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Cerebral Salt Wasting Treated with Fludrocortisone in a 17-Year-Old Boy

Choi MJ, Oh YS, Park SJ, Kim JH, Shin JI

Cerebral salt wasting is characterized by inappropriate natriuresis and volume contraction with associated cerebral pathology. It is distinct from the syndrome of inappropriate antidiuretic hormone secretion, which is characterized by...
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Nitric Oxide in the Kidney: Its Physiological Role and Pathophysiological Implications

Lee JU

Nitric oxide has been implicated in many physiologic processes that influence both acute and long-term control of kidney function. Its net effect in the kidney is to promote natriuresis and...
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Effects of Intrarenal Arterial Infusion of Arginine Vasopressin on the Renal Function and Renin Release in Conscious Rabbits

Kim HS, Cui X, Lee SJ, Kim SH, Cho KW

  • KMID: 2079113
  • Korean J Nephrol.
  • 2000 Jul;19(4):637-648.
Arginine vasopressin(AVP) released from the posterior pituitary gland is well known to cause an increase in blood pressure, antidiuresis, natriuresis and inhibition of renin secretion. However, the mechanism involved in...
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Polyuria and Natriuresis of Unknown Origin Accompanied with Hypotension in Critically Ill Patients

Chun KJ, Lee DK, Baek HJ, Kim SW, Jung HH

  • KMID: 2307163
  • Korean J Nephrol.
  • 2009 Nov;28(6):552-558.
PURPOSE: We observed excessive renal excretion of salt and water, without underlying renal diseases or definite causes, accompanied with severe hypotension in critically ill patients. This study investigates the clinical...
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Pathogenesis of Postobstructive Diuresis: Role of Aquaporin Water Channels, Sodium Transporters and Natriuretic Peptide System in the Kidney in Rats

Kim SW

  • KMID: 2052260
  • Electrolyte Blood Press.
  • 2005 Nov;3(2):82-90.
Although the obstruction is potentially reversible with treatment, marked and sometimes prolonged diuresis and natriuresis associated with an impaired ability to concentrate the urine may follow relief of the obstruction....
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Natriuresis induced by intracerebroventricular diazepam in rabbits

Koh JT, Kook YJ

  • KMID: 2071535
  • Korean J Physiol Pharmacol.
  • 1998 Oct;2(5):555-563.
The renal function is under regulatory influence of central nervous system (CNS), in which various neurotransmitter and neuromodulator systems take part. However, a possible role of central GABA-benzodiazepine system on the central regulation...
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Studies on the Mechanism of Renal Action of Centrally-administered TFMPP in Rabbits

Lim YC, Koh JT, Kim HJ, Lee S, Jang AS, Yang SW, Seo JP, Choi JB, Kook YJ

  • KMID: 1990073
  • Korean J Nephrol.
  • 1999 Mar;18(2):211-218.
It has been known that central tryptaminergic system is closely related with the regulation of renal function, and that central 5-HT1 receptors mediate diuresis and natriuresis, whereas central 5-HT2 and...
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Blood Pressure Regulation by Vasoactive Peptide Genes: Transgenic And Knockout Animal Models

Ahn D

  • KMID: 2134792
  • Electrolyte Blood Press.
  • 2005 Mar;3(1):14-23.
Hypertension is a polygenic and multifactorial disease and is intimately related to salt homeostasis. Four important vasoactive peptide systems participate in regulating blood pressure and salt homeostasis. Their interplay is...
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A Case of Cerebral Salt Wasting Syndrome in Neuromyelitis Optica Spectrum Disorder

Paek YM, Lee JJ, Song P, Park HK, Cho JY

Neuromyelitis optica spectrum disorder (NMOSD) may present with area postrema syndrome, which is characterized by intractable vomiting and hiccups. Hyponatremia is common in NMOSD and is mostly associated with the...
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A Case of Cerebral Salt Wasting Syndrome associated with Tuberculous Meningitis

Rho SH, Choi JY, Nam TM, Kim HK, Lee SJ, Jeong IK, Hong EG, Choi CS, Kim DM, Yu JM, Ihm SH, Choi MG, Yoo HJ, Park SW, Kim HC

  • KMID: 2200051
  • J Korean Soc Endocrinol.
  • 2002 Oct;17(5):698-704.
Hyponatremia in patients with central nervous system disorders is suggestive of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), and volume restriction is recommended for its correction. However, if...
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A Case of Cerebral Salt Wasting Syndrome after Surgical Excision of a Giant Acoustic Neuroma

Koo YC, Hwang CS, Koh SH, Lee WS

Cerebral Salt Wasting Syndrome (CSWS) is defined as the development of extracellular volume depletion due to a dysfunction of the renal sodium transport system. Differentiation of CSWS from the Symdrome...
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Hyponatremia in Patients with Subarachnoid Hemorrhage (A Study of Blood Volume)

Park SH, Myung HJ

  • KMID: 1662041
  • J Korean Neurol Assoc.
  • 1986 Jun;4(1):78-85.
This study was performed to account for the hyponatremic phenomenon in patients with subarachnoid hemorrhage (SAH) and to discuss the concept of SIADH which has been disputed as a responsible...
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Renal functional responses to a centrally-administered 5-HT-1A agonist in the anesthetized rabbits

Lim YC, Kim KS, Kook YJ, Koh JT

  • KMID: 2285175
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):315-323.
Central tryptaminergic system has been shown to play an important role in the regulation of renal function: 5-HT-1 (5-hydroxytryptamine-1) receptors might seem to mediate the diuresis and natriuresis, whereas the 5-HT-2 and 5-HT-3...
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Amiloride Action on Oxamide Treated Kidneys and lnfluence of Oxamide on the Distribution of lntrarenal Blood Flow

Cho KS, Min BK, Choi BK, Kook YJ

  • KMID: 1678171
  • Korean J Urol.
  • 1980 Feb;21(1):8-17.
In an attempt to obtain evidence in the mechanism of stone formation, the effectiveness of Amiloride. a K-sparing diuretic known to act on the distal nephron. on the kidney with...
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The Potential Cardioprotective Mechanism of Sodium-Glucose Cotransporter 2 Inhibitors

Jeon JH

The potential mechanism by which sodium-glucose cotransporter 2 (SGLT2) inhibitors prevent cardiovascular disease (CVD) is being widely investigated. Improved insulin resistance, along with decreased body fat mass associated with SGLT2...
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Renal sodium handling and sodium sensitivity

Frame AA, Wainford R

The pathophysiology of hypertension, which affects over 1 billion individuals worldwide, involves the integration of the actions of multiple organ systems, including the kidney. The kidney, which governs sodium excretion...
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Adrenomedullin and The Kidney

Kim W

  • KMID: 2134793
  • Electrolyte Blood Press.
  • 2005 Mar;3(1):24-31.
Adrenomedullin (AM) is a multi-functional peptide discovered in human pheochromocytoma. Initially, it was suggested that AM was synthesized only by tumor cells, however, subsequent studies revealed that it was produced...
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A Case of Cerebral Salt Wasting Syndrome Associated with Tuberculous Meningitis

Lee JY, Lee ES, Lee JH, Lim EJ, Kim HS, Jang JS, Kim HK, Kim DM, Park YB, Lee JY, Mo EK

  • KMID: 2318668
  • Tuberc Respir Dis.
  • 2005 Sep;59(3):306-310.
Hyponatremia which is due to excessive sodium loss in the urine and decrease in extracellular fluid volume following an acute or chronic central nervous system injury, has been conjunctively described...
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Cerebral salt-wasting syndrome after hematopoietic stem cell transplantation in adolescents: 3 case reports

Jeon YJ, Lee HY, Jung IA, Cho WK, Cho B, Suh BK

Cerebral salt-wasting syndrome (CSWS) is a rare disease characterized by a extracellular volume depletion and hyponatremia induced by marked natriuresis. It is mainly reported in patients who experience a central...
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Cerebral salt wasting following pituitary surgery for macroadenoma

Song TH, La SS, Bang CS, Lee SS, Kang HY, Kim HJ, Lee SK

  • KMID: 2257832
  • Korean J Med.
  • 2007 Oct;73(4):432-437.
The central nervous system (CNS) has important roles in the regulation of sodium and water homeostasis, so the risk of hyponatremia is increased for patients with neurological disorders. Cerebral salt...
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