- Detection of leptoapiral DNA by nucleic acid hybridization with 32P-labeld probe
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Kim SY, Chang WH, Kim IS
- KMID: 1687910
- J Korean Soc Microbiol.
- 1991 Aug;26(4):329-335.
No abstract available. -
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- Development of Multiplex PCR Detection of Blood-borne Viruses by Nucleic Acid Hybridization
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Yi HA, Kim HR, Lee HM, Park MS, Hong SH, Yoo SH, Lee CH
- KMID: 2055005
- J Bacteriol Virol.
- 2004 Jun;34(2):129-136.
Polymerase chain reaction (PCR) has been used as a substitute for conventional serological methods in order to provide blood or blood products free from contaminating viruses and recently attempts have... -
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- Assessment of the Specificity of A Hybridization of Surfactant Protein A by Addition of Non-specific Rat Spleen RNA
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Kim BC, Kim MO, Kim TH, Sohn JW, Yoon HJ, Shin DH, Park SS
- KMID: 2318478
- Tuberc Respir Dis.
- 2004 Apr;56(4):393-404.
BACKGROUND: Nucleic acid hybridization has become an essential technique in the development of our understanding of gene structure and function. The quantitative analysis of hybridization has been used in the... -
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- A Study of Detection of Human Papilloma Virus in the Patients with the Uterine Cervical Cancer by the Hybrid Capture System Method
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Cho SM, Han SJ
- KMID: 1928745
- Korean J Gynecol Oncol Colposc.
- 1997 Sep;8(3):266-270.
Tbe presence of certain HPV types in the female genital tract was associated with a number of diseases, including condyloma, cervical, vaginal and vulvar intraepithelial neoplasia and carcinoma. It is... -
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- The Chromosomal Aberrations in the Head and Neck Squamous Cell Carcinoma Cell Lines:PCI-1, PCI-13 and PCI-50
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Moon YE, Choi YS, Yeon JY, Chi AR, Lee DW
- KMID: 2277096
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Sep;52(9):741-750.
- doi: 10.3342/kjorl-hns.2009.52.9.741
BACKGROUND AND OBJECTIVES: The knowledge about chromosomal aberrations manifestated in cancer has been spotlighted recently. The genetic analyses based on the knowledge about chromosomal aberrations are important for the development... -
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- Analysis of the factors affecting the accuracy of detection for single base alterations by oligonucleotide microarray
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Liu S, Li Y, Fu X, Qiu M, Jiang B, Wu H, Li R, Mao Y, Xie Y
- KMID: 755744
- Exp Mol Med.
- 2005 Apr;37(2):71-77.
The oligonucleotide microarray, a high-throughput polymorphism detection technology, holds great promise for the characterization of complex genetic variance. To achieve greater sensitivity and specificity for it to be an effective... -
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- Recent Advances in Cancer Diagnosis: On an Overview of Diagnostic Cytopathologic Modalities and Ancillary Techniques
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Kim K, Keun E
- KMID: 2226486
- Korean J Cytopathol.
- 1996 Jun;7(1):1-11.
Form the concepts of cellular pathology and of exfoliative cytology, as elucidated by Virchow and Papanicolaou respectively in the late 19th and early 20th century, have evolved the primary methods... -
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- 1p36 deletion syndrome confirmed by fluorescence in situ hybridization and array-comparative genomic hybridization analysis
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Kang DS, Shin E, Yu J
- KMID: 2362246
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S14-S18.
- doi: 10.3345/kjp.2016.59.11.S14
Pediatric epilepsy can be caused by various conditions, including specific syndromes. 1p36 deletion syndrome is reported in 1 in 5,000–10,000 newborns, and its characteristic clinical features include developmental delay, mental... -
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- Genomic Imbalances in Ependymoma by Degenerate Oligonucleotide Primed PCR-Comparative Genomic Hybridization
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Park SH, Kim GJ, Kim MK, Kim H, Suh YL, Park SH
- KMID: 2275493
- Korean J Pathol.
- 2004 Jun;38(3):133-137.
BACKGROUND: The most consistent chromosomal abnormality in ependymomas, is loss of 22q (17-75%) and gain of 1q (0-50%). However, significance of this abnormality is uncertain. METHODS: Genomic imbalances in 27 Korean... -
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- Oncogene expressions detected by in situ hybridization of squamous metaplasia, dysplasia and primary lung cancer in human
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Lee JD, Lee DH, Park SS, Shin DH, Chung HC, Lee JH
- KMID: 1421458
- J Korean Med Sci.
- 1989 Sep;4(3):121-127.
- doi: 10.3346/jkms.1989.4.3.121
In order to elucidate the dynamic changes of oncogene expression in the sequential cascade of squamous metaplasia, dysplasia, and squamous cell carcinoma of the bronchial epithelium, hybridization in situ was... -
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- Comparative study of serum soluble interleukin-2 receptor and hepatitis C virus RNA in patients with chronic hepatitis C virus infection
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Yang YS, Ki CS, Kim JW
- KMID: 1892655
- Korean J Clin Pathol.
- 1997 Oct;17(5):781-790.
BACKGROUND: T cell mediated immune destruction is an important mechanism of liver injury in patients with chronic hepatitis C. Serum levels of soluble interleukin-2 receptor(sIL-2R) seem to serve as a... -
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- Reverse-SSO hybridization provides an accurate and simple HLA-DR typing: a comparative study with HLA-DR serologic typing
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Lee KW, Cho HC
- KMID: 644830
- J Korean Med Sci.
- 1994 Oct;9(5):414-426.
- doi: 10.3346/jkms.1994.9.5.414
The HLA-DR molecule is a polymorphic membrane glycoprotein and one of the key molecules causing allograft rejection and graft-versus-host disease in organ transplantation. Serologic typing using DR specific alloantisera has... -
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- Evaluation of Peptide Nucleic Acid Probe-based Real-time PCR for Detection of Mycobacterium tuberculosis Complex and Nontuberculous Mycobacteria in Respiratory Specimens
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Choi YJ, Kim HJ, Shin HB, Nam HS, Lee SH, Park JS, Park KS, Baek KA
- KMID: 1380084
- Ann Lab Med.
- 2012 Jul;32(4):257-263.
- doi: 10.3343/alm.2012.32.4.257
BACKGROUND: A peptide nucleic acid (PNA) probe-based real-time PCR (PNAqPCR(TM) TB/NTM detection kit; PANAGENE, Korea) assay has been recently developed for the simultaneous detection of Mycobacterium tuberculosis complex (MTBC) and... -
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- Comparison of Molecular Biologic Methods for Detecting HBV-DNA in the Sera which Showed Both Hepatitis B Surface Antigen and Antibody Positivity
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Kim MJ, Kim HS, Kwon OH, Hahn KH
- KMID: 2146213
- Korean J Clin Pathol.
- 1997 Dec;17(6):1124-1136.
BACKGROUND: Serologic markers are used to screen and diagnose the hepatitis B virus infection. In endemic area of hepatitis B, the coexistence of HBsAg and anti-HBs was frequently observed. This... -
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- Clinical Significance of an HPV DNA Chip Test with Emphasis on HPV-16 and/or HPV-18 Detection in Korean Gynecological Patients
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Yeo MK, Lee A, Hur SY, Park JS
- KMID: 2345552
- J Pathol Transl Med.
- 2016 Jul;50(4):294-299.
- doi: 10.4132/jptm.2016.05.09
BACKGROUND: Human papillomavirus (HPV) is a major risk factor for cervical cancer. METHODS: We evaluated the clinical significance of the HPV DNA chip genotyping assay (MyHPV chip, Mygene Co.) compared with... -
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- A case of isodicentric chromosome 15 presented with epilepsy and developmental delay
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Kim JS, Park J, Min BJ, Oh SK, Choi JS, Woo MJ, Chae JH, Kim KJ, Hwang YS, Lim BC
- KMID: 2409223
- Korean J Pediatr.
- 2012 Dec;55(12):487-490.
We report a case of isodicentric chromosome 15 (idic(15) chromosome), the presence of which resulted in uncontrolled seizures, including epileptic spasms, tonic seizures, and global developmental delay. A 10-month-old female... -
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- Point mutation at codon 12 of the c-Ha-ras gene in human gastric cancers.
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Koh EH, Chung HC, Lee KB, Han EK, Oh SH, Min JS, Choi EM, Youn JK, Kim BS
- KMID: 1421899
- J Korean Med Sci.
- 1992 Jun;7(2):110-115.
- doi: 10.3346/jkms.1992.7.2.110
The molecular mechanisms of the carcinogenic process of gastric cancer have not been fully understood yet. In order to know whether c-Ha-ras gene is being involved in the process... -
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- Analysis of Genomic Imbalances in Korean Gastric Carcinoma Using Comparative Genomic Hybridization
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Park SY, Hwang HJ, Lee CJ, Park SH
- KMID: 2092850
- Korean J Anat.
- 2004 Dec;37(6):539-547.
Chromosomal abnormalities, which are valuable markers for diagnosis and prognosis of cancer, provide useful clues in characterizing cancer at molecular level. Gastric cancer is the major cause of cancer deaths... -
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- Amplification of the UQCRFS1 Gene in Gastric Cancers
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Jun KH, Kim SY, Yoon JH, Song JH, Park WS
- KMID: 2372422
- J Gastric Cancer.
- 2012 Jun;12(2):73-80.
PURPOSE: The specific aim of this study is to unravel a DNA copy number alterations, and to search for novel genes that are associated with the development of Korean gastric... -
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- Chromosome 11q13 deletion syndrome
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Kim YS, Kim GH, Byeon JH, Eun SH, Eun BL
- KMID: 2362245
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S10-S13.
- doi: 10.3345/kjp.2016.59.11.S10
Chromosome 11q13 deletion syndrome has been previously reported as either otodental syndrome or oculo-oto-dental syndrome. The otodental syndrome is characterized by dental abnormalities and high-frequency sensorineural hearing loss, and by... -
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