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Potential Mechanisms Underlying the Increased Excitability of the Bladder Afferent Pathways in Interstitial Cystitis/Bladder Pain Syndrome

Kim DS

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic debilitating disorder associated with lower urinary tract symptoms, including frequency, urgency, and suprapubic pain, which inconveniences the patients and seriously impairs their...
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The effect of sensorimotor stimulation for ingestion in dysphagic patients who have nonprogressive brain damage: Preliminary Study

Kang HS

  • KMID: 1401899
  • J Nurs Acad Soc.
  • 1988 Aug;18(2):211-219.
No abstract available.
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Ginger and Its Pungent Constituents Non-Competitively Inhibit Serotonin Currents on Visceral Afferent Neurons

Jin Z, Lee G, Kim S, Park CS, Park YS, Jin YH

Nausea and emesis are a major side effect and obstacle for chemotherapy in cancer patients. Employ of antiemetic drugs help to suppress chemotherapy-induced emesis in some patients but not all...
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Neurochemical Properties of Dental Primary Afferent Neurons

Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB

The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among...
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Effect of carbamazepine on tetrodotoxin-resistant Na⁺ channels in trigeminal ganglion neurons innervating to the dura

Han JE, Cho JH, Nakamura M, Lee MG, Jang IS

Migraine is a neurological disorder characterized by recurrent and disabling severe headaches. Although several anticonvulsant drugs that block voltage-dependent Na⁺ channels are widely used for migraine, far less is known...
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The Localization of Efferent and Afferent Neurons Innervating the Rat Thymus Using the Neural Tracers

Lee CH, Jang KS, Kim HT, Lee MS

  • KMID: 2092642
  • Korean J Anat.
  • 1998 Feb;31(1):71-80.
The localizations of efferent and afferent neurons were observed following injection of neural tracers, cholera toxin B subunit (CTB) and wheat germ agglutinin-horseradish peroxidase (WGA-HRP) into the rat thymus with...
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Neurologic Mechanisms Underlying Voiding Dysfunction due to Prostatitis in a Rat Model of Nonbacterial Prostatic Inflammation

Park JS, Jin MH, Hong CH

PURPOSE: The neurological molecular mechanisms underlying the voiding dysfunction associated with nonbacterial chronic prostatitis/chronic pelvic pain syndrome remain poorly understood. In this study, we assessed whether prostate inflammation activated bladder...
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Sympathetic Excitation of Afferent Neurons within Dorsal Root Ganglia in a Rat Model of Sympathetically Medicated Pain

Leem JW, Kang MJ, Paik KS, Nam YT

  • KMID: 2104731
  • J Korean Pain Soc.
  • 1996 Jun;9(1):26-38.
In a normal state, sympathetic efferent activity does not elicit discharges of sensory neurons, whereas it becomes associated with and excites sensory neurons in a pathophysiological state such as injury...
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Change of Bladder Afferent Neuron after Intravesical Electrical Stimulation

Hong CH, Kim YS, Kim JH, Noh JY, Ko HK, Kim CS, Han SW

  • KMID: 2293338
  • Korean J Urol.
  • 2003 May;44(5):468-472.
PURPOSE: There have been reports on the clinical benefits of intravesical electrical stimulation (IVES) in patients with an increased residual urine or reduced bladder capacity. However, studies on the underlying...
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Response to Capsaicin and Changes in Sodium Currents in Dorsal Root Ganglion Neurons of Neuropathic Rats

Leem JG, Lim TH, Lee JR, Kim JU, Hwang JH, Shin KI

BACKGROUND: Allodynia, one of the most debilitating symptoms of neuropathic pain syndromes, can be defined as `pain due to a stimulus that does not normally provoke pain'. Subsets of dorsal...
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Update on dentin hypersensitivity: with the focus on hydrodynamic theory and mechanosensitive ion channels

Won J, Oh SB

Dentin hypersensitivity is an abrupt intense pain caused by innocuous stimuli to exposed dentinal tubules. Mechanosensitive ion channels have been assessed in dental primary afferent neurons and odontoblasts to explain...
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Changes in Gastrointestinal Physiology in Obese Patients

Yun SH, Park JK, Shin JE, Diet, Obesity, and Metabolism Research Group of Korean Society of Neurogastroenterology and Motility

Obesity is a prevalent disease with significant morbidity and mortality. It is a state of chronic low-grade inflammation due to excess body fat. Weight homeostasis is maintained through changes in...
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Voltage-Dependent Potassium Currents in Acutely Isolated Rat Medial Vestibular Nucleus Neurons

Chun SW, Lee JS, Park BR

  • KMID: 1874203
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Sep;42(9):1081-1088.
BACKGROUND AND OBJECTIVES: Medial vestibular nucleus (MVN) neurons are second-order afferent neurons that are involved in the reflex control of the head and eyes. Results from several studies utilizing the...
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Sensory Neuronal Change after Intravesical Electrical Stimulation in Spinailized Rat

Hong CH, Kim JH, Noh JY, Gil YC, Lee HY, Lee WH, Han SW

The clinical benefits of intravesical electrical stimulation (IVES) in patients with increased residual urine or reduced bladder capacity have been reported. However, studies on the underlying mechanism of IVES has...
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Vanilloid Receptor Type-1 Immunoreactivities in the Mouse Myenteric Plexus: Immunohistochemical and Electrophysiological Study

Jun JY, Yang ES, Kim KH, Chang IY

  • KMID: 1517133
  • Korean J Phys Anthropol.
  • 2004 Mar;17(1):45-53.
The vanilloid receptor type-1 (VR1) is a nonselective cation channel activated by capsaicin and can be act as mediator of chemical and physical stimuli that elicit pain. The presence of...
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Isolation of Voltage Dependent Calcium Current in Chick Inner Hair Cell

Lee SH, Shin MC, Ahn TH, Kim KY, Kim K, Min HJ, Park CW

BACKGROUND AND OBJECTIVES: Voltage dependent calcium channel (VDCC) mediates calcium ion influx and controls neurotransmitter release in excitable cells. Hair cells in vertebrates cochlea are known to express L-type VDCC....
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Mechanism of Interdigestive Migrating Motor Complex

Takahashi

  • KMID: 2325917
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):246-257.
Migrating motor complex (MMC) is well characterized by the appearance of gastrointestinal contractions in the interdigestive state. This review article discussed the mechanism of gastrointestinal MMC. Luminal administration of 5-hydroxytryptamine...
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Immunohistochemical Study of Neuropeptides in Feline Vagal Afferent Neurons

Cho JI, Kim YM, Park JW, Han CJ

  • KMID: 2074335
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Jan;42(1):88-96.
BACKGROUND AND OBJECTIVES: Nodose ganglion (NG) of the vagus nerve is well known as a sensory ganglion mediated by many neurotransmitters. These neurotransmitters are substance P (SP), calcitonin gene-related peptide...
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Early Experience of Intravesical Capsaicin for Treatment of Detrusor Hyperreflexia in Patients with Spinal Cord Injury

Kim HG, Park WH, Choi YC, So JG, Park BJ, Kim DY, Lim YS, Shim HB

PURPOSE: The clinical and urodynamic effects of intravesical capsaicin, a neurotoxic substance causing a reversible suppression of unmyelinated C fiber afferent neuronal activity, were investigated for treatment of detrusor hyperreflexia...
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Tenelectrodes: a New Stimulator for Inching Technique in the Diagnosis of Carpal Tunnel Syndrome

Kang YK, Kim DH, Lee SH, Hwang M, Han MS

This study was designed to evaluate the usefulness of a new multielectrode stimulator, TenElectrodes, in the diagnosis and localization of the compression site in the wrists of carpal tunnel syndrome...
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