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Cognitive improvement effect of gintonin might be associated with blood-brain barrier permeability enhancement: dynamic contrastenhanced MRI pilot study

Lee WJ, Shin YW, Chang H, Shin HR, Kim WW, Jung SW, Choi SH, Kim M, Nah SY

Along with the multiple neuroprotective effect, recent studies suggest that gintonin might increase the blood brain barrier permeability. We evaluated the effect of gintonin on the vascular permeability changes in...
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Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing

Kim HJ, Kim JY, Lee BH, Choi SH, Rhim H, Kim HC, Ahn SY, Jeong SW, Jang M, Cho IH, Nah SY

Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate...
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Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents

Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY

Quercetin is a flavonoid usually found in fruits and vegetables. Aside from its antioxidative effects, quercetin, like other flavonoids, has a various neuropharmacological actions. Quercetin-3-O-rhamnoside (Rham1), quercetin-3-O-rutinoside (Rutin), and quercetin-3-(2(G)-rhamnosylrutinoside...
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Mesocolon Laceration Following Colonoscopy

Choi YJ, Park JS, Kim GE, Han JY, Nah SY, Bang BW

Colonoscopic examination is a safe procedure, however, unexpected complications can sometimes occur. Bleeding and perforation of the colon have been reported as the most common complications. Hemoperitoneum after colonoscopy is...
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Therapeutic Drug Concentrations of Teicoplanin in Clinical Settings

Nah SY, Im JH, Yeo JY, Baek JH, Kim CW, Nam MS, Lee HK, Chung MH, Lee JS

BACKGROUND: Teicoplanin is a glycopeptide antibiotic that is widely used in clinical practice for the treatment of infections caused by drug-resistant Gram-positive bacteria. The aim of this study was to...
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Activation of Lysophosphatidic Acid Receptor Is Coupled to Enhancement of Ca(2+)-Activated Potassium Channel Currents

Choi SH, Lee BH, Kim HJ, Hwang SH, Lee SM, Nah SY

The calcium-activated K+ (BKCa) channel is one of the potassium-selective ion channels that are present in the nervous and vascular systems. Ca2+ is the main regulator of BKCa channel activation....
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Resveratrol Inhibits GABAC rho Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Choi SH, Hwang SH, Kim HJ, Lee JH, Nah SY

Resveratrol is a phytoalexin found in grapes, red wine, and berries. Resveratrol has been known to have many beneficial health effects, such as anti-cancer, neuroprotective, anti-inflammatory, and life-prolonging effects. However,...
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Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents

Lee BH, Hwang SH, Choi SH, Kim HJ, Lee JH, Lee SM, Ahn YG, Nah SY

Ginsenosides, one of the active ingredients of Panax ginseng, show various pharmacological and physiological effects, and they are converted into compound K (CK) or protopanaxatriol (M4) by intestinal microorganisms. CK...
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Carriage Rates and Serogroups of Neisseria meningitidis among Freshmen in a University Dormitory in Korea

Durey A, Bae SM, Lee HJ, Nah SY, Kim M, Baek JH, Kang YH, Chung MH, Lee JS

PURPOSE: Neisseria meningitidis is a leading cause of bacterial meningitis in young adults. University students, especially those living in dormitories, have been known to be at increased risk of meningococcal...
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Effects of Protopanaxatriol-Ginsenoside Metabolites on Rat N-Methyl-D-Aspartic Acid Receptor-Mediated Ion Currents

Shin TJ, Hwang SH, Choi SH, Lee BH, Kang J, Kim HJ, Zukin RS, Rhim H, Nah SY

Ginsenosides are low molecular weight glycosides found in ginseng that exhibit neuroprotective effects through inhibition of N-methyl-D-aspartic acid (NMDA) receptor channel activity. Ginsenosides, like other natural compounds, are metabolized by...
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Double Primary Presentation of Liposarcoma and Ewing's Sarcoma: A Case Report

Park HW, Jung ST, Nah SY

The development of different entities of soft tissue sarcoma in one patient is rare. It usually affects head and neck or abdominal region, whereas those affecting the extremities are much...
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Variations in Number of Hospitalized Patients with Cardiopulmonary Diseases Associated with 2009 H1N1 Pandemic Influenza in a Tertiary Teaching Hospital - Comparison with Seasonal Influenza

Nah SY, Hong JT, Im JH, Lee JH, Durey A, Kim M, Lee HJ, Park SK, Chung MH, Baek JH, Lee JS

BACKGROUND: The world encountered the global outbreak of an H1N1 influenza pandemic in 2009. Influenza has accounted for grave outcomes, not only through infectious complications, but also through the exacerbation...
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Inhibitory Effects of Quercetin on Muscle-type of Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Shin TJ, Hwang SH, Choi SH, Kang J, Kim HJ, Park CW, Lee SH, Nah SY

The flavonoid quercetin is a low molecular weight compound generally found in apple, gingko, tomato, onion and other red-colored fruits and vegetables. Like other flavonoids, quercetin has diverse pharmacological actions....
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Quercetin Inhibits alpha3beta4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY

  • KMID: 2389104
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):17-22.
Quercetin mainly exists in the skin of colored fruits and vegetables as one of flavonoids. Recent studies show that quercetin, like other flavonoids, has diverse pharmacological actions. However, relatively little...
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Innate Immunity and Genetic Susceptibility to Severe Respiratory Syncytial Virus Infection : Lack of an Association with Mannose Binding Lectin Gene Polymorphism

Choi EH, Kim HS, Yun BY, Choi SE, Nah SY, Kim DH, Park KW, Lee HJ

PURPOSE: We hypothesized that mannose binding lectin gene(MBL2), a key molecule of innate immunity, may contirbute to the development and the outcome of respiratory syncytial virus(RSV) disease in early childhood....
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Effects of Ginsenosides on Relaxation of Rabbit Vaginal Smooth Muscle

Park K, Kim GS, Kim SO, Kim DS, Kim MK, Park JK, Nah SY, Kim KK

  • KMID: 2298679
  • Korean J Androl.
  • 2003 Aug;21(2):98-102.
PURPOSE: Ginseng has been used throughout the Far East, including Korea and China, as a tonic and restorative agent to maintain physical vitality. The main pharmacoactive molecules of ginseng are...
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Effect of prostaglandins D2, E2 and I2 on the regulation of KATP channel activity in rat cardiac myocytes

Ju JM, Nah SY, Kim JH

  • KMID: 2071552
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):507-512.
Contribution of prostaglandins D2, E2 and I2 (PGD2, PGE2 and PGI2) on the regulation of ATP-sensitive K+ channel (KATP channel) was investigated in isolated single rat ventricular cardiac myocytes using the patch clamp...
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Epidemiology of Influenza Virus over 8 Years (1990~1998) in Seoul, Korea

Nah SY, Park SE, Park JY, Lee HJ

  • KMID: 2248232
  • Korean J Infect Dis.
  • 1999 Jun;31(3):210-216.
BACKGROUND: Influenza virus is well known to cause recurrent epidemics almost every winter. However, information regarding the epidemiologic pattern of influenza virus in Korea is limited. In this study, the...
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Epidemiologic and Clinical Features of Salmonellosis in Children over 10 Years(1986-1995)

Nah SY, Park JY, Lee HJ, Seo JK

  • KMID: 2248725
  • Korean J Infect Dis.
  • 1999 Apr;31(2):129-135.
BACKGROUND: With the improvement of sanitary conditions, epidemiologic features and relative frequency of serogroups of salmonella have changed in developed countries. Also there are increasing reports on occurrence of multidrug-resistant...
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Tuberculosis in Infants

Kim EK, Nah SY, Park JY, Choi EH, Lee HJ

PURPOSE: The risk of severe tuberculous disease such as meningitis or miliary tuberculosis increases as younger is the child at the time of infection. Therefore, the early diagnosis and prompt...
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