential network of cellular events involved in the migration and establishment of malignant cells from original site to distant foci, is an important and significant...
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Expression of p53 and NDP-K/nm23 in gastric carcinomas: association with metastasis and clinicopathologic parameters

Kim KM, Lee A, Chae HS, Shim SI

To evaluate the role of p53 and NDP-K/nm23(nm23) protein as a prognostic factor and their relation to metastasis of cancer, we studied metastatic and nonmetastatic gastric carcinoma specimens by immunohistochemical...
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Analysis of nm23 expression as a prognostic parameter in renal cell carcinoma

Park DS, Cho NH, Lee YT, Park C, Lee JM

To identify the clinicopathological events including nm23 expression that underlies progression in renal cell carcinoma, a retrospective analysis of patients with renal cell carcinoma was performed. Ninety-eight cases of radical...
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