- Anti-Allodynic Effects of Levodopa in Neuropathic Rats
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Park HJ, Joo HS, Kim YH, Kwon OK, Lee J, Kim ES, Moon DE
- KMID: 1503893
- Yonsei Med J.
- 2013 Mar;54(2):330-335.
- doi: 10.3349/ymj.2013.54.2.330
PURPOSE: Levodopa is the most effective anti-Parkinsonian agent. It has also been known to exhibit analgesic properties in laboratory and clinical settings. However, studies evaluating its effects on neuropathic pain... -
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- Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats
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Huang LJ, Yoon MH, Choi JI, Kim WM, Lee HG, Kim YO
- KMID: 1779610
- Yonsei Med J.
- 2010 Jan;51(1):82-87.
- doi: 10.3349/ymj.2010.51.1.82
PURPOSE: The inhibition of phosphodiesterase 5 produces an antinociception through the increase of cyclic guanosine monophosphate (cGMP), and increasing cGMP levels enhance the release of gamma-aminobutyric acid (GABA). Furthermore, this... -
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- Antinociceptive Effects of Amiloride and Benzamil in Neuropathic Pain Model Rats
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Jeong S, Lee SH, Kim YO, Yoon MH
- KMID: 1793032
- J Korean Med Sci.
- 2013 Aug;28(8):1238-1243.
- doi: 10.3346/jkms.2013.28.8.1238
Amiloride and benzamil showed antinocicepitve effects in several pain models through the inhibition of acid sensing ion channels (ASICs). However, their role in neuropathic pain has not been investigated. In... -
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- Intrathecal Gabapentin Increases Interleukin-10 Expression and Inhibits Pro-Inflammatory Cytokine in a Rat Model of Neuropathic Pain
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Lee BS, Jun IG, Kim SH, Park JY
- KMID: 1429210
- J Korean Med Sci.
- 2013 Feb;28(2):308-314.
- doi: 10.3346/jkms.2013.28.2.308
We examined the possible anti-inflammatory mechanisms of gabapentin in the attenuation of neuropathic pain and the interaction between the anti-allodynic effects of gabapentin and interleukin-10 (IL-10) expression in a rat... -
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- Protective Effects of Gabapentin on Allodynia and alpha2delta1-Subunit of Voltage-dependent Calcium Channel in Spinal Nerve-Ligated Rats
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Hahm TS, Ahn HJ, Bae CD, Kim HS, Lim SW, Cho HS, Lee SM, Sim WS, Kim JA, Gwak MS, Choi SJ
- KMID: 1794421
- J Korean Med Sci.
- 2009 Feb;24(1):146-151.
- doi: 10.3346/jkms.2009.24.1.146
This study was designed to determine whether early gabapentin treatment has a protective analgesic effect on neuropathic pain and compared its effect to the late treatment in a rat neuropathic... -
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