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Identification of a Fibrillin-1 Gene Mutation in a Monozygotic Twin Presenting with Bilateral Juvenile-onset Ectopia Lentis

Yum HR, Kim SE, Shin SY, Park SH

No abstract available.
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Concomitant AID Expression and BCL7A Loss Associates With Accelerated Phase Progression and Imatinib Resistance in Chronic Myeloid Leukemia

Yu N, Shin S, Choi JR, Kim Y, Lee KA

No abstract available.
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L-plastin: Structure, Regulation, and Roles in Cancer Invasion and in Macrophages

Kim HJ, Lee HH

The cytoskeleton consists of 3 filamentous components: intermediate filaments, microtubules, and actin filaments. Actin filaments continuously assemble and disassemble far out of equilibrium to adapt cells in response to external...
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Autophagy Activity in Pulmonary Metastatic Tumor Tissues from Colorectal Cancer: A Pilot Study

Kim YS, Shin JH, Bae MK, Lee CY, Kim DJ, Chung KY, Lee JG

PURPOSE: Autophagy has been reported to be involved in treatment failure in tumor. We aimed to evaluate autophagy activity in tumor tissue and compare them between the recurrence and non-recurrence...
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Exuberant Smooth Muscle Cells in Fibroadenoma of the Breast: A Case Report

Kim GE, Kim Y, Jeong EH, Kim JH, Park MH, Lee JS

  • KMID: 2277583
  • Korean J Pathol.
  • 2010 Aug;44(4):431-434.
Smooth muscle cell metaplasia is an extremely rare form of stromal differentiation in fibroadenomas. We describe a case of fibroadenoma with exuberant smooth muscle cells in a 72-year-old woman. The...
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Control of ovarian primordial follicle activation

Kim JY

The ovarian follicles develop initially from primordial follicles. The majority of ovarian primordial follicles are maintained quiescently as a reserve for the reproductive life span. Only a few of them...
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Autosomal Dominant Inherited Cowden's Disease in a Family

Ha JW

Cowden's disease, also known as a kind of phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome, is an uncommon autosomal dominant inherited complex disorder with various hamartomatous growths of multiple...
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Multiorgan Involvements of Cowden Disease in a 50-Year-Old Woman: A Case Report and Literature Overview

Lee EJ, Jung WS, Ko JM, Park HJ

Cowden disease is the prototype of phosphate and, tensin homologue deleted on the chromosome 10 (PTEN) hamartoma tumor syndrome caused by germline mutations in the tumor suppressor PTEN, which is...
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A Case of Aortic Dissection with Marfan Syndrome and Ankylosing Spondylitis

Ryou JW, Park JY, Song EJ, Hur JW

  • KMID: 2142907
  • Korean J Med.
  • 2013 Jun;84(6):873-877.
A 33-year-old male presented with an acute onset of back pain and abdominal pain. He was 189.9 cm tall and had an arm span of 194 cm, and had mild...
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The Relationship between Prognostic Factors and the Expression Pattern of Fascin and E-cadherin in Renal Cell Carcinoma

Kang SH, Chae SW, Lee KB, Kim DH, Kim MK, Sohn JH

  • KMID: 2073793
  • Korean J Pathol.
  • 2009 Apr;43(2):139-144.
BACKGROUND: Fascin is associated with motility in various transformed cells. Overexpression of fascin is known to aid in the progression of some cancers and is associated with a poor prognosis....
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Attenuation of Spinal Cord Injury-Induced Astroglial and Microglial Activation by Repetitive Transcranial Magnetic Stimulation in Rats

Kim JY, Choi GS, Cho YW, Cho H, Hwang SJ, Ahn SH

Spinal cord injury (SCI) causes not only loss of sensory and motor function below the level of injury but also chronic pain, which is difficult and challenging of the treatment....
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Prognostic Significance of Fascin Expression in Stage I Non-small Cell Lung Cancer

Roh MS, Um SJ, Choi Y, Kim KN, Choi PJ, Lee SK, Son C, Yang D

  • KMID: 2319048
  • Tuberc Respir Dis.
  • 2008 Aug;65(2):105-109.
BACKGROUND: Fascin is an actin-bundling protein that plays an important role in cellular motility. Fascin is normally expressed in the neuronal and mesenchymal cells and its expression is low or...
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Independent Prognostic Value of the Fascin Expression in Patients with Esophageal Cancer

Choi PJ, Jeong SS, Bang JH, Cho KJ, Woo JS, Roh MS

  • KMID: 1987459
  • Korean J Thorac Cardiovasc Surg.
  • 2008 Feb;41(1):74-81.
Backgrond: Fascin is an actin-bundling protein that induces membrane protrusions and it increases cell motility in various transformed cells. Esophageal cancer is one of the most lethal malignancies, and it...
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Expression of calponin in periglomerular myofibroblasts of rat kidney with experimental chronic injuries

Lee SY, Choi JY, Jin DC, Kim J, Cha JH

Our previous research demonstrated that calponin-immunoreactivity was localized in myofibroblasts of the periglomerular region of human kidney specimens obtained at the time of transplantation from organ recipients. In the present...
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Preliminary Results after Reduction of DDH via Medial Approach

Bae JY, Kim DH, Cho TJ, Yoo WJ, Chung CY, Park MS, Choi IH

PURPOSE: We report the outcomes of medial open reduction for developmental dysplasia of the hip (DDH). MATERIALS AND METHODS: This study reviewed the medical records and radiographs of 33 DDH cases...
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The Prognostic Significance of Fascin Expression in Colorectal Carcinoma

Lee JM, Lee JH, Roh MS, Park KJ

BACKGROUND/AIMS: Fascin, an actin-bundling protein found in membrane ruffles, microspikes, and stress fibers, induces membrane protrusions and increases cell motility in normal and various transformed cells. The expression of fascin...
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Anti-Migration and Anti-Invasion Effects of Curcumin via Suppression of Fascin Expression in Glioblastoma Cells

Park KS, Yoon SY, Park SH, Hwang JH

BACKGROUND: The natural compound curcumin was known to inhibit migration and invasion of glioblastoma (GBM) cells. Fascin, a kind of actin-binding proteins, is correlated with migration and invasion of GBM...
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Expression of Fascin in Gallbladder Carcinoma

Na KY, Kim YH, Kim YW, Hong SW

  • KMID: 2211228
  • J Korean Surg Soc.
  • 2008 Aug;75(2):102-108.
PURPOSE: Gallbladder carcinoma is the most common malignancy of the biliary tract in Koreans. However the exact histopathological characteristics and its carcinogenesis are not well understood. Fascin is an actin...
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Cancer stem cell theory and update in oral squamous cell carcinoma

Kim DH, Yun JY, Lee JH, Myoung H, Kim SM

Cancer stem cells have stem cell-like features, such as the ability for self-renewal and differentiation but show unlimited growth because they have the lost normal regulation of cell growth. Cancer...
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Correlation between the Expression Reduction of Insulin-like Growth Factor Binding Protein (IGFBP)-3 and PTEN and the Clinicopathological Parameters in Breast Cancer

Jung SH, Youn HJ, Kim MS, Kim SY, Hwang PH, Lee DY

PURPOSE: Insulin-like growth factor binding protein (IGFBP-3) and phosphatase and tensin homolog (PTEN) are tumor-suppressor genes that may be involved in breast tumorigenesis. However, the roles of these genes in...
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