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Molecular epidemiology and characterization of Streptococcus mutans strains in Korea

Kim SY, Bae IK, Lee JH, Shin JH, Kim JB

OBJECTIVES: We investigated the characteristics of Streptococcus mutans in the national culture collection from Korea. Twenty-nine (dental plaque, n=27; endodontic infections, n=1; blood, n=1) isolates were included in this study. METHODS:...
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Colonization Prevalence and Risk Factor Analysis of Carbapenem-Resistant Acinetobacter baumannii in an Intensive Care Unit without Outbreaks

Kim YA, Park YS, Lee SS, Son YJ, Yeon JH, Seo YH, Lee K

BACKGROUND: Acinetobacter baumannii is a well-known etiologic agent of a variety of nosocomial infections; the resistance rate to imipenem is surprisingly high in Korea. The colonization of carbapenem-resistant A. baumannii...
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Molecular Epidemiologic Study of a Methicillin-resistant Staphylococcus aureus Outbreak at a Newborn Nursery and Neonatal Intensive Care Unit

Kang HM, Park KC, Lee KY, Park J, Park SH, Lee DG, Kim JH

PURPOSE: This study aimed to investigate the molecular epidemiology of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak at a newborn nursery and neonatal intensive care unit (NICU). METHODS: During the outbreak, from...
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Molecular Epidemiology of Staphylococcus aureus in Skin and Soft Tissue Infections and Bone and Joint Infections in Korean Children

Park SG, Lee HS, Park JY, Lee H

BACKGROUND: Community acquired-methicillin resistant Staphylococcus aureus (MRSA) clones, including ST1, ST8, and ST30 are reported worldwide. However, data among Korean children are limited. Thus, we investigated the molecular characteristics of...
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Molecular Prevalence and Genotypes of Cryptosporidium parvum and Giardia duodenalis in Patients with Acute Diarrhea in Korea, 2013–2016

Ma DW, Lee MR, Hong SH, Cho SH, Lee SE

Cryptosporidium parvum and Giardia duodenalis are the main diarrhea-causing parasitic pathogens; however, their prevalence in Korea is unknown. Here, we conducted a survey to determine the prevalence and genotype distribution...
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Mendelian Randomization Analysis in Observational Epidemiology

Lee K, Lim CY

Mendelian randomization (MR) in epidemiology is the use of genetic variants as instrumental variables (IVs) in non-experimental design to make causality of a modifiable exposure on an outcome or disease....
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Molecular Epidemiology of Human Astrovirus in Stool Samples From Patients With Acute Gastroenteritis in Korea, 2013–2017

Kim JS, Lee WJ, Lee SK, Lee EJ, Hyun J, Kim HS, Song W, Kim HS

BACKGROUND: Human astroviruses (HAstVs) are one of the major causes of acute gastroenteritis. Classic HAstVs can be classified into eight genotypes. We investigated the positive rate of HAstVs and the...
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An Excel Macro for Determining Allelic and Sequence Types of Bacterial Clones in Multilocus Sequence Typing

Park YJ, Choi MH, Kim D, Lee K, Kim HO, Jeong SH

BACKGROUND: Multilocus sequence typing (MLST) was designed to overcome the low discriminatory power and poor reproducibility of previous molecular typing schemes, and it is useful for inter-laboratory, inter-regional, and inter-national...
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Molecular epidemiology of sequence type 33 of Shiga toxin-producing Escherichia coli O91:H14 isolates from human patients and retail meats in Korea

Lee JB, Kim SK, Wi SM, Cho YJ, Hahn TW, Yu JY, Kim S, Hong S, Kim J, Yoon JW

Sequence type (ST) 33 of Shiga toxin-producing Escherichia coli (STEC) strain O91:H14 has been proposed as a potential domestic clone of STEC in Korea because of its high prevalence among...
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Molecular Epidemiology and Mechanisms of 43 Low-Level Linezolid-Resistant Enterococcus faecalis Strains in Chongqing, China

Hua R, Xia Y, Wu W, Yang M, Yan J

BACKGROUND: Enterococcus faecalis strains with low-level resistance to linezolid (an oxazolidinone antibiotic) have become common. No large-scale study has examined the underlying mechanisms in linezolid-resistant E. faecalis (LRE) strains. We...
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Introduction of Phylodynamics for Controlling the HIV/AIDS Epidemic in Korea

Bae JM

As over 1000 new cases of HIV/AIDS occur in Korea annually, preventive health programs against HIV/AIDS are urgently needed. Since phylodynamic studies have been suggested as a way to understand...
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First detection and genetic characterization of porcine parvovirus 7 from Korean domestic pig farms

Ouh IO, Park S, Lee JY, Song JY, Cho IS, Kim HR, Park CK

Porcine parvovirus 7 (PPV7) was first detected in Korean pig farms in 2017. The detection rate of PPV7 DNA was 24.0% (30/125) in aborted pig fetuses and 74.9% (262/350) in...
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Molecular prophage typing of Staphylococcus aureus isolates from bovine mastitis

Ko DS, Seong WJ, Kim D, Kim EK, Kim NH, Lee CY, Kim JH, Kwon HJ

Staphylococcus aureus is one of the major pathogens causing bovine mastitis and foodborne diseases associated with dairy products. To determine the genetic relationships between human and bovine or bovine isolates...
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Genetic diversity of bovine Mycobacterium avium subsp. paratuberculosis discriminated by IS1311 PCR-REA, MIRU-VNTR, and MLSSR genotyping

Park HT, Park HE, Park WB, Kim S, Hur TY, Jung YH, Yoo HS

The aim of this study was to describe the genetic diversity of Mycobacterium avium subsp. paratuberculosis (MAP) obtained from individual cows in Korea. Twelve MAP-positive fecal DNA samples and 19...
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Characterization of JAK2 V617F (1849 G > T) Mutation in Cervical Cancer Related to Human Papillomavirus and Sexually Transmitted Infections

Abdolmaleki M, Sohrabi A

BACKGROUND: Human papillomavirus (HPV) genotypes that infect the genital tract play a main etiologic role in cervical cancer progression. Other environmental factors, such as sexually transmitted diseases and the host...
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Molecular Epidemiology of Viral Conjunctivitis in the Southern Region of South Korea, 2012–2016

Park DW, Kim MJ, Kim KG, Cho SJ, Park HJ, Shin JH, Ha YD, Seo MH, Kim JH, Lee Y, Park MD, Yoon HM, Kim ES, Hong YJ, Kee H, Chung JK

Epidemic keratoconjunctivitis (EKC) and acute hemorrhagic conjunctivitis (AHC) are common diseases caused by human adenoviruses (HAdV) and enteroviruses, respectively, in South Korea. However, there are limited studies on the molecular...
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Prevalence of Escherichia coli Carrying pks Islands in Bacteremia Patients

Lee E, Lee Y

Escherichia coli can harbor genomic pks islands that code for a polyketide-peptide genotoxin known as colibactin. E. coli strains carrying pks islands trigger genetic instability. pks islands have been significantly...
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Clinical characteristics and genetic variation in respiratory syncytial virus isolated from infants hospitalized due to acute bronchiolitis in Korea during winter season 2016–2017

Yon DK, Min CY, Ha EK, Jee HM, Jung YH, Lee KS, Sheen YH, Han MY

PURPOSE: Circulating patterns of predominant respiratory syncytial virus (RSV) genotypes in the community may be helpful in understanding molecular epidemiology and predicting future outbreaks of the RSV genotype. We investigated...
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Retrospective Molecular Epidemiology Study of PD-L1 Expression in Patients with EGFR-Mutant Non-small Cell Lung Cancer

Cho JH, Zhou W, Choi YL, Sun JM, Choi H, Kim TE, Dolled-Filhart M, Emancipator K, Rutkowski , Kim J

PURPOSE: Data are limited on programmed death ligand 1 (PD-L1) expression in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: We retrospectively evaluated the relationship between...
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Serological and molecular epidemiology of Japanese encephalitis virus infections in swine herds in China, 2006–2012

Chai C, Wang Q, Cao S, Zhao Q, Wen Y, Huang X, Wen X, Yan Q, Ma X, Wu R

Japanese encephalitis virus (JEV) is a mosquito-borne, zoonotic flavivirus causing viral encephalitis in humans and reproductive disorder in swine. JEV is prevalent throughout China in human; however, spatiotemporal analysis of...
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