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Case of Acute Methemoglobinemia Caused by Nitrobenzene Ingestion

Min JW, Park SY, Lee GR, Jeon YD, Jung JY, Cho YJ, Nam HW

Nitrobenzene is a poisonous agent, not commonly encountered in clinical practice, which belongs to the aniline dyes. Ingestion of nitrobenzene may cause methemoglobinemia, a condition in which the iron in...
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Time course of contact hypersensitivity to DNFB and histologic findings in mice

Cho GY, Hough W

This experiment pursued the time course of contact hypersensitivity to 2,4-dinitro-1-fluorobenzene (DNFB) and histologic changes of the cutaneous reaction in mice. The contact hypersensitivity reached a maximum 4 days after...
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Human Cytomegalovirus Induces Intercellular Adhesion Molecule-1 Expression in a Monocytic Cell Line, THP-1

Kim MS, Yi HA, Lee CH

It has been reported that inflammatory diseases such as pneumonitis, retinitis, and hepatitis are associated with human cytomegalovirus (HCMV). Intercellular adhesion molecule (ICAM)-1 is an important inflammatory mediator, helping monocytes...
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Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor

Jang JW

No abstract available.
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Percutaneous Transthoracic Cutting Needle Biopsy of Pulmonary Lesions: Comparison of the Use of 18 and 20 Gauge Needles

Kim CC, Jin GY, Han YM, Park HH, Kwon KS

  • KMID: 2334988
  • J Korean Radiol Soc.
  • 2008 May;58(5):481-485.
PURPOSE: We evaluated the usefulness of a CT guided percutaneous transthoracic cutting needle biopsy (PCNB) using a 20 gauge (G) needle for pulmonary lesions after a comparison with the use...
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Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats

Bae SH, Oh SH, Yoon SK, Park JA, Kim GD, Hur W, Choi JY, Oh IH, Yoon KH

  • KMID: 2284221
  • Gut Liver.
  • 2011 Sep;5(3):367-376.
BACKGROUND/AIMS: In the 2-acetylaminofluorene (2-AAF)/70% partial hepatectomy (PHx) model, the mechanism underlying the differentiation of activated hepatic oval cells (HOCs) into hepatocytes and bile ductile cells is unclear. We investigated...
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Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells

Lee EJ, Choi EM, Kim SR, Park JH, Kim H, Ha KS, Kim YM, Kim SS, Choe M, Kim JI, Han JA

  • KMID: 756069
  • Exp Mol Med.
  • 2007 Aug;39(4):469-476.
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis in...
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Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner

Lee ME, Kim SR, Lee S, Jung YJ, Choi SS, Kim WJ, Han JA

  • KMID: 1389733
  • Exp Mol Med.
  • 2012 Sep;44(9):536-544.
It has been proposed that the pro-inflammatory catalytic activity of cyclooxygenase-2 (COX-2) plays a key role in the aging process. However, it remains unclear whether the COX-2 activity is a...
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Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes

Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH

  • KMID: 1097104
  • Exp Mol Med.
  • 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation...
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Down-regulation of survivin in growth inhibition of hepatoma cells induced by a selective cyclooxygenase-2 inhibitor

Song IH, Kim DW, Shin KC, Shin HD, Yun SY, Kim SB, Shin JE, Kim HJ, Kim EY

BACKGROUND/AIMS: Cyclooxygenase-2 (COX-2) inhibitors reportedly inhibit the growth of hepatocellular carcinoma (HCC) via caspase-dependent or caspase-independent apoptosis, which is due to COX-2 being associated with hepatocarcinogenesis. Survivin is highly...
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