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MAO Inhibitors in Parkinson's Disease

Lee DH

  • KMID: 2065947
  • J Korean Neurol Assoc.
  • 1993 Mar;11(1):1-7.
No abstract available.
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Beyond the SSRIs

Lee MS, Nam JW

  • KMID: 2334590
  • J Korean Soc Biol Psychiatry.
  • 1999 Jul;6(1):34-40.
New antidepressants have become available for clinical use in the 1990s. Before this decade, the drugs available to treat depression consisted essentially of monoamine oxidase inhibitors, tricyclic antidepressants, and lithium....
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Monoamine Oxidase Inhibitors Attenuate Cytotoxicity of 1-Methyl-4-phenylpyridinium by Suppressing Mitochondrial Permeability Transition

Lee CS

  • KMID: 1587399
  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):207-212.
Mitochondrial permeability transition has been shown to be involved in neuronal cell death. Mitochondrial monoamine oxidase (MAO)-B is considered to play a part in the progress of nigrostriatal cell death....
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Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K

Kim JH, Son YK, Kim GH, Hwang KH

  • KMID: 1502493
  • Biomol Ther.
  • 2013 May;21(3):234-240.
Monoamine oxidase inhibitors (MAOI) have been widely used as antidepressants. Recently, there has been renewed interest in MAO inhibitors. The activity-guided fractionation of extracts from Angelica keiskei Koidzumi (A. keiskei...
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MAO-inhibitors in Parkinson's Disease

Riederer P, Laux G

Monoamine oxidase inhibitors (MAO-I) belong to the earliest drugs tried in Parkinson's disease (PD). They have been used with or without levodopa (L-DOPA). Non-selective MAO-I due to their side-effect/adverse reaction...
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Novel Pharmacological Treatment for Depression

Jeong HJ, Moon E

Development of various antidepressants such as monoamine oxidase inhibitors, tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressant has led to a tremendous...
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Characteristics of Cardiac Toxicity in Antidepressant Overdose and Its Treatment

Choi KH, Lee KU

  • KMID: 2287410
  • Korean J Psychopharmacol.
  • 2008 Dec;19(6):323-333.
The mortality and morbidity in tricyclic antidepressants (TCAs) overdose still remained high due to fatal cardiac toxicities despite their decreased prescriptions. Also, monoamine oxidase inhibitors (MAOIs) may show relatively high...
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Adverse Effects and Pharmacological Management of Newer Antidepressants: Focusing on Common but Under-Recognized Adverse Effect

Lee KK

  • KMID: 2287864
  • Korean J Psychopharmacol.
  • 2014 Jan;25(1):11-20.
Nowadays newer antidepressants are commonly used in clinical practice, since they are as effective as tricyclic antidepressant, but show less adverse effects. However there are many unexpected adverse effects of...
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Effects of Selective Serotonin Reuptake Inhibitors (SSRIs) on the Vasoconstriction of Isolated Rat Aorta

Park KS, Kong ID, Park KC, Lee JW

BACKGROUND: One of the most common side effects of antidepressant medication is orthostatic hypotension, which can be caused by impaired vasoconstriction. This study was designed to compare the inhibitory effects...
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Pharmacotherapy of Posttraumatic Stress Disorder

Bahk WM, Lee KU

  • KMID: 2286871
  • Korean J Psychopharmacol.
  • 2004 Mar;15(1):22-29.
Posttraumatic stress disorder (PTSD) is relatively common and chronic illness that causes severe functional impairment. Though many studies have been done, PTSD is still difficult to understand because of heterogeneity...
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Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (II) : Antidepressant Efficacy Compared with Placebo, Difference in Efficacy of Antidepressants, and Appropriate Time of Efficacy Judgment in Antidepressant Therapy

Sung SH, Park SC, Han KM, Won ES, Lee HY, Koo JW, Paik JW, Lee KM, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Park YC, Lee MS, Hahn SW

  • KMID: 2343633
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):372-385.
OBJECTIVES: The purpose of this study was to suggest recommendations of antidepressant efficacy compared with placebo, difference in efficacy of antidepressants, and appropriate time of efficacy judgment in antidepressant therapy. METHODS:...
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Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis

Sung KW, Kim SY, Kim ON, Lee SB

  • KMID: 1614852
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior...
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Multi Target Neuroprotective and Neurorestorative Anti-Parkinson and Anti-Alzheimer Drugs Ladostigil and M30 Derived from Rasagiline

Youdim MB

Present anti-PD and -AD drugs have limited symptomatic activity and devoid of neuroprotective and neurorestorative property that is needed for disease modifying action. The complex pathology of PD and AD...
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Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?

Chang EJ, Choi EJ, Kim KH

Tapentadol is a novel oral analgesic with a dual mode of action as an agonist of the µ-opioid receptor (MOR), and as a norepinephrine reuptake inhibitor (NRI) all in a...
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Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (III) : Dose Increment, Switching, Combination, and Augmentation Strategy in Antidepressant Therapy

Han KM, Park SC, Won ES, Sung SH, Lee H, Koo JW, Lee K, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Hahn SW, Park YC, Lee MS

  • KMID: 2343634
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):386-401.
OBJECTIVES: The aim of this study was to demonstrate the recommendations for antidepressant treatment strategy of dose increment, switching, combination, and augmentation therapy derived from Evidence-Based Korean Pharmacological Treatment Guideline...
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Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition

Won E, Park SC, Han KM, Sung SH, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Hahn SW, Park YC, Lee MS

This paper aims to introduce, summarize, and emphasize the importance of the 'Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition'. The guideline broadly covers most aspects of the...
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