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Comparison of bromodeoxyuridine and proliferating cell nuclear antigen labeling in gastric carcinoma

Kang SM, Kim WH, Kim CW, Kim YI

The proliferative activity of human gastric carcinoma was measured by means of in vitro incorporation of the thymidine analogue, 5-bromo-2'-deoxyuridine (BrdU), into the newly-synthesized DNA of fresh tumors and immunohistochemical...
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Prognostic significance of proliferating cell nuclear antigen-positive growth fraction in gastric adenomas

Kim WH, Choi GY, Kim YI

The proliferative activity of gastric adenomas from 18 patients (42 endoscopic procedures) was compared with follow-up results. These cases were gastric adenomas proven by follow-up with repeated endoscopic procedures...
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Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation

Lee SJ, Lee JK, Maeng YS, Kim YM, Kwon YG

Protein phosphatase-1 (PP1) nuclear targeting subunit (PNUTS), also called PP1R10, p99, or CAT 53 was originally isolated as a mammalian nuclear PP1-binding protein. In this study, we performed yeast two-hybrid...
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Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival

Chaurasia , Park SH, Seo JW, Park CK

Glioblastoma (GBM) can be classified into molecular subgroups, on the basis of biomarker expression. Here, we classified our cohort of 163 adult GBMs into molecular subgroups according to the expression...
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The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat

Lee K, Lee KM, Kim TJ, Han JS, Kim MK, Hong YS, Park GH, Lee KW

  • KMID: 1103324
  • Exp Mol Med.
  • 2004 Dec;36(6):563-571.
Methylation events play a critical role in various cellular processes including regulation of gene transcription and proliferation. We observed that methyltransferase activity underwent time-dependent changes in the cytosol of the...
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Nuclear protein binding patterns in the 5'-upstream regulatory elements of HLA class I genes

Park JH, Kim JD, Kim SJ

The expression of MHC class I genes has been thought to be regulated by two major cis-acting regulatory elements. The first region, enhancer A (Enh A) spanning from positions -210...
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Ovarian Clear Cell Carcinoma Sub-Typing by ARID1A Expression

Choi JY, Han HH, Kim YT, Lee JH, Kim BG, Kang S, Cho NH

PURPOSE: Loss of AT-rich DNA-interacting domain 1A (ARID1A) has been identified as a driving mutation of ovarian clear cell carcinoma (O-CCC), a triple-negative ovarian cancer that is intermediary between serous...
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Immunoexpression of HBME-1, High Molecular Weight Cytokeratin, Cytokeratin 19, Thyroid Transcription Factor-1, and E-cadherin in Thyroid Carcinomas

Choi YL, Kim MK, Suh JW, Han J, Kim JH, Yang JH, Nam SJ

To examine the immunohistochemical alterations associated with the histological dedifferentiation of thyroid carcinomas, we performed staining for HBME-1, high molecular weight cytokeratin (HCK), CK 19, thyroid transcription factor-1 (TTF-1) and...
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AROS Is a Significant Biomarker for Tumor Aggressiveness in Non-cirrhotic Hepatocellular Carcinoma

Kwon JH, Ahn KS, Moon YH, Park JY, Wang HJ, Choi KY, Kim G, Joh JW, Lee KG, Kang KJ

Despite a low risk of liver failure and preserved liver function, non-cirrhotic hepatocellular carcinoma (HCC) has a poor prognosis. In the current study, we evaluated an active regulator of SIRT1...
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