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Application of Artificial Intelligence in Nuclear Neuroimaging

 Park KS

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Are the Nuclear Neuro-Imaging Biomarkers Reliable?

Henry Bom HS,  Kim J,  Yun M, Kang DY

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Imaging Procedure and Clinical Studies of ­[18 F]FP‑CIT PET

Sung C, Oh S, Kim J

N-3-[18F]fluoropropyl-2β-carbomethoxy-3β-4-iodophenyl nortropane ­([18F]FP-CIT) is a radiopharmaceutical for dopamine transporter (DAT) imaging using positron emission tomography (PET) to detect dopaminergic neuronal degeneration in patients with parkinsonian syndrome. ­[18F]FP-CIT was granted approval...
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Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma

Kim D, Lee S,  Hwang H, Kim S, Yun M

Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted...
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The development status of PET radiotracers for evaluating neuroinflammation

Lee N,  Choi J, Ryu Y

Neuroinflammation is associated with the pathophysiologies of neurodegenerative and psychiatric disorders. Evaluating neuroinflammation using positron emission tomography (PET) plays an important role in the early diagnosis and determination of proper...
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A Key Mediator and Imaging Target in Alzheimer’s Disease: Unlocking the Role of Reactive Astrogliosis Through MAOB

Nam M, Na H, Lee C, Yun M

Astrocytes primarily maintain physiological brain homeostasis. However, under various pathological conditions, they can undergo morphological, transcriptomic, and functional transformations, collectively referred to as reactive astrogliosis. Recent studies have accumulated lines of...
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Radionuclide Imaging of the Neuroanatomical and Neurochemical Substrate of Cognitive Decline in Parkinson’s Disease

Booth S, Ko J

Cognitive impairment is a frequent manifestation of Parkinson’s disease (PD), resulting in decrease in patients’ quality of life and increased societal and economic burden. However, cognitive decline in PD is...
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A Review of Machine Learning Approaches for Brain Positron Emission Tomography Data Analysis

Xu K,  Kang H

Positron emission tomography (PET) imaging has moved forward the development of medical diagnostics and research across various domains, including cardiology, neurology, infection detection, and oncology. The integration of machine learning...
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Anti‑amyloid Antibody Therapies for Alzheimer’s Disease

Park K

Alzheimer’s disease (AD) is the most common cause of dementia, which is characterized by a progressive neurodegenerative disorder that is extremely difficult to treat and severely reduces quality of life....
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Clinical Performance Evaluation of an Artificial Intelligence‑Powered Amyloid Brain PET Quantification Method

Kang S, Heo M,  Chung J,  Kim D, Shin S,  Choi H,  Chung A, Ha J,  Kim H, Lee J

Abstract Purpose This study assesses the clinical performance of BTXBrain-Amyloid, an artificial intelligence-powered software for quantifying amyloid uptake in brain PET images. Methods 150 amyloid brain PET images were visually assessed by...
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