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Effect of Basic Fibroblast Growth Factor-Saporin (bFGF-SAP) Conjugate on Bovine Choriocapillary Endothelial Cells

Kim YH, Kim HS, Yoo JS

We evaluated the effect of a basic fibroblast growth factor (bFGF) and saporin conjugate (bFGF-SAP) on proliferation, migration and tubule formation in bovine choriocapillary endothelial cells (BCECs). Cell proliferation and...
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Cryptotanshinone but not tanshinone IIA inhibits angiogenesisin vitro

Hur JM, Shim JS, Jung HJ, Kwon HJ

  • KMID: 755752
  • Exp Mol Med.
  • 2005 Apr;37(2):133-137.
In the course of screening of angiogenesis inhibitor from natural products, cryptotanshinone from Salvia miltiorrhiza was isolated as a potent small molecule inhibitor of angiogenesis. Cryptotanshinone inhibits bFGF-induced angiogenesis of...
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KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Yi EY, Park SY, Song HS, Son MJ, Yi KY, Yoo SE, Kim YJ

  • KMID: 1098084
  • Exp Mol Med.
  • 2006 Oct;38(5):502-508.
Angiogenesis is considered to be an integral process to the growth and spread of solid tumors. Anti-angiogenesis therapy recently has been found to be one of the most promising anti-cancer...
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A serum-stable branched dimeric anti-VEGF peptide blocks tumor growth via anti-angiogenic activity

Kim JW, Kim TD, Hong BS, Kim OY, Yoon WH, Chae CB, Gho YS

Angiogenesis is critical and indispensable for tumor progression. Since VEGF is known to play a central role in angiogenesis, the disruption of VEGF-VEGF receptor system is a promising target for...
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Purification and characterization of recombinant murine endostatin in E. coli

You WK, So SH, Lee H, Park SY, Yoon MR, Chang SI, Kim HK, Joe YA, Hong YK, Chung SI

  • KMID: 1029927
  • Exp Mol Med.
  • 1999 Dec;31(4):197-202.
Endostatin, a carboxyl-terminal fragment of collagen XVIII is known as an anti-angiogenic agent, that specifically inhibits the proliferation of endothelial cell and the growth of several primary tumor....
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Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in mice

Sozmen M, Devrim AK, Tunca R, Bayezit M, Dag S, Essiz D

The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B1 (FB1) in BALB/c mice. The mice were divided into six groups...
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Early Sustained Injections of Erythropoietin Improve Angiogenesis and Restoration of Perfusion in the Ischemic Mouse Hindlimb

Ahn S, Min SK, Min SI, Suh JH, Kim SJ, Ha J

This study was conducted to investigate the effects of erythropoietin (Epo) on both acute and chronic limb ischemia (ALI and CLI) and to evaluate the differences in mechanisms according to...
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