- Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase
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Iwakiri Y
- KMID: 2359812
- Clin Mol Hepatol.
- 2015 Dec;21(4):319-325.
- doi: 10.3350/cmh.2015.21.4.319
The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could... -
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- The role of nitric oxide in ocular surface diseases
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Park GS, Kwon NS, Kim YM, Kim JC
- KMID: 754298
- Korean J Ophthalmol.
- 2001 Dec;15(2):59-66.
- doi: 10.3341/kjo.2001.15.2.59
The role of nitric oxide (NO) in ocular surface diseases remains unknown. We investigated the conditions leading to increase NO generation in tears and the main sources of ocular surface... -
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- The Effects of Antioxidants and Nitric Oxide Modulators on Hepatic Ischemic-Reperfusion Injury in Rats
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Rhee JE, Jung SE, Shin SD, Suh GJ, Noh DY, Youn YK, Oh SK, Choe KJ
- KMID: 1109759
- J Korean Med Sci.
- 2002 Aug;17(4):502-506.
- doi: 10.3346/jkms.2002.17.4.502
Ischemic-reperfusion injury (IRI) is thought to be caused by oxygen radicals. Nitric oxide (NO) also has been thought to play a key role in IRI. This experiment was designed to... -
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- Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons
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Kim HJ, Im W, Kim S, Kim SH, Sung JJ, Kim M, Lee KW
- KMID: 1090960
- Exp Mol Med.
- 2007 Oct;39(5):574-582.
Familial amyotrophic lateral sclerosis (fALS) is caused by mutations in Cu/Zn-superoxide dismutase (SOD1), and SOD1 aggregation and calcium toxicity are involved in neuronal death. However, the effect of altered calcium... -
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- Arginase Inhibition Restores Peroxynitrite-Induced Endothelial Dysfunction via L-Arginine-Dependent Endothelial Nitric Oxide Synthase Phosphorylation
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Nguyen MC, Park JT, Jeon YG, Jeon BH, Hoe KL, Kim YM, Lim HK, Ryoo S
- KMID: 2427149
- Yonsei Med J.
- 2016 Nov;57(6):1329-1338.
- doi: 10.3349/ymj.2016.57.6.1329
PURPOSE: Peroxynitrite plays a critical role in vascular pathophysiology by increasing arginase activity and decreasing endothelial nitric oxide synthase (eNOS) activity. Therefore, the aims of this study were to investigate... -
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- Influence of nitric oxide on in vitro growth, survival, steroidogenesis, and apoptosis of follicle stimulating hormone stimulated buffalo (Bubalus bubalis) preantral follicles
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Dubey PK, Tripathi V, Singh RP, Sharma GT
- KMID: 1067398
- J Vet Sci.
- 2011 Sep;12(3):257-265.
- doi: 10.4142/jvs.2011.12.3.257
Effect of sodium nitroprusside (SNP), a nitric oxide (NO) donor, on in vitro survival, growth, steroidogenesis, and apoptosis of buffalo preantral follicles (PFs) was investigated. PFs (200~250 microm) were isolated... -
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- Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
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Kang YH, Yang IJ, Morgan KG, Shin HM
- KMID: 1402319
- Exp Mol Med.
- 2012 Dec;44(12):749-755.
Cinnamyl alcohol (CAL) is known as an antipyretic, and a recent study showed its vasodilatory activity without explaining the mechanism. Here we demonstrate the vasodilatory effect and the mechanism of... -
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- Phagocytosis of serum-and IgG-opsonized zymos an particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1
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Kim JS, Kwon HY, Choi WH, Jeon CY, Kim JI, Kim J, Lee JY, Kim YS, Park JB
- KMID: 1094703
- Exp Mol Med.
- 2003 Jun;35(3):211-221.
Phagocytosis of serum- and IgG-opsonized zymosan (SOZ and IOZ, respectively) particles into J774A.1 macrophages induced apoptosis of the cells, accompanied by the expression of p21(WAF1), one of cyclin-dependent protein kinase... -
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- Celastrol inhibits production of nitric oxideandproinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells
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Jung HW, Chung YS, Kim YS, Park YK
- KMID: 1091066
- Exp Mol Med.
- 2007 Dec;39(6):715-721.
Excessive production of nitric oxide (NO) and proinflammatory cytokines from activated microglia play an important role in human neurodegenerative disorders. Here, we investigated whether celastrol, which has been used as... -
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- Endothelial Dysfunction and Alteration of Nitric Oxide/ Cyclic GMP Pathway in Patients with Exercise-Induced Hypertension
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Chang HJ, Chung JH, Choi BJ, Choi TY, Choi SY, Yoon MH, Hwang GS, Shin JH, Tahk SJ, Choi BI
- KMID: 1091042
- Yonsei Med J.
- 2003 Dec;44(6):1014-1020.
- doi: 10.3349/ymj.2003.44.6.1014
The diagnostic and prognostic implication of exaggerated blood pressure response to exercise have been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbidity. Endothelial... -
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- Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat
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Sung TS, La JH, Kim TW, Yang IS
- KMID: 1059200
- J Vet Sci.
- 2006 Jun;7(2):143-150.
- doi: 10.4142/jvs.2006.7.2.143
Nitric oxide (NO) is a non-adrenergic, non-cholinergic neurotransmitter found in the enteric nervous system that plays a role in a variety of enteropathies, including inflammatory bowel disease. Alteration of nitrergic neurons has been reported... -
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