- Experimental meningoencephalitis by Naegleria fowleri in mice
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Ahn MH, Im KI
- KMID: 1715069
- Korean J Parasitol.
- 1984 Dec;22(2):253-258.
- doi: 10.3347/kjp.1984.22.2.253
Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size... -
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- Immunodepression during experimental Naegleria meningoencephalitis in mice
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Im KI, Ryu JS, Lee KT
- KMID: 1714972
- Korean J Parasitol.
- 1987 Dec;25(2):195-198.
- doi: 10.3347/kjp.1987.25.2.195
In order to test the function of lymphocytes in Naegleria fowleri-infected mice, the in vitro blastogenic response of splenocyte cultures to non-specific mitogens was studied. Concanavalin A and lipopolysaccharide stimulation... -
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- Failure of immunization with Naegleria fowleri in mice born to immune mothers
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Im KI, Lee KT
- KMID: 1715170
- Korean J Parasitol.
- 1985 Jun;23(1):151-155.
- doi: 10.3347/kjp.1985.23.1.151
Female BALB/c mice weighing 18-20 g were immunized by three injections of 1 x 10(6) Naegleria fowleri trophozoites intraperitoneally at the interval of one week 6 times for the pregnant... -
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- Protective immunity against Naegleria meningoencephalitis in mice
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Lee SG, Im KI, Lee KT
- KMID: 1715147
- Korean J Parasitol.
- 1985 Dec;23(2):293-299.
- doi: 10.3347/kjp.1985.23.2.293
This study is to verify the protective ability against experimental Naegleria meningoencephalitis by immunization with Naegleria fowleri in mice. Naegleria fowleri, strain 0359, and Naegleria gruberi, strain EGB, were used... -
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- The nfa1 Gene Contributed on the Contact-dependent Pathogenic Mechanisms of Naegleria fowleri
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Shin HJ
- KMID: 1460255
- Hanyang Med Rev.
- 2010 Aug;30(3):204-212.
- doi: 10.7599/hmr.2010.30.3.204
Free-living Naegleria fowleri is a causal agent of primary amoebic meningoencephalitis in mainly children and young adults. An nfa1 gene, encoding 360 bp of nucleotides, was cloned from a N.... -
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- Contact-Independent Cell Death of Human Microglial Cells due to Pathogenic Naegleria fowleri Trophozoites
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Kim JH, Kim D, Shin HJ
- KMID: 1720586
- Korean J Parasitol.
- 2008 Dec;46(4):217-221.
- doi: 10.3347/kjp.2008.46.4.217
Free-living Naegleria fowleri leads to a fatal infection known as primary amebic meningoencephalitis in humans. Previously, the target cell death could be induced by phagocytic activity of N. fowleri as... -
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- Immunological tests by anti-free-living amoebas serum produced in experimental animals I. Immobilization of free-living amoebas in vitro by rabbit antiserum
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Im KI, Oh HS
- KMID: 1713277
- Korean J Parasitol.
- 1978 Jun;16(1):41-46.
- doi: 10.3347/kjp.1978.16.1.41
Rabbits were immunized with free-living amoebas by intravenous injections. The amoebas were Acanthamoeba culbertsoni and Naegleria fowleri and obtained by axenic cultivation in CGVS medium. Each rabbit received 10(6) of... -
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- Immunological tests by anti-free-living amoebas serum produced in experimental animals II. Indirect fluorescent antibody titer of anti-free-living amoebas serum produced in rabbits
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Im KI, Soh CT
- KMID: 1384358
- Korean J Parasitol.
- 1978 Dec;16(2):134-139.
- doi: 10.3347/kjp.1978.16.2.134
The indirect fluorescent antibody test was performed to demonstrate the antibody production in the rabbits immunized with free-living amoebas; Acanthamoeba culbertsoni and Naegleria fowleri, and antibody titer changes by immunization... -
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- Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri
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Jeong SR, Kang SY, Lee SC, Song KJ, Im KI, Shin HJ
- KMID: 1720481
- Korean J Parasitol.
- 2004 Mar;42(1):35-40.
- doi: 10.3347/kjp.2004.42.1.35
The nfa1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed... -
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- Blastogenic responses of splenic lymphocytes to Naegleria fowleri lysates and T-cell mitogen in mice with primary amoebic meningoencephalitis
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Park KM, Ryu JS, Im KI
- KMID: 1714976
- Korean J Parasitol.
- 1987 Jun;25(1):1-6.
- doi: 10.3347/kjp.1987.25.1.1
This study was to observe the changes of blastogenic responses of splenic lymphocytes to T-cell mitogens, N. fowleri lysate and concanavalin A, and serum antibody titer during the course of... -
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- Passive immunity by splenocyte transfer against amebic meningoencephalitis in mice
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Im KI, Ryu JS
- KMID: 1714932
- Korean J Parasitol.
- 1988 Sep;26(3):169-173.
- doi: 10.3347/kjp.1988.26.3.169
The role of passive cell-mediated transfer of immunity against primary amoebic meningoencephalitis(PAME) in mice was studied. Naegleria fowleri, ITMAP 359, were cultured in CGVS medium. The ICR mice used were... -
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- Naegleria fowleri Lysate Induces Strong Cytopathic Effects and Pro-inflammatory Cytokine Release in Rat Microglial Cells
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Lee YJ, Park CE, Kim JH, Sohn HJ, Lee J, Jung SY, Shin HJ
- KMID: 1715653
- Korean J Parasitol.
- 2011 Sep;49(3):285-290.
- doi: 10.3347/kjp.2011.49.3.285
Naegleria fowleri, a ubiquitous free-living ameba, causes fatal primary amebic meningoencephalitis in humans. N. fowleri trophozoites are known to induce cytopathic changes upon contact with microglial cells, including necrotic and... -
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- Ultrastructural observation of Naegleria fowleri trophozoite in mouse brain and axenic culture
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Ryu JS, Soh CT, Im KI
- KMID: 1715070
- Korean J Parasitol.
- 1984 Dec;22(2):259-266.
- doi: 10.3347/kjp.1984.22.2.259
Present study was undertaken to elucidate the changes of the ultrastructure of Naegleria fowleri trophozoite in brain tissue of mice and culture medium. Naegleria fowleri, 0359 strain, which used in... -
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- Changes in the pathogenicity of Naegleria fowleri by several brain passage in mice
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Lee DK, Lee KT, Im KI
- KMID: 1720253
- Korean J Parasitol.
- 1983 Dec;21(2):234-240.
- doi: 10.3347/kjp.1983.21.2.234
The pathogenicity of free-living amoeba, Naegleria fowleri, is influenced according to the strain, cultural condition and host (Culbertson et al., 1968; Carter, 1970; Wong et al., 1975). Phillips (1973) demonstrated... -
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- A Fatal Case of Naegleria fowleri Meningoencephalitis in Taiwan
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Su MY, Lee MS, Shyu LY, Lin WC, Hsiao PC, Wang CP, Ji DD, Chen KM, Lai SC
- KMID: 1499699
- Korean J Parasitol.
- 2013 Apr;51(2):203-206.
- doi: 10.3347/kjp.2013.51.2.203
After bathing at a hot spring resort, a 75-year-old man presented to the emergency department because of seizure-like attack with loss of conscious. This is the first case of primary... -
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- Immunization effect on Naegleria fowleri infection in splenectomized mice
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Han KH, Ahn MH, Min DY
- KMID: 1714955
- Korean J Parasitol.
- 1988 Mar;26(1):39-44.
- doi: 10.3347/kjp.1988.26.1.39
A pathogenic free-living amoeba, Naegleria fowleri, is a causative protozoan parasite of primary amebic meningoencephalitis in human and experimental animals. It is known that humoral and cellular immunity contribute as... -
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- Efficient Liquid Media for Encystation of Pathogenic Free-Living Amoebae
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Sohn HJ, Kang H, Seo GE, Kim JH, Jung SY, Shin HJ
- KMID: 2387178
- Korean J Parasitol.
- 2017 Jun;55(3):233-238.
- doi: 10.3347/kjp.2017.55.3.233
Pathogenic Naegleria fowleri, Acanthamoeba castellanii, and Acanthamoeba polyphaga, are distributed worldwide. They are causative agents of primary amoebic meningoencephalitis or acanthamoebic keratitis in humans, respectively. Trophozoites encyst in unfavorable environments,... -
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- Parasitic amebae in Korea
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Soh CT
- KMID: 1384441
- Korean J Parasitol.
- 1981 Feb;19(Suppl):5-93.
- doi: 10.3347/kjp.1981.19.Suppl.5
This review dealt with biology, host-parasite relationship, symptomatology, epidemiology, diagnosis, treatment of Entamoeba histolytica infection and free livng amoeba. -
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- Primary Amebic Meningoencephalitis: A Case Report
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Chen M, Ruan W, Zhang L, Hu B, Yang X
- KMID: 2453318
- Korean J Parasitol.
- 2019 Jun;57(3):291-294.
- doi: 10.3347/kjp.2019.57.3.291
Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowleri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old... -
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- Effect of splenectomy on development of primary amoebic meningoencephalitis
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Shin HJ, Im KI, Choe RS
- KMID: 1715171
- Korean J Parasitol.
- 1985 Jun;23(1):156-164.
- doi: 10.3347/kjp.1985.23.1.156
To elucidate the effect of splenectomy on the development of experimental primary amoebic meningoencephalitis in mice, the death rate and survival time of mice infected intranasally with Naegleria fowleri trophozoites... -
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