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White spots around colorectal tumors are cancer-related findings and may aid endoscopic diagnosis: a prospective study in Japan

Korekawa K, Shimoyama Y, Fujishima F, Nagai H, Naito T, Moroi R, Shiga H, Kakuta Y, Kinouchi Y, Masamune A

Background/Aims: During endoscopy, white spots (WS) are sometimes observed around benign or malignant colorectal tumors; however, few reports have investigated WS, and their significance remains unknown. Therefore, we investigated the...
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Live-attenuated vaccination in patients with inflammatory bowel disease while continuing or after elective switch to vedolizumab

Shiga H, Nagai H, Shimoyama Y, Naito T, Moroi R, Kakuta Y, Kinouchi Y, Masamune A

Background/Aims: Vedolizumab (VDZ) is a gut-selective agent with a favorable safety profile. We aimed to assess the feasibility of elective switch from other advanced therapies to VDZ and subsequent live-attenuated...
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Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)

Kondo T, Yoshida S, Nagai H, Takeshita , Mino M, Morioka H, Nakajima T, Kusakabe K, Okada T

In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet...
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