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An Experimental Study on the Intraarterial cis-platinum Chemotherapeutic Response of Musculoskeletal Tumor Using MR Imaging and Digital Subtraction Angiography

Kim IO, Cho JY, Choo SW, Shin YM, Kim JS, Kim CW, Kim CJ

  • KMID: 2201532
  • J Korean Radiol Soc.
  • 1997 May;36(5):891-898.
PURPOSE: To determine MRI features of tumor response in the early phase of preoperative chemotherapy in malignant tumors after intraarterial chemotherapy of VX-2 tumor in the rabbit thigh. MATERIALS AND METHODS:...
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Anticarcinogenic Effect of Red Ginseng on the Development of Liver Cancer Induced by Diethylnitrosamine in Rats

Wu XG, Zhu DH, Li X

Anticarcinogenic effect of red ginseng (Panax ginseng C.A. Meyer cultivated in JiLin, China) on the development of liver cancer induced by diethylnitrosamine (DEN) in rats was studied, especially in preventive...
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Intratumoral Vascularity of Experimentally Induced VX2 Carcinoma: Comparison of Power Doppler Sonography and Microangiography

Park KS, Won HJ, Seo JB, Kim TK, Han JK, Choi BI

  • KMID: 1945598
  • J Korean Radiol Soc.
  • 1997 Jul;37(1):51-57.
PURPOSE: To evaluate the usefulness and limitations of power Doppler sonography in determining the tumor vascularity. MATERIALS AND METHODS: Power Doppler sonography was performed on VX2 carcinomas present in rabbit thighs,...
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Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat

Jang JJ, Cho KJ, Lee YS, Bae JH

The modifying potential of capsaicin (CAP) on lesion development was examined in a rat multiorgan carcinogenesis model. Groups 1 and 2 were treated sequentially with diethylnitrosamine (DEN) (100 mg/kg, ip,...
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Factors Influencing the Pathogenicity of Entamoeba Histolytica

Soh CT

In summarizing the results of the experimental studies up to the present, it is conjectured that the pathogenicity of Entamoeba histolytica or establishment of amoebiasis is not unique but differs...
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Surface Properties of Cell Membrane in Early Stage of Transformed Cell -I. Early Detection of Transformed Cell by Concanavalin A; II. Properties of Plasma Membrane of Transformed Rat Liver Cell Induced by 3'-Me DAB

Kim YS, Cho MY

The present study was designed in order to investigate the lectin induced cytoagglutination properties of normal and transformed cells and surface alterations in the early stage of the transformed cells...
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Tumor Vascularity of Experimentally Induced VX2 Carcinoma in the Rabbit Thigh: Evaluation with Enhanced Power Doppler Sonography and DSA Correlated with Histopathologic Findings

Kim YH, Han JK, Chung JW, Lee KH, Kim SH, Kim SJ, Choi BI, Chang KH

PURPOSE: To describe findings of enhanced power Doppler sonography and DSA in experimentally induced VX2 carcinomas in rabbit thigh and to correlate the imaging findings with the histopathologic features. MATERIALS AND...
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Chemoprevention of Mammary, Cervix and Nervous system Carcinogenesis in Animals using Cultured Panax ginseng Drugs and Preliminary Clinical Trials in Patients with Precancerous Lesions of the Esophagus and Endometrium

Bespalov V, Alexandrov VA, Limarenko , Voytenkov , Okulov VB, Kabulov MK, Peresunko , Slepyan LI, Davydov VV

The anticarcinogenic effects and mechanisms of the biotechnological drugs of Panax ginseng C.A. Meyer cultivated in Russia, bioginseng, panaxel and panaxel- 5, were studied. Bioginseng was produced from a tissue...
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Administration of multiple cytokine genes with anti-tumor activity inhibits both tumor incidence and tumor growth

Jang HS, Cho TH, Jang YS, Choung PH

The finding of reporter gene expression in muscle cells after intramuscular injection of a reporter gene containing DNA has suggested that injection of a certain gene in its...
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RE: Differential Diagnosis of Axillary Inflammatory and Metastatic Lymph Nodes in Rabbit Models by Using Diffusion-Weighted Imaging: Compared with Conventional Magnetic Resonance Imaging

Sivrioglu , Sonmez G, Incedayi M, Saglam M

No abstract available.
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Expression of Inducible Nitric Oxide Synthase Is Increased in Rat Barrett's Esophagus Induced by Duodenal Contents Reflux

Bae JD, Jung KH, Ahn WS, Bae SH, Jang TJ

Barrett's esophagus is a premalignant condition of esophageal adenocarcinoma. Inducible nitric oxide synthase (iNOS) is induced by cytokines and can generate locally high concentrations of nitric oxide (NO), whose metabolites...
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Cancer Chemoprevention by Ginseng in Mouse Liver and Other Organs

Nishino H, Tokuda H, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Bu P, Takayasu J, Onozuka M, Masuda M, Satomi Y, Konoshima , Kishi N, Baba M, Okada Y, Okuyama T

Oral administration of red ginseng extracts (1% in diet for 40 weeks) resulted in the significant suppression of spontaneous liver tumor formation in C3H/He male mice. Average number of tumors...
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Evaluation of Tumor Angiogenesis with a Second-Generation US Contrast Medium in a Rat Breast Tumor Model

Ko EY, Lee SH, Kim HH, Kim SM, Shin MJ, Kim N, Gong G

OBJECTIVE: Tumor angiogenesis is an important factor for tumor growth, treatment response and prognosis. Noninvasive imaging methods for the evaluation of tumor angiogenesis have been studied, but a method for...
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Transferrin receptor expression of the hyperplastic lesions of hepatocyte in experimental hepatocarcinogenesis

Park CI, Park YN, Jung WH

Transferrin receptor (TR) performs the major function of binding and internalizing its specific iron-loaded ligand, transferrin, and its expression is closely linked to the proliferation status of the cell. This...
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Expression of ErbB Receptor Proteins and TGF-alpha during Diethylnitrosamine-induced Hepatocarcinogenesis in the Rat Liver

Lee TY, Kim KT, Han SY

  • KMID: 760707
  • Korean J Hepatol.
  • 2007 Mar;13(1):70-80.
BACKGROUND/AIMS: ErbB receptor proteins are transmembrane tyrosine kinase receptors; when they are activated by interaction with ligands, they generate diverse cellular responses, especially during lesion development and progression to...
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Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis

Ha WS, Kim CK, Song SH, Kang CB

  • KMID: 1103507
  • J Vet Sci.
  • 2001 Apr;2(1):53-58.
With the aim of establishing bio-indices for the development of multistep hepatotumorigenesis, rats were fed water containing 0.01% diethylnitrosamine (DEN) ad libitum for 13 weeks. This treatment with DEN only...
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LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression

Kim JE, Kim HS, Shin YJ, Lee CS, Won C, Lee SA, Lee JW, Kim Y, Kang JS, Ye SK, Chung MH

Tumor migration/invasion is the main cause of tumor progression and STAT3 is needed to enhance tumor migration/invasion by up-regulating MMP-9. Thus, agents that inhibit STAT3 activation may be used as...
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Impact of Energy and Access Methods on Extrahepatic Tumor Spreading and the Ablation Zone: An Ex vivo Experiment Using a Subcapsular Tumor Model

Kim JS, Ko Y, Kwon H, Kim M, Lee JK

OBJECTIVE: To evaluate the impact of energy and access methods on extrahepatic tumor spreading and the ablation zone in an ex vivo subcapsular tumor mimic model with a risk of...
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Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway

Jeong JS, Kim IH, Lee HJ, Choi YC

  • KMID: 755010
  • Exp Mol Med.
  • 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer...
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Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride

Qin G, Ning Y, Su J, Shinozuka , Lotlikar P

  • KMID: 755007
  • Exp Mol Med.
  • 1998 Dec;30(4):186-191.
The effect of carbon tetrachloride (CCl4) on aflatoxin B1 (AFB1)-induced enzyme altered hepatic foci has been examined in young male Fischer rats given AIN-76A diet. A single i.p. dose of...
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