- An Angiotensin Receptor Blocker Prevents Arrhythmogenic Left Atrial Remodeling in a Rat Post Myocardial Infarction Induced Heart Failure Model
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Kim HS, No CW, Goo SH, Cha TJ
- KMID: 1777557
- J Korean Med Sci.
- 2013 May;28(5):700-708.
- doi: 10.3346/jkms.2013.28.5.700
This study investigated the role of angiotensin II receptor blocker in atrial remodeling in rats with atrial fibrillation (AF) induced by a myocardial infarction (MI). MIs were induced by a... -
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- Generation of Nitric Oxide in the Opossum Lower Esophageal Sphincter during Physiological Experimentation
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Lee SJ, Park H, Chang JH, Conklin JL
- KMID: 1110746
- Yonsei Med J.
- 2006 Apr;47(2):223-229.
- doi: 10.3349/ymj.2006.47.2.223
Lipopolysaccharide (LPS), given in vivo, modulates opossum esophageal motor functions by inducing the inducible nitric oxide synthase (iNOS), which increases nitric oxide (NO) production. Superoxide, a NO scavenger, is generated... -
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- The Protective Effects of Green Tea Extract against L-arginine Toxicity to Cultured Human Mesangial Cells
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Shin BC, Ryu HH, Chung JH, Lee BR, Kim HL
- KMID: 1778163
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S204-S209.
- doi: 10.3346/jkms.2009.24.S1.S204
The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated... -
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- Anti-Inflammatory Effect of Near-Infrared Irradiated Cell Culture Media
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Kim SG, Shin IH, Choi CH, Choe JY
- KMID: 1096928
- Korean J Lab Med.
- 2009 Aug;29(4):338-344.
- doi: 10.3343/kjlm.2009.29.4.338
BACKGROUND: Near-infrared light (NIR, 0.8-1.5 micrometer light) has been used in therapeutic devices for various injuries such as infected, ischemic and hypoxic wound. NIR-emitting technology has been developed recently in... -
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- Atelectasis Induced by Thoracotomy Causes Lung Injury during Mechanical Ventilation in Endotoxemic Rats
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Choi WI, Kwon KY, Kim JM, Quinn DA, Hales CA, Seo JW
- KMID: 1786877
- J Korean Med Sci.
- 2008 Jun;23(3):406-413.
- doi: 10.3346/jkms.2008.23.3.406
Atelectasis can impair arterial oxygenation and decrease lung compliance. However, the effects of atelectasis on endotoxemic lungs during ventilation have not been well studied. We hypothesized that ventilation at low... -
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- Hepatic Ischemic Preconditioning Provides Protection Against Distant Renal Ischemia and Reperfusion Injury in Mice
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Lee JA, Choi JW, In JH, Jung HS, Kim YS, Jeon YS, Kang YJ, Kim DW, Lim YG, Park JH, Joo JD
- KMID: 1372799
- J Korean Med Sci.
- 2012 May;27(5):547-552.
- doi: 10.3346/jkms.2012.27.5.547
We previously demonstrated that there are acute and delayed phases of renal protection against renal ischemia and reperfusion (IR) injury with renal ischemic preconditioning (IPC). This study assessed whether hepatic... -
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- Inhibition of LPS-induced cyclooxygenase 2 and nitric oxide production by transduced PEP-1-PTEN fusion protein in Raw 264.7 macrophage cells
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Lee SH, Lee YP, Kim SY, Jeong MS, Lee MJ, Kang HW, Jeong HJ, Kim DW, Sohn EJ, Jang SH, Kim YH, Kwon HJ, Cho SW, Park J, Eum WS, Choi SY
- KMID: 1072943
- Exp Mol Med.
- 2008 Dec;40(6):629-638.
- doi: 10.3858/emm.2008.40.6.629
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor. Although it is well known to have various physiological roles in cancer, its inhibitory effect on inflammation... -
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- Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells
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Park H, Park OJ, Shin J, Choi Y
- KMID: 1116197
- Exp Mol Med.
- 2005 Dec;37(6):524-532.
Receptor activator of NFkappaB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,... -
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- A new synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of the Akt/NF-kappaB pathway in BV2 microglial cells
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Lee YH, Jeon SH, Kim SH, Kim C, Lee SJ, Koh D, Lim Y, Ha K, Shin SY
- KMID: 1383799
- Exp Mol Med.
- 2012 Jun;44(6):369-377.
Microglial cells are the resident innate immune cells that sense pathogens and tissue injury in the central nervous system (CNS). Microglial activation is critical for neuroinflammatory responses. The synthetic compound... -
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