- Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat
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Jang JJ, Cho KJ, Lee YS, Bae JH
- KMID: 1421512
- J Korean Med Sci.
- 1991 Mar;6(1):31-36.
- doi: 10.3346/jkms.1991.6.1.31
The modifying potential of capsaicin (CAP) on lesion development was examined in a rat multiorgan carcinogenesis model. Groups 1 and 2 were treated sequentially with diethylnitrosamine (DEN) (100 mg/kg, ip,... -
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- Chemoprevention of Mammary, Cervix and Nervous system Carcinogenesis in Animals using Cultured Panax ginseng Drugs and Preliminary Clinical Trials in Patients with Precancerous Lesions of the Esophagus and Endometrium
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Bespalov V, Alexandrov VA, Limarenko , Voytenkov , Okulov VB, Kabulov MK, Peresunko , Slepyan LI, Davydov VV
- KMID: 1721174
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S42-S53.
- doi: 10.3346/jkms.2001.16.S.S42
The anticarcinogenic effects and mechanisms of the biotechnological drugs of Panax ginseng C.A. Meyer cultivated in Russia, bioginseng, panaxel and panaxel- 5, were studied. Bioginseng was produced from a tissue... -
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- Neoplastic Paneth cells in the experimental murine carcinoma of the small intestine
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Kim WH, Kim YI
- KMID: 1421501
- J Korean Med Sci.
- 1990 Dec;5(4):197-203.
- doi: 10.3346/jkms.1990.5.4.197
The purpose of this study is to elucidate the participation of Paneth cells in experimentally induced adenocarcinoma of the intestine. The rats were fed with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) dissolved in drinking... -
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- Inhibitory effects of biochanin A on mouse lung tumor induced by benzo(a)pyrene
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Lee YS, Seo JS, Chung HT, Jang JJ
- KMID: 1421874
- J Korean Med Sci.
- 1991 Dec;6(4):325-328.
- doi: 10.3346/jkms.1991.6.4.325
Biochanin A, an isoflavone compound, is reported to have an inhibitory effect on benzo(a)pyrene [B(a)P] metabolism. We examined the modifying effect of biochanin A on in vivo carcinogenesis using a... -
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- Ossification of the N-methyl-N'-nitro-N-nitrosoguanidine-induced small intestine adenocarcinomas in rats
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Kim WH, Kim YI
- KMID: 1421871
- J Korean Med Sci.
- 1991 Dec;6(4):308-312.
- doi: 10.3346/jkms.1991.6.4.308
Eighty rats out of 233 developed malignant tumors in the stomach and small intestine by administration of 100 micrograms/ml N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in drinking water for 28 weeks. Fifteen lesions (30%)... -
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- Lung adenoma development and NK activity in mice treated with multiple carcinogens
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Lee YS, Seo JS, Chung HT, Cho KJ, Jang JJ
- KMID: 1421882
- J Korean Med Sci.
- 1992 Mar;7(1):1-5.
- doi: 10.3346/jkms.1992.7.1.1
A wide-spectrum initiation model was investigated in mice. Sequential treatments with diethylnitrosamine, urethane and N-methylnitrosourea, with or without a promoter, phenobarbital, resulted in tumor formation in the lungs in... -
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- Occupational Hepatic Disorders in Korea
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Kim HR, Kim TW
- KMID: 1714065
- J Korean Med Sci.
- 2010 Dec;25(Suppl):S36-S40.
- doi: 10.3346/jkms.2010.25.S.S36
Occupational hepatic disorders are classified into toxic hepatitis, viral hepatitis, and chemical-induced malignancy in Korea. Toxic hepatitis cases were reported in workers who were exposed to dimethylformamide, dimethylacetamide, or trichloroethylene.... -
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- Testosterone therapy in men with testosterone deficiency: Are we beyond the point of no return?
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Traish A
- KMID: 2451397
- Investig Clin Urol.
- 2016 Nov;57(6):384-400.
- doi: 10.4111/icu.2016.57.6.384
Although testosterone therapy in men with testosterone deficiency was introduced in the early 1940s, utilization of this effective treatment approach in hypogonadal men is met with considerable skepticism and resistance.... -
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- Health Effects of Chronic Arsenic Exposure
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Hong YS, Song KH, Chung JY
- KMID: 2381428
- J Prev Med Public Health.
- 2014 Sep;47(5):245-252.
- doi: 10.3961/jpmph.14.035
Arsenic is a unique element with distinct physical characteristics and toxicity whose importance in public health is well recognized. The toxicity of arsenic varies across its different forms. While the... -
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- Molecular biomarkers of occupational lung cancer
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Talaska G, Roh J, Zhou Q
- KMID: 699868
- Yonsei Med J.
- 1996 Feb;37(1):1-18.
- doi: 10.3349/ymj.1996.37.1.1
Occupational exposures to certain metals, hydrocarbons and ionizing radiation are associated with increased lung cancer in workers; because these exposures continue, lung cancer remains an important problem in industrialized nations.... -
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- Occupational Respiratory Cancer in Korea
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Lee HE, Kim HR
- KMID: 1714073
- J Korean Med Sci.
- 2010 Dec;25(Suppl):S94-S98.
- doi: 10.3346/jkms.2010.25.S.S94
Malignant mesothelioma and lung cancer are representative examples of occupational cancer. Lung cancer is the leading cause of cancer death, and the incidence of malignant mesothelioma is expected to increase... -
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- Suppression of hepatic tumor growth and metastasis by metronomic therapy in a rat model of hepatocellular carcinoma
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Jang JW, Park ST, Kwon JH, You CR, Choi JY, Jung CK, Bae SH, Yoon SK
- KMID: 1009970
- Exp Mol Med.
- 2011 May;43(5):305-312.
- doi: 10.3858/emm.2011.43.5.033
Although continuous low-dose (metronomic [MET]) therapy exerts anti-cancer efficacy in various cancer models, the effect of long-term MET therapy for hepatocellular carcinoma (HCC) remains unknown. This study assessed the long-term... -
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- Açaà Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
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Choi YJ, Choi YJ, Kim N, Nam RH, Lee S, Lee HS, Lee HN, Surh YJ, Lee DH
- KMID: 2412191
- Gut Liver.
- 2017 Mar;11(2):243-252.
- doi: 10.5009/gnl16068
BACKGROUND/AIMS: The aim of this study was to investigate the protective effect of açaà against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer development. METHODS: The effect of açaà on tumorigenesis was... -
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- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
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Wang Z, Jin H, Xu R, Mei Q, Fan D
- KMID: 1009393
- Exp Mol Med.
- 2009 Oct;41(10):717-727.
- doi: 10.3858/emm.2009.41.10.078
Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation... -
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- Differences in risk for type 1 and type 2 ovarian cancer in a large cancer screening trial
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Terada KY, Ahn HJ, Kessel B
- KMID: 2363319
- J Gynecol Oncol.
- 2016 May;27(3):e25.
- doi: 10.3802/jgo.2016.27.e25
OBJECTIVE: To investigate the role of previous gynecologic surgery, hormone use, and use of non-steroidal anti-inflammatory drugs on the risk of type 1 and type 2 ovarian cancer. METHODS: We utilized... -
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- Expression and Localization of the Transforming Growth Factor-beta Type I receptor and Smads in Preneoplastic Lesions during Chemical Hepatocarcinogenesis in Rats
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Park DY, Lee CH, Sol MY, Suh KS, Yoon SY, Kim JW
- KMID: 648902
- J Korean Med Sci.
- 2003 Aug;18(4):510-519.
- doi: 10.3346/jkms.2003.18.4.510
Little is known about the involvement of Smad-related molecules in the regulation of the Transforming Growth Factor (TGF)-beta signaling pathway during hepatocarcinogenesis, particularly with respect to preneoplastic lesions of a... -
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- Isoflavone-deprived soy peptide suppresses mammary tumorigenesis by inducing apoptosis
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Park K, Choi K, Kim H, Kim K, Lee MH, Lee JH, Kim Rim JC
- KMID: 756229
- Exp Mol Med.
- 2009 Jun;41(6):371-380.
- doi: 10.3858/emm.2009.41.6.042
During carcinogenesis, NF-kappaB mediates processes associated with deregulation of the normal control of proliferation, angiogenesis, and metastasis. Thus, suppression of NF-kappaB has been linked with chemoprevention of cancer. Accumulating findings... -
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- Intraductal Carcinoma of the Prostate Gland: Recent Advances
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Divatia MK, Ro JY
- KMID: 2374148
- Yonsei Med J.
- 2016 Sep;57(5):1054-1062.
- doi: 10.3349/ymj.2016.57.5.1054
Intraductal carcinoma of the prostate (IDC-P) is characterized by prostatic carcinoma involving ducts and/or acini. The presence of IDC-P is usually associated with a high-grade Gleason score, large tumor volume,... -
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- The Scope and Specific Criteria of Compensation for Occupational Diseases in Korea
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Song J, Kim I, Choi BS
- KMID: 1791997
- J Korean Med Sci.
- 2014 Jun;29(Suppl):S32-S39.
- doi: 10.3346/jkms.2014.29.S.S32
The range of diseases covered by workers' compensation is constantly expanding. However, new regulations are required for the recognition of occupational diseases (ODs) because OD types evolve with changes in... -
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- Compensation for Occupational Cancer
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Kim I, Kim EA, Kim JY
- KMID: 1791998
- J Korean Med Sci.
- 2014 Jun;29(Suppl):S40-S46.
- doi: 10.3346/jkms.2014.29.S.S40
The legal scope and criteria for occupational cancer in Korea was out of date. The aim of this study was to review the current criteria for occupational cancer and amend... -
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