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Precision surgery for cancer: a new surgical concept in individual tumor biology-based image-guided surgery

Choi N, Jeong HS

Surgery has long been a cornerstone of cancer treatment in many types of cancer. Traditionally, intraoperative assessment of the resection margin is largely dependent on visual inspection and palpation of...
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Identification of Radioactive Iodine Refractory Differentiated Thyroid Cancer

Mu ZZ, Zhang X, Lin YS

Most differentiated thyroid cancer (DTC) patients have an excellent prognosis. However, about one-third of DTC patients with recurrent or metastatic disease lose the hallmark of specific iodine uptake initially or...
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Non-invasive molecular imaging of immune cell dynamics for vaccine research

Youn H, Hong KJ

In order to develop a successful vaccine against deadly diseases with a wide range of antigenic diversity, an in-depth knowledge of the molecules and signaling mechanisms between the vaccine candidates...
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Deep-Learning-Based Molecular Imaging Biomarkers: Toward Data-Driven Theranostics

Choi H

Deep learning has been applied to various medical data. In particular, current deep learning models exhibit remarkable performance at specific tasks, sometimes offering higher accuracy than that of experts for...
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Insights into Hypoxia: Non-invasive Assessment through Imaging Modalities and Its Application in Breast Cancer

Daimiel I

Oxygen is crucial to maintain the homeostasis in aerobic cells. Hypoxia is a condition in which cells are deprived of the oxygen supply necessary for their optimum performance. Whereas oxygen...
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Use of Molecular Imaging in Clinical Drug Development: a Systematic Review

Son H, Jang K, Lee H, Kim SE, Kang KW, Lee H

BACKGROUND: Molecular imaging such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) can provide the crucial pharmacokinetic-pharmacodynamic information of a drug non-invasively at an early stage of...
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Progress of Coordination and Utilization of Zirconium-89 for Positron Emission Tomography (PET) Studies

La MT, Tran VH, Kim HK

Radiometals have been commonly used in medical applications, and utilization of such metals continues to be an attractive research area. In particular, a variety of radiometals have been developed and...
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Current Status of Theranostics in Jordan

Al-Ibraheem A, Mohamedkhair A

Exploring the unknown is one of the key factors that lead to great discoveries in mankind history.With the advances in medicine and the development of new approaches towards patient care,...
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Understanding Vulnerable Plaques: Current Status and Future Directions

Lee KY, Chang K

The main cause of acute myocardial infarction is plaque rupture accompanied by superimposed coronary thrombosis. Thin-cap fibroatheromas (TCFAs) have been suggested as a type of lesion with a vulnerability that...
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Molecular Imaging in Breast Cancer

Miladinova D

Breast cancer (BC) is themost common cancer among females withmore than 2 million new cases diagnosed worldwide in 2018. Although the prognosis in the majority of cases in the early...
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Targeted Near-Infrared Fluorescence Imaging for Regenerative Medicine

Yang C, Park GK, McDonald E, Choi HS

BACKGROUND: Advances in tissue engineering and regenerative medicine over the last three decades have made great progress in the development of diagnostic and therapeutic methodologies for damaged tissues. However, regenerative...
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Updates in molecular imaging techniques

Hyun H, Cho CS

No abstract available.
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Breast-Specific Gamma Imaging in Breast Cancer Screening

Cha ES

The sensitivity and specificity of breast cancer screening with mammography in dense breasts are very low, and increasing attention has been paid to breast density and screening in high-risk groups....
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Stem Cell Tracing Through MR Molecular Imaging

Yahyapour , Farhood B, Graily G, Rezaeyan A, Rezapoor S, Abdollahi , Cheki M, Amini P, Fallah H, Najafi M, Motevaseli E

Stem cell therapy opens a new window in medicine to overcome several diseases that remain incurable. It appears such diseases as cardiovascular disorders, brain injury, multiple sclerosis, urinary system diseases,...
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Photoacoustic microscopy: principles and biomedical applications

Liu W, Yao J

Photoacoustic microscopy (PAM) has become an increasingly popular technology for biomedical applications, providing anatomical, functional, and molecular information. In this concise review, we first introduce the basic principles and typical...
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Deep Learning in Nuclear Medicine and Molecular Imaging: Current Perspectives and Future Directions

Choi H

Recent advances in deep learning have impacted various scientific and industrial fields. Due to the rapid application of deep learning in biomedical data, molecular imaging has also started to adopt...
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The effect of near-infrared fluorescence conjugation on the anti-cancer potential of cetuximab

Yun JY, Hyun BH, Nam SY, Yun YW, Lee HJ, Lee BJ

This study investigated the anti-cancer potential of a near-infrared fluorescence (NIRF) molecule conjugated with Cetuximab (Cetuximab-NIRF) in six-week-old female BALB/c athymic (nu+/nu+) nude mice. A431 cells were cultured and injected...
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The potential theragnostic (diagnostic+therapeutic) application of exosomes in diverse biomedical fields

Kim YS, Ahn JS, Kim S, Kim HJ, Kim SH, Kang JS

Exosomes are membranous vesicles of 30-150 nm in diameter that are derived from the exocytosis of the intraluminal vesicles of many cell types including immune cells, stem cells, cardiovascular cells...
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Understanding Neurogastroenterology From Neuroimaging Perspective: A Comprehensive Review of Functional and Structural Brain Imaging in Functional Gastrointestinal Disorders

Kano M, Dupont P, Aziz Q, Fukudo S

  • KMID: 2422842
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):512-527.
  • doi: 10.5056/jnm18072
This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses...
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Influence of Androgen Deprivation Therapy on the Uptake of PSMA-Targeted Agents: Emerging Opportunities and Challenges

Bakht MK, Oh SW, Youn H, Cheon GJ, Kwak C, Kang KW

Prostate-specific membrane antigen (PSMA) is an attractive target for both diagnosis and therapy because of its high expression in the vast majority of prostate cancers. Development of small molecules for...
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