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A Case of Atrial Septal Defect in Identical Twins

Lee JT, Lim HK, Choi TM, Kim SK, Kwon YJ

Atrial septal defect is one of the most common congenital heart diseases in adult, of which absolute causes is not confirmed, but explained by multifactorial inheritance. In Korea, there has...
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Familial Occurrence of Moyamoya Disease: Case Report

Jeong SR, Seo DH, Kim MS, Lee SI, Jung YT, Kim SC, Sim JH

  • KMID: 1955482
  • J Korean Neurosurg Soc.
  • 1998 Dec;27(12):1729-1733.
There is extensive evidence that moyamoya disease has a tendency for multifactorial inheritance, although the pathogenesis of moyamoya disease is not clear. The authors report a case of familial moyamoya...
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Familial Occurrence of Moyamoya Disease - Report of Two Cases -

Min SJ, Kim Y, Kim WH, Lee HK, Kim MS

  • KMID: 2256562
  • Korean J Cerebrovasc Surg.
  • 2005 Mar;7(1):75-79.
Moyamoya disease is a rare occlusive cerebrovascular disease characterized by stenosis or occlusion of the main cerebral arteries. It has a tendency for multifactorial inheritance and familial occurrence, although its...
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Febrile seizures

Chung S

Febrile seizure (FS) is the most common seizure disorder of childhood, and occurs in an age-related manner. FS are classified into simple and complex. FS has a multifactorial inheritance, suggesting...
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Molecular Genetics of Cholesterol Gallstone Disease; LITH Genes

Dong SH

  • KMID: 2168080
  • Hanyang Med Rev.
  • 2007 Feb;27(1):29-34.
Cholesterol gallstone formation is influenced by environmental and genetic factors. Cholesterol gallstone susceptible genes (Lith genes) are complex and show polygenic traits. Quantitative trait locus (QTL) analysis in inbred mice...
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Omic Approach in Non-smoker Female with Lung Squamous Cell Carcinoma Pinpoints to Germline Susceptibility and Personalized Medicine

Baldassarri M, Fallerini , Cetta F, Ghisalberti M, Bellan C, Furini S, Spiga O, Crispino S, Gotti G, Ariani F, Paladini P, Renieri A, Frullanti

PURPOSE: Lung cancer is strongly associated to tobacco smoking. However, global statistics estimate that in females the proportion of lung cancer cases that is unrelated to tobacco smoking reaches fifty...
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Pathogenesis of Type 1 Diabetes

Kim KA, Lee MS

  • KMID: 2168167
  • Hanyang Med Rev.
  • 2009 May;29(2):168-175.
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by selective destruction of pancreatic islet betacells causing insulin deficiency. T1D has been shown to be a polygenic trait,...
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