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Antiasthmatic effect of atorvastatin via modulation of macrophage activation

Mo Y, Bae B, Kim Y, Kang H, Lee HS, Cho SH, Kang HR

Purpose: Asthma is a chronic airway inflammatory disorder and is associated with macrophages. Statin, a well-known lipid-lowering agent, has recently been noted for its anti-inflammatory effect on macrophage. This study...
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Analysis of Risk Factors for a Poor Prognosis in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Construction of a Prognostic Composite Score

Mo Y, Wang L, Zhu L, Li F, Yu G, Luo Y, Ni M

Background and Purpose: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most-common form of autoimmune encephalitis, but its early diagnosis is challenging. This study aimed to identify the risk factors for a poor...
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Cigarette smoke extract contributes to the inception and aggravation of asthmatic inflammation by stimulating innate immunity

Kim Y, Kim J, Mo Y, Park DE, Lee HS, Jung JW, Kang HR

Purpose: Smoking is a risk factor for the development of asthma and worsens the long-term prognosis of asthma. This study investigated the effect of cigarette smoke extract (CSE) on innate...
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Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model

Mo Y, Kim Y, Bang JY, Jung J, Lee CG, Elias JA, Kang HR

Mesenchymal stem cells (MSCs) are attractive alternatives to conventional anti-asthmatic drugs for severe asthma. Mechanisms underlying the anti-asthmatic effects of MSCs have not yet been elucidated. This study evaluated the...
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Unmet needs in health training among nurses in rural Chinese township health centers: a cross-sectional hospital-based study

Mo Y, Hu G, Yi Y, Ying Y, Huang H, Huang Z, Lin J

PURPOSE: Maintaining a sufficient and competent rural nursing workforce is an important goal of the Chinese health delivery system. However, few studies have investigated the health training status or conducted...
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Therapeutic effect of atorvastatin on interleukin-13-induced lung pathology

Mo Y, Bae B, Kim J, Kim RL, Son K, Kang MJ, Lee CG, Cho SH, Kang HR

Purpose: Asthma is a common chronic lung disease, in which interleukin (IL)-13 is implicated as a central regulator of IgE synthesis, mucus hypersecretion, airway hyperresponsiveness (AHR), and fibrosis. This study...
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