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Comparison of an Automated Repetitive Sequence-based PCR Microbial Typing System with IS6110-Restriction Fragment Length Polymorphism for Epidemiologic Investigation of Clinical Mycobacterium tuberculosis Isolates in Korea

Jang MH, Choi GE, Shin BM, Lee SH, Kim SR, Chang CL, Kim JM

Tuberculosis remains a severe public health problem worldwide. Presently, genotyping is used for conducting epidemiologic and clinical studies on tuberculosis cases. We evaluated the efficacy of the repetitive sequence-based PCR...
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Strain Typing of Mycobacterium tuberculosis Isolates from Korea by Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats

Yun KW, Song EJ, Choi GE, Hwang IK, Lee EY, Chang CL

BACKGROUND: Mycobacterium tuberculosis is one of the most clinically significant infectious agents. Especially during mass outbreaks, accurate identification and monitoring are required. The proportion of Beijing family members is very...
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IS6110-Restriction Fragment Length Polymorphism and Spoligotyping Analysis of Mycobacterium tuberculosis Clinical Isolates for Investigating Epidemiologic Distribution in Korea

Choi GE, Jang MH, Song EJ, Jeong SH, Kim JS, Lee WG, Uh Y, Roh KH, Lee HS, Shin JH, Ryoo NH, Kim YR, Jeong J, Kim JH, Lee SM, Yi J, Hwang SH, Kim HH, Lee EY, Chang CL, Kim MB, Kim YD

The Beijing family of Mycobacterium tuberculosis has been emerging in the world. However, there are few nationwide data of genotypic distribution in Korea. This study aimed to identify the genotypic...
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Application of Single-nucleotide Polymorphism and Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats Analyses to Clinical Mycobacterium tuberculosis Isolates from Korea

Choi GE, Jang MH, Cho HJ, Lee SM, Yi J, Lee EY, Chang CL, Kim YD, Kim MB

BACKGROUND: Single-nucleotide polymorphism (SNP) analysis is a powerful strategy for large-scale molecular population studies examining phylogenetic relationships among bacterial strains. Mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) can...
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