- A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride
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Rim KT, Kim SJ
- KMID: 2317194
- Saf Health Work.
- 2015 Sep;6(3):184-191.
- doi: 10.1016/j.shaw.2015.05.005
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.... -
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- Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats
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Yang HJ, Lee SH, Jin Y, Choi JH, Han CH, Lee MH
- KMID: 1114850
- J Vet Sci.
- 2005 Jun;6(2):103-109.
The toxicity of acrylamide was evaluated through mutagenicity of Salmonella, chromosome aberration of Chinese hamster lung fibroblasts, micronucleus formation in mice and reproductive toxicity in rats. Based on Ames test,... -
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- Physico-chemical Nature and Mutagenic Activity of Ambient Dust in Seoul
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Chung Y
- KMID: 693066
- Yonsei Med J.
- 1987 Mar;28(1):52-59.
- doi: 10.3349/ymj.1987.28.1.52
This study deals with the serious pollution of Seoul's ambient air and extends a warning regarding its adverse effects on human health. The collected dust samples exceeded the legal standard... -
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- An Experimental Study on the Chemopreventive effect of Chlorophyllin in Hamster Cheek Pouch Tumor induced by 7, 12-dimethylbenz[a]anthracene
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Yoon KH
- KMID: 1961290
- J Korean Assoc Oral Maxillofac Surg.
- 2000 Apr;26(2):137-145.
Carcinogenesis is a multi-stage process that generally consists of at least three steps; initiation, promotion, and progression. If one of these carcinogenic steps were suppressed or delayed, the cancer could... -
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- Mutagenic and Anti-Mutagenic Properties of Meju and Other Korean Food Products from Fermented Soybeans
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Rapp NS, Seong YC, Shin H, Hong LS, Jang JY, Seel DJ
- KMID: 1119199
- Yonsei Med J.
- 1988 Jun;29(2):117-123.
- doi: 10.3349/ymj.1988.29.2.117
ln order to investigate the mutagenic activity of Meju, an important component of the Korean diet, both chemical techniques and the Ames test were used. To determine if antimutagenic activity... -
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- Appropriate In Vitro Methods for Genotoxicity Testing of Silver Nanoparticles
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Kim HR, Park YJ, Shin DY, Oh SM, Chung KH
- KMID: 2380115
- Environ Health Toxicol.
- 2013 ;28(1):e2013003.
OBJECTIVES: We investigated the genotoxic effects of 40-59 nm silver nanoparticles (Ag-NPs) by bacterial reverse mutation assay (Ames test), in vitro comet assay and micronucleus (MN) assay. In particular, we... -
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- The Effects of Etodolac, Nimesulid and Naproxen Sodium on the Frequency of Sister Chromatid Exchange after Enclused Third Molars Surgery
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Koseoglu B, Ozturk S, Kocak H, Palanduz S, Cefle K
- KMID: 2158192
- Yonsei Med J.
- 2008 Oct;49(5):742-747.
- doi: 10.3349/ymj.2008.49.5.742
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used in oral surgical procedures in dentistry. The evaluation of the frequency of sister chromatid exchange (SCE) is accepted as a reliable cytogenetic... -
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- Morphological transformation induced by silver nanoparticles in a Balb/c 3T3 A31-1-1 mouse cell model to evaluate in vitro carcinogenic potential
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Choo W, Moon B, Song S, Oh SM
- KMID: 2411248
- Environ Health Toxicol.
- 2017 ;32(1):e2017016.
- doi: 10.5620/eht.e2017016
Carcinogenesis is a complex process involved in genotoxic and non-genotoxic pathways. The carcinogenic potential of silver nanoparticles (AgNPs) has been predicted by examining their genotoxic effects using several in vitro... -
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- Antimutagenic and anticarcinogenic effect of methanol extracts of Petasites japonicus Maxim leaves
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Kang HG, Jeong SH, Cho JH
- KMID: 1106157
- J Vet Sci.
- 2010 Mar;11(1):51-58.
- doi: 10.4142/jvs.2010.11.1.51
The methanol extract from the leaves of Petasites japonicus Maxim (PJ) was studied for its (anti-)mutagenic effect with the SOS chromotest and reverse mutation assay. The (anti-)carcinogenic effects were evaluated... -
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- In vivo Genotoxicity of Silver Nanoparticles after 90-day Silver Nanoparticle Inhalation Exposure
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Kim JS, Sung JH, Ji JH, Song KS, Lee JH, Kang CS, Yu IJ
- KMID: 2316998
- Saf Health Work.
- 2011 Mar;2(1):34-38.
OBJECTIVES: The antimicrobial activity of silver nanoparticles has resulted in their widespread use in many consumer products. Yet, despite their many advantages, it is also important to determine whether silver... -
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- Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder
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Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH
- KMID: 2317845
- Toxicol Res.
- 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as... -
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- Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks
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Kim MY, Kim HW, Park JH, Kim JS, Jin H, Moon SH, Eu KJ, Cho HS, Kang G, Kim YS, Kim YC, Kim HY, Lee KH, Cho MH
- KMID: 1093634
- J Vet Sci.
- 2004 Dec;5(4):379-385.
Potential toxicological interactions of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and/or dibuthyl phthalate (DBP) on ozone were investigated after 32- and 52-wk exposures using hprt mutation assay. Male and female B6C3F1 mice exposed to... -
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