- Inhibition of rac1 Reduces PDGF-induced Reactive Oxygen Species and Proliferation in Vascular Smooth Muscle Cells
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Kong G, Lee S, Kim KS
- KMID: 648350
- J Korean Med Sci.
- 2001 Dec;16(6):712-718.
- doi: 10.3346/jkms.2001.16.6.712
In vascular smooth muscle cells, reactive oxygen species (ROS) were known to mediate platelet-derived growth factor (PDGF)-induced cell proliferation and NADH/NADPH oxidase is the major source of ROS. NADH/NADPH oxidase... -
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- Up-regulation of BLT2 is critical for the survival of bladder cancer cells
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Seo JM, Cho KJ, Kim EY, Choi MH, Chung BC, Kim JH
- KMID: 1109401
- Exp Mol Med.
- 2011 Mar;43(3):129-137.
- doi: 10.3858/emm.2011.43.3.014
The incidence rates of urinary bladder cancer continue to rise yearly, and thus new therapeutic approaches and early diagnostic markers for bladder cancer are urgently needed. Thus, identifying the key... -
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- Expression of NAD(P)H Oxidase Subunits and Their Contribution to Cardiovascular Damage in Aldosterone/Salt-Induced Hypertensive Rat
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Park YM, Lim BH, Touyz RM, Park JB
- KMID: 1107531
- J Korean Med Sci.
- 2008 Dec;23(6):1039-1045.
- doi: 10.3346/jkms.2008.23.6.1039
NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this... -
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- Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content
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Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069806
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S146-S154.
- doi: 10.3346/jkms.2014.29.S2.S146
The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which... -
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