- Inhibition of chromosomal region maintenance 1 suppresses the migration and invasion of glioma cells via inactivation of the STAT3/MMP2 signaling pathway
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Shan Q, Li S, Cao Q, Yue C, Niu M, Chen X, Shi L, Li H, Gao S, Liang J, Yu R, Liu X
- KMID: 2502501
- Korean J Physiol Pharmacol.
- 2020 May;24(3):193-201.
- doi: 10.4196/kjpp.2020.24.3.193
Chromosomal region maintenance 1 (CRM1) is associated with an adverse prognosis in glioma. We previously reported that CRM1 inhibition suppressed glioma cell proliferation both in vitro and in vivo. In... -
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- Differential Effects of Tautomycetin and Its Derivatives on Protein Phosphatase Inhibition, Immunosuppressive Function and Antitumor Activity
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Niu M, Sun Y, Liu B, Tang L, Qiu R
- KMID: 2071761
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):145-151.
- doi: 10.4196/kjpp.2012.16.2.145
In the present work, we studied the structure-activity relationship (SAR) of tautomycetin (TMC) and its derivatives. Further, we demonstrated the correlation between the immunosuppressive fuction, anticancer activity and protein phosphatase... -
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- CRM1 inhibitor S109 suppresses cell proliferation and induces cell cycle arrest in renal cancer cells
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Liu X, Chong Y, Liu H, Han Y, Niu M
- KMID: 2388672
- Korean J Physiol Pharmacol.
- 2016 Mar;20(2):161-168.
- doi: 10.4196/kjpp.2016.20.2.161
Abnormal localization of tumor suppressor proteins is a common feature of renal cancer. Nuclear export of these tumor suppressor proteins is mediated by chromosome region maintenance-1 (CRM1). Here, we investigated... -
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- Sustained release of alginate hydrogel containing antimicrobial peptide Chol-37(F34-R) in vitro and its effect on wound healing in murine model of Pseudomonas aeruginosa infection
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Shi S, Dong H, Chen X, Xu S, Song Y, Li M, Yan Z, Wang X, Niu M, Zhang M, Liao C
- KMID: 2542987
- J Vet Sci.
- 2023 May;24(3):e44.
- doi: 10.4142/jvs.22319
Background: Antibiotic resistance is a significant public health concern around the globe. Antimicrobial peptides exhibit broad-spectrum and efficient antibacterial activity with an added advantage of low drug resistance. The higher water... -
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