- Ionic Mechanisms of Desflurane on Prolongation of Action Potential Duration in Rat Ventricular Myocytes
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Chae JE, Kim HS, Ahn DS, Park WK
- KMID: 1779708
- Yonsei Med J.
- 2012 Jan;53(1):204-212.
- doi: 10.3349/ymj.2012.53.1.204
PURPOSE: Despite the fact that desflurane prolongs the QTC interval in humans, little is known about the mechanisms that underlie these actions. We investigated the effects of desflurane on action... -
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- Effects of Mixed Herbal Extracts from Parched Puerariae Radix, Gingered Magnoliae Cortex, Glycyrrhizae Radix and Euphorbiae Radix (KIOM-79) on Cardiac Ion Channels and Action Potentials
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Park SJ, Choi KS, Shin DH, Kim JS, Jang DS, Youm JB, Choe H, Earm YE, Kim SJ
- KMID: 1779155
- J Korean Med Sci.
- 2009 Jun;24(3):403-412.
- doi: 10.3346/jkms.2009.24.3.403
KIOM-79, a mixture of ethanol extracts from four herbs (parched Puerariae radix, gingered Magnoliae cortex, Glycyrrhizae radix and Euphorbiae radix), has been developed for the potential therapeutic application to diabetic... -
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- Aldosterone Upregulates Connective Tissue Growth Factor Gene Expression via p38 MAPK Pathway and Mineralocorticoid Receptor in Ventricular Myocytes
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Lee YS, Kim JA, Kim KL, Jang HS, Kim JM, Lee JY, Shin IS, Lee JS, Suh W, Choi JH, Jeon ES, Byun J, Kim DK
- KMID: 1778560
- J Korean Med Sci.
- 2004 Dec;19(6):805-811.
- doi: 10.3346/jkms.2004.19.6.805
The effect of aldosterone on connective tissue growth factor (CTGF) was examined in rat embryonic ventricular myocytes. Upon aldosterone treatment, CTGF expression was significantly increased in a dose and time-dependent... -
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- Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+increase are reciprocally modulated in rat cardiomyocytes
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Kim SY, Kim SJ, Kim BJ, Rah SY, Chung SM, Im MJ, Kim UH
- KMID: 1098088
- Exp Mol Med.
- 2006 Oct;38(5):535-545.
Doxorubicin (DOX) is one of the most potent anticancer drugs and induces acute cardiac arrhythmias and chronic cumulative cardiomyopathy. Though DOX-induced cardiotoxicity is known to be caused mainly by ROS... -
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- Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway
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Yang L, Zou X, Liang Q, Chen H, Feng J, Yan L, Wang Z, Zhou D, Li S, Yao S, Zheng Z
- KMID: 1103682
- Exp Mol Med.
- 2007 Feb;39(1):65-73.
Cardiomyocyte hypertrophy is a major cause of morbidity and mortality worldwide. The aim of this study is to determine the effects of sodium tanshinone IIA sulfonate (STS) on cardiomyocyte hypertrophy... -
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- The association of Hsp90 expression induced by aspirin with anti-stress damage in chicken myocardial cells
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Zhang XH, Zhu HS, Qian Z, Tang S, Wu D, Kemper N, Hartung J, Bao ED
- KMID: 2363333
- J Vet Sci.
- 2016 Mar;17(1):35-44.
- doi: 10.4142/jvs.2016.17.1.35
The protective effect of aspirin during exposure to heat stress in broiler chickens was investigated. We assayed pathological damage, expression and distribution of Hsp90 protein and hsp90 mRNA expression in... -
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- Cardioprotection Via Modulation of Calcium Homeostasis by Thiopental in Hypoxia-Reoxygenated Neonatal Rat Cardiomyocytes
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Kim HS, Hwang KC, Park WK
- KMID: 1126016
- Yonsei Med J.
- 2010 Mar;51(2):187-196.
- doi: 10.3349/ymj.2010.51.2.187
PURPOSE: Ca2+ homeostasis plays an important role in myocardial cell injury induced by hypoxia-reoxygenation, and prevention of intracellular Ca2+ overload is key to cardioprotection. Even though thiopental is a frequently... -
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