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Comparison of Collecting Methods of Nasal Fluids Using Albumin after Nasal Provocation in Allergic Patients

Kim YH, Jang TY, Kim JE, Lim DW, Kim KS

BACKGROUND AND OBJECTIVES: Although different methods of collecting nasal fluid exist and can influence the result of the study, there have not been any studies made yet to compare the...
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Detection of Staphylococcus Aureus Exotoxins(SEA, TSST-1) in Nasal Polyp with Chronic Rhinosinusitis Patients

Ha J, Gang I, Kim ST

BACKGROUND AND OBJECTIVES: Staphylococcus aureus (S. aureus) exotoxins have been implicated in the pathogenesis of chronic sinusitis with nasal polyp. The aim of this study was to identify the interplay...
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The Usefulness as a Specific Marker of Blood and Nasal Lavage Fluid YKL-40 in Allergic Rhinitis Patients

Park DS, Lee YJ, Lim J, Yoo SW, Nam GS, Lee JH

BACKGROUND AND OBJECTIVES: Chitin is a recognition element for tissue infiltration by innate cells implicated in allergy and asthma. Chitinases are characterized by the ability to cleave chitin. YKL-40, the...
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Atomized Nasal Douche: Our Experience

Passali D, Mezzedimi , Passali GC, Passali FM, Bellussi L

  • KMID: 2297708
  • J Rhinol.
  • 2001 May;8(1, 2):50-53.
BACKGROUND AND OBJECTIVES: A recently proposed apparatus for the treatment of nasal inflammatory affections is the atomized nasal douche. The aim of the paper was to assess the efficacy of...
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Increased vascular permeability and reduced neutral endopeptidase activity in rat nasal mucosa after ozone exposure

Kim YM, Jung BJ, Kim BK, Rha KS

  • KMID: 2275671
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):611-615.
BACKGROUND AND OBJECTIVES: Exposure to ozone has several effects on the respiratory tract, including airway inflammation and hyperresponsiveness. It has been suggested that these were associated with decreased NEP...
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The Comparative Study of Mucociliary Clearance with Long-term Hypertonic Saline versus Normal Saline Nasal Wash of Normal Person and Patients after Endoscopic Sinus Surgery

Roh HJ, Youn SH, Kwak DH, Lee GS, Moon HS, Kim SW, Lee JD

  • KMID: 1874418
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Oct;43(10):1067-1072.
BACKGROUND AND OBJECTIVES: Nasal irrigation, a conventional therapy for both surgical and nonsurgical patients with a history of chronic rhinosinusitis, aids in the clearance of secretions, debris, and intranasal crusts....
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Effects of Nasal Instillation of Staphylococcal Enterotoxin B on Nasal and Bronchial Mucosa in BALB/c Mouse

Jin SY, Kim EH, Lee GH, Park YK, Kim YM, Rha KS

  • KMID: 2297606
  • J Rhinol.
  • 2011 May;18(1):35-42.
BACKGROUND AND OBJECTIVES: The effect of nasal exposure to staphylococcal enterotoxin in the pathogenesis of allergic rhinitis remains controversial. We sought to determine the effect of increasing doses of intranasally...
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Effects of Corticosteroid on Expression of IL-18 in the Airway Mucosa of Allergic Rhinitis Mouse Model

Kim SW, Jeon YK, Hong SC, Won TB, Kim YM, Rhee CS, Min YG

  • KMID: 2131883
  • J Rhinol.
  • 2006 Nov;13(2):101-106.
Background: This study aimed to investigate the release and response of IL-18 to steroid treatment in the allergic rhinitis (AR) mouse model. MATERIALS AND METHODS: BALB/c mice were sensitized systematically...
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A comparison of the efficacy of amoxicillin and nasal irrigation in treatment of acute sinusitis in children

Khoshdel A, Panahande , Noorbakhsh MK, Malek Ahmadi MR, Lotfizadeh M, Parvin N

PURPOSE: The efficacy of antibiotic therapy for acute sinusitis is controversial. This study aimed to compare the efficacies of amoxicillin with nasal irrigation and nasal irrigation alone for acute sinusitis...
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Recent update of local allergic rhinitis

Cho SH

Rhinitis is a common airway disease that can affect patient's quality of life and social activities. Rhinitis comprises heterogenous diseases and classified as allergic rhinitis (AR) or nonallergic rhinitis (NAR)...
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Effect of Long-Term Low-Dose Macrolide Therapy in Children with Chronic Rhinosinusitis

Kim ST, Lee JH, Cha HE, Choi JH, Hwang YJ, Chun YS

  • KMID: 2223297
  • J Rhinol.
  • 2003 Nov;10(1, 2):14-18.
Backgrounds and Objectives: We studied the effect of long-term low-dose macrolide therapy on the level of IL-8, IL-1 beta, and TNF-alpha in the nasal secretions get from children with chronic...
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Medical Management of Chronic Rhinosinusitis

Kim ST

There is no universally accepted regimen for the treatment of chronic rhinosinusitis (CRS). However, the maximal medical treatment has shown that it can reduce the surgical treatment rate for CRS....
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The Effectiveness of Budesonide Nasal Irrigation After Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Asthma

Kang TW, Chung JH, Cho SH, Lee SH, Kim KR, Jeong JH

OBJECTIVES: Budesonide nasal irrigation was introduced recently for postoperative management of patients with chronic rhinosinusitis. The safety and therapeutic effectiveness of this procedure is becoming accepted by many physicians. The...
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Anti-Allergic Effects of Aloe Glycoprotein (NY945) on Ovalbumin-Induced Airway Allergy in the Guinea Pig

Yun JB, Seong WJ, Chung MH, Min YG

  • KMID: 2131795
  • J Rhinol.
  • 2002 Nov;9(1, 2):16-23.
BACKGROUND AND OBJECTIVES: Aloe is one of the well known substances to decrease inflammation and promote wound healing. Although little is known about its mechanism, recent studies suggest that aloe...
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The Effects of Hypertonic Saline Irrigation on Nasal Mucus Secretion in Patient with Chronic Rhinosinusitis

Kim JS, Choi YJ, Sohn JH, Lee CM, Lee YJ, Jang HU

  • KMID: 1875139
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Sep;48(9):1122-1125.
BACKGROUND AND OBJECTIVES: Various saline solution formulae for nasal irrigation have been used frequently in patients with rhinosinusitis. However, there are not enough scientific evidences supporting the effect of irrigation...
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A Prospective Randomized Open Trial of Nasal Irrigation and Nasal Decongestant for Sinusitis in Children

Cho YS, Kim MS, Chun YH, Yoon JS, Kim HH, Kim JT, Lee JS

  • KMID: 2315032
  • Pediatr Allergy Respir Dis.
  • 2010 Dec;20(4):232-237.
PURPOSE: The management of sinusitis in children is controversial. Antibiotic is known as the most essential management. Despite nasal irrigation and nasal decongestant have been used as adjunctive treatments of...
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An Intratracheal Challenge Murine Model of Asthma: Can Bronchial Inflammation Affect the Nose?

Xie J, Xi Y, Zhang Q, Chen G, Wei L, Lai K, Zhong N

PURPOSE: Extensive data support the influence of the upper airway on lower airway inflammation and pathophysiology in allergic disease. However, few studies have focused on allergic inflammation in the nose...
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Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Jiao J, Zhang L

The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can...
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Eosinophil-derived neurotoxin: a novel biomarker for diagnosis and monitoring of asthma

Kim CK

Asthma is associated with increased levels of eosinophils in tissues, body fluids, and bone marrow. Elevated levels of eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) have been noted in...
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Effectiveness of Washing Nasolacrimal Duct as an Additional Therapy after Dacryocystorhinostomy

Ha TS, Na KS, Chi NC

  • KMID: 2124604
  • J Korean Ophthalmol Soc.
  • 2000 Nov;41(11):2308-2312.
The surgical methods for the obstruction of nasolacrimal duct include conventional dacryocystorhinostomy and nasal endoscopic dacryocystorhinostomy.The authors followed 52 eyes of 54 patients who had undergone conventional or endoscopic dacryocystorhinostomy...
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