- What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer?
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Lee SK
- KMID: 1730923
- Korean J Gastroenterol.
- 2014 Feb;63(2):137-139.
- doi: 10.4166/kjg.2014.63.2.137
No abstract available. -
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- Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma
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Subramani , Lopez-Valdez R, Salcido A, Boopalan T, Arumugam A, Nandy S, Lakshmanaswamy R
- KMID: 2155382
- Exp Mol Med.
- 2014 Oct;46(10):e117.
- doi: 10.1038/emm.2014.61
Pancreatic cancer is the only major cancer with very low survival rates (1%). It is the fourth leading cause of cancer-related death. Hyperactivated growth hormone receptor (GHR) levels have been... -
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- Clinical significance of molecular genetic changes in sporadic invasive pituitary adenomas
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Nam DH, Song SY, Park KS, Kim MH, Suh YL, Lee JI, Kim JS, Hong SC, Shin HJ, Park K, Eoh W, Kim JH
- KMID: 938873
- Exp Mol Med.
- 2001 Sep;33(3):111-116.
Several molecular and genetic changes have been found in pituitary adenomas. We looked for correlations between these changes and the degree of invasiveness of the tumors. The invasiveness of 11... -
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- Pathologic findings at risk-reducing salpingo-oophorectomy (RRSO) in germline BRCA mutation carriers with breast cancer: significance of bilateral RRSO at the optimal age in germline BRCA mutation carriers
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Lee YJ, Lee SW, Kim KR, Jung KH, Lee JW, Kim YM
- KMID: 2413850
- J Gynecol Oncol.
- 2017 Jan;28(1):e3.
- doi: 10.3802/jgo.2017.28.e3
OBJECTIVE: Most BRCA1/2 carriers do not undergo risk-reducing salpingo-oophorectomy (RRSO) by the recommended age. This study aimed to find the incidence of precursor lesions and cancer after RRSO. METHODS: We retrospectively... -
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- Integrative epigenomic and genomic analysis of malignant pheochromocytoma
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Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C
- KMID: 1104209
- Exp Mol Med.
- 2010 Jul;42(7):484-502.
- doi: 10.3858/emm.2010.42.7.050
Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to... -
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- Gene Expression Profiling of Hepatocellular Carcinoma Derived Cancer Stem Like Cell under Hypoxia
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Choi SH, Lee SW, Ok M, Kim KS, Kim S, Ahn SH
- KMID: 2418927
- Yonsei Med J.
- 2017 Sep;58(5):925-933.
- doi: 10.3349/ymj.2017.58.5.925
PURPOSE: Cancer stem like cells (CSCs), with unlimited self-renewal potential and other stem cell characteristics, occur in several cancers including hepatocellular carcinoma (HCC). Although CSCs can initiate tumors, malignant proliferation,... -
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- Clinical Significance of Microsatellite Instability in Sporadic Epithelial Ovarian Tumors
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Yoon BS, Kim YT, Kim JH, Kim SW, Nam EJ, Cho NH, Kim JW, Kim S
- KMID: 1084501
- Yonsei Med J.
- 2008 Apr;49(2):272-278.
- doi: 10.3349/ymj.2008.49.2.272
PURPOSE: We evaluated the expression of microsatellite instability (MSI) in sporadic ovarian tumors using 5 standard and 9 new MSI markers to determine the clinical significance of MSI in sporadic... -
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- A known expressed sequence tag, BM742401, is a potent lincRNA inhibiting cancer metastasis
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Park SM, Park SJ, Kim HJ, Kwon OH, Kang TW, Sohn HA, Kim SK, Moo Noh S, Song KS, Jang SJ, Sung Kim Y, Kim SY
- KMID: 2154250
- Exp Mol Med.
- 2013 Jul;45(7):e31.
Long intergenic non-coding RNAs (lincRNAs) have historically been ignored in cancer biology. However, thousands of lincRNAs have been identified in mammals using recently developed genomic tools, including microarray and high-throughput... -
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- Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells
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Park HY, Jeon YK, Shin HJ, Kim IJ, Kang HC, Jeong SJ, Chung DH, Lee CW
- KMID: 1094660
- Exp Mol Med.
- 2007 Apr;39(2):195-204.
The BubR1 mitotic-checkpoint protein monitors proper attachment of microtubules to kinetochores, and links regulation of chromosome-spindle attachment to mitotic-checkpoint signaling. Thus, disruption of BubR1 activity results in a loss of... -
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- Clinical Implications of Microsatellite Instability in T1 Colorectal Cancer
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Kang J, Lee HW, Kim IK, Kim NK, Sohn SK, Lee KY
- KMID: 2352804
- Yonsei Med J.
- 2015 Jan;56(1):175-181.
- doi: 10.3349/ymj.2015.56.1.175
PURPOSE: The estimation of regional lymph node metastasis (LNM) risk in T1 colorectal cancer is based on histologic examination and imaging of the primary tumor. High-frequency microsatellite instability (MSI-H) is... -
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- Clinicopathologic Impacts of Poorly Differentiated Cluster-Based Grading System in Colorectal Carcinoma
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Kim JW, Shin MK, Kim BC
- KMID: 2155443
- J Korean Med Sci.
- 2015 Jan;30(1):16-23.
- doi: 10.3346/jkms.2015.30.1.16
Differentiation-based histologic grading of colorectal carcinoma (CRC) is widely used, but its clinical impact is limited by insufficient prognostic value, interobserver disagreement, and the difficulty of its application to CRC... -
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