- Immunodepression during experimental Naegleria meningoencephalitis in mice
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Im KI, Ryu JS, Lee KT
- KMID: 1714972
- Korean J Parasitol.
- 1987 Dec;25(2):195-198.
- doi: 10.3347/kjp.1987.25.2.195
In order to test the function of lymphocytes in Naegleria fowleri-infected mice, the in vitro blastogenic response of splenocyte cultures to non-specific mitogens was studied. Concanavalin A and lipopolysaccharide stimulation... -
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- Experimental meningoencephalitis by Naegleria fowleri in mice
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Ahn MH, Im KI
- KMID: 1715069
- Korean J Parasitol.
- 1984 Dec;22(2):253-258.
- doi: 10.3347/kjp.1984.22.2.253
Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size... -
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- Protective immunity against Naegleria meningoencephalitis in mice
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Lee SG, Im KI, Lee KT
- KMID: 1715147
- Korean J Parasitol.
- 1985 Dec;23(2):293-299.
- doi: 10.3347/kjp.1985.23.2.293
This study is to verify the protective ability against experimental Naegleria meningoencephalitis by immunization with Naegleria fowleri in mice. Naegleria fowleri, strain 0359, and Naegleria gruberi, strain EGB, were used... -
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- Parasitic amebae in Korea
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Soh CT
- KMID: 1384441
- Korean J Parasitol.
- 1981 Feb;19(Suppl):5-93.
- doi: 10.3347/kjp.1981.19.Suppl.5
This review dealt with biology, host-parasite relationship, symptomatology, epidemiology, diagnosis, treatment of Entamoeba histolytica infection and free livng amoeba. -
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- Immunological tests by anti-free-living amoebas serum produced in experimental animals II. Indirect fluorescent antibody titer of anti-free-living amoebas serum produced in rabbits
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Im KI, Soh CT
- KMID: 1384358
- Korean J Parasitol.
- 1978 Dec;16(2):134-139.
- doi: 10.3347/kjp.1978.16.2.134
The indirect fluorescent antibody test was performed to demonstrate the antibody production in the rabbits immunized with free-living amoebas; Acanthamoeba culbertsoni and Naegleria fowleri, and antibody titer changes by immunization... -
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- Immunological tests by anti-free-living amoebas serum produced in experimental animals I. Immobilization of free-living amoebas in vitro by rabbit antiserum
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Im KI, Oh HS
- KMID: 1713277
- Korean J Parasitol.
- 1978 Jun;16(1):41-46.
- doi: 10.3347/kjp.1978.16.1.41
Rabbits were immunized with free-living amoebas by intravenous injections. The amoebas were Acanthamoeba culbertsoni and Naegleria fowleri and obtained by axenic cultivation in CGVS medium. Each rabbit received 10(6) of... -
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- Pathogenic free-living amoebae
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Im KI
- KMID: 1729477
- Korean J Parasitol.
- 1990 Dec;28(Suppl):29-39.
- doi: 10.3347/kjp.1990.28.Suppl.29
Studies on pathogenic free-living amoebae performed in Korea were briefly reviewed. One strain of Naegleria fowleri was isolated from the sewage, and 3 strains of Acanthamoeba culbertsoni from a reservoir... -
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- Failure of immunization with Naegleria fowleri in mice born to immune mothers
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Im KI, Lee KT
- KMID: 1715170
- Korean J Parasitol.
- 1985 Jun;23(1):151-155.
- doi: 10.3347/kjp.1985.23.1.151
Female BALB/c mice weighing 18-20 g were immunized by three injections of 1 x 10(6) Naegleria fowleri trophozoites intraperitoneally at the interval of one week 6 times for the pregnant... -
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- The nfa1 Gene Contributed on the Contact-dependent Pathogenic Mechanisms of Naegleria fowleri
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Shin HJ
- KMID: 1460255
- Hanyang Med Rev.
- 2010 Aug;30(3):204-212.
- doi: 10.7599/hmr.2010.30.3.204
Free-living Naegleria fowleri is a causal agent of primary amoebic meningoencephalitis in mainly children and young adults. An nfa1 gene, encoding 360 bp of nucleotides, was cloned from a N.... -
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- Ultrastructural observation of Naegleria fowleri trophozoite in mouse brain and axenic culture
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Ryu JS, Soh CT, Im KI
- KMID: 1715070
- Korean J Parasitol.
- 1984 Dec;22(2):259-266.
- doi: 10.3347/kjp.1984.22.2.259
Present study was undertaken to elucidate the changes of the ultrastructure of Naegleria fowleri trophozoite in brain tissue of mice and culture medium. Naegleria fowleri, 0359 strain, which used in... -
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- Natural killer cell activity in Naegleria fowleri infected mice
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Lee KR, Shin CO, Im K
- KMID: 1715552
- Korean J Parasitol.
- 1991 Sep;29(3):267-277.
- doi: 10.3347/kjp.1991.29.3.267
The natural killer (NK) cell activity of splenocytes and recycling capacity of NK cells were observed by combining the 51Cr-release cytotoxicity assay and single cell cytotoxicity assay against YAC-1. The... -
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- Contact-Independent Cell Death of Human Microglial Cells due to Pathogenic Naegleria fowleri Trophozoites
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Kim JH, Kim D, Shin HJ
- KMID: 1720586
- Korean J Parasitol.
- 2008 Dec;46(4):217-221.
- doi: 10.3347/kjp.2008.46.4.217
Free-living Naegleria fowleri leads to a fatal infection known as primary amebic meningoencephalitis in humans. Previously, the target cell death could be induced by phagocytic activity of N. fowleri as... -
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- The production and characterization of anti-Naegleria fowleri monoclonal antibodies
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Ryu JS, Im KI
- KMID: 1715531
- Korean J Parasitol.
- 1992 Mar;30(1):33-41.
- doi: 10.3347/kjp.1992.30.1.33
Naegleria fowleri, a free-living amoeba commonly found in moist soil and fresh water, enters the body via the nasal mucosa and migrates along the olfactory nerve to the brain, where... -
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- A Fatal Case of Naegleria fowleri Meningoencephalitis in Taiwan
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Su MY, Lee MS, Shyu LY, Lin WC, Hsiao PC, Wang CP, Ji DD, Chen KM, Lai SC
- KMID: 1499699
- Korean J Parasitol.
- 2013 Apr;51(2):203-206.
- doi: 10.3347/kjp.2013.51.2.203
After bathing at a hot spring resort, a 75-year-old man presented to the emergency department because of seizure-like attack with loss of conscious. This is the first case of primary... -
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- Immunization effect on Naegleria fowleri infection in splenectomized mice
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Han KH, Ahn MH, Min DY
- KMID: 1714955
- Korean J Parasitol.
- 1988 Mar;26(1):39-44.
- doi: 10.3347/kjp.1988.26.1.39
A pathogenic free-living amoeba, Naegleria fowleri, is a causative protozoan parasite of primary amebic meningoencephalitis in human and experimental animals. It is known that humoral and cellular immunity contribute as... -
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- Studies on the cell-mediated immunity in experimental Naegleria spp. infections
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Lee SG, Shin HJ, Im KI
- KMID: 1720280
- Korean J Parasitol.
- 1989 Sep;27(3):177-186.
- doi: 10.3347/kjp.1989.27.3.177
Observations were made on the differences in cell-mediated immune responses in the mice infected with strongly pathogenic Naegleria fowleri ITMAP 359, weakly pathogenic Naegleria jadini 0400, or non-pathogenic Naegleria gruberi... -
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- Naegleria fowleri Lysate Induces Strong Cytopathic Effects and Pro-inflammatory Cytokine Release in Rat Microglial Cells
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Lee YJ, Park CE, Kim JH, Sohn HJ, Lee J, Jung SY, Shin HJ
- KMID: 1715653
- Korean J Parasitol.
- 2011 Sep;49(3):285-290.
- doi: 10.3347/kjp.2011.49.3.285
Naegleria fowleri, a ubiquitous free-living ameba, causes fatal primary amebic meningoencephalitis in humans. N. fowleri trophozoites are known to induce cytopathic changes upon contact with microglial cells, including necrotic and... -
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- Interleukin-2 production and alteration of T cell subsets in mice infected with Naegleria fowleri
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Lyu CJ, Shin CO, Im K
- KMID: 1715469
- Korean J Parasitol.
- 1993 Sep;31(3):249-257.
- doi: 10.3347/kjp.1993.31.3.249
Naegleria fowleri is the cause of primary amoebic meningoencephalitis in man. IL-2 levels after stimulation of T lymphocytes by PHA or N. fowleri lysates, the amounts of T lymphocyte... -
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- Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri
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Jeong SR, Kang SY, Lee SC, Song KJ, Im KI, Shin HJ
- KMID: 1720481
- Korean J Parasitol.
- 2004 Mar;42(1):35-40.
- doi: 10.3347/kjp.2004.42.1.35
The nfa1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed... -
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- Primary Amebic Meningoencephalitis: A Case Report
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Chen M, Ruan W, Zhang L, Hu B, Yang X
- KMID: 2453318
- Korean J Parasitol.
- 2019 Jun;57(3):291-294.
- doi: 10.3347/kjp.2019.57.3.291
Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowleri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old... -
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