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Emerging Neural Stimulation Technologies for Bladder Dysfunctions

Lee JW, Kim D, Yoo S, Lee H, Lee GH, Nam Y

In the neural engineering field, physiological dysfunctions are approached by identifying the target nerves and providing artificial stimulation to restore the function. Neural stimulation and recording technologies play a central...
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Measurement of Bladder Volume Using an Implantable Volume Sensor in Rats

Lee DS, Kim SJ, Sohn DW, Yoo JM, Choi BK, Lee MK, Lee SJ, Kim SW

  • KMID: 2298752
  • Korean J Androl.
  • 2010 Dec;28(3):169-174.
PURPOSE: Real-time monitoring of urinary bladder volume can not only provide information on urinary bladder function more precisely in laboratories and in the setting of intravesical pressure monitoring, but can...
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Waveform Sorting of Rabbit Retinal Ganglion Cell Activity Recorded with Multielectrode Array

Jin GH, Lee TS, Goo YS

  • KMID: 2080301
  • Korean J Med Phys.
  • 2005 Sep;16(3):148-154.
Since the output of retina for visual stimulus is carried by neurons of very diverse functional properties, it is not adequate to use conventional single electrode for recording the retinal...
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Effects of Bupivacaine on the Membrane Potential and Intracellular Na

Joo CU, Kim WH, Ko JK, Lee SK, Chae SW

BACKGROUND: Bupivacaine is a potent, and commonly used, long acting local anesthetic. If accidentally injected into the systemic circulation, bupivacaine can cause lethal dysrhythmias and circulatory collapse. Attempts to treat...
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Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood

Lee H, Ugay D, Hong S, Kim Y

Alzheimer's disease (AD) is pathologically characterized by a long progressive phase of neuronal changes, including accumulation of extracellular amyloid-β (Aβ) and intracellular neurofibrillary tangles, before the onset of observable symptoms....
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Effects of Cisapride on Action Potential Duration and on ATP-Sensitive K Channel in Guinea Pig Ventricular Muscles

Joo CU, Kim YJ, Mun SK, Chae SW

  • KMID: 1748178
  • J Korean Pediatr Soc.
  • 1999 Jul;42(7):953-958.
PURPOSE: Cisapride(Prepulsid(R)) has been recently associated with long QT syndrome. It has been reported to cause Torsades de Pointes and induce early afterdepolarization in rabbit Purkinje fibers. We investigated the...
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Influence of Hypoglycemia and Hypothermia on Direct Current Potential During Cortical Spreading Depression in Rats

Moon SH, Park JY, Park YK, Lee KC, Chu CW, Lee HK

  • KMID: 2019572
  • J Korean Neurosurg Soc.
  • 1994 Jul;23(7):783-790.
The object of this study was to investigate the influences of hypoglycemia and hypothermia on the direct current(DC) pontetial changes during cortical spreading depression(CSD) in rats. The induction of CSD...
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Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats

Salazar BH, Hoffman KA, Zhang C, Kavanagh A, Zhang Y, Boone TB, Munoz A

PURPOSE: To simultaneously monitor electrical discharges in various bladder regions and the external urethral sphincter (EUS) during voiding contractions, and to assess the functional role of myogenic modulation of the...
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Electrophysiological Characteristics of Arterially-Perfused Canine Pulmonary Veins: Role of the Delayed Afterdepolarization-Induced Triggered Activity

Nam GB, Choi KJ, Park DW, Kim J, Rhee KS, Kim YH

BACKGROUND AND OBJECTIVES: The mechanism responsible for the generation of ectopic beats in pulmonary veins (PVs) remains to be well defined. The present study examines the electrophysiological characteristics of the...
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Carbon-Fiber Based Microelectrode Array Embedded with a Biodegradable Silk Support for In Vivo Neural Recording

Lee Y, Kong C, Chang JW, Jun SB

BACKGROUND: Recently, carbon fibers have been utilized to develop a depth-type microelectrode array for chronic neural recording. Since the diameter of carbon fibers is smaller than the conventional electrodes made...
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Temporal changes in neuronal activity of the bilateral medial vestibular nuclei following unilateral labyrinthectomy in rats

Park BR, Lee MY, Kim MS, Lee SH, Na HJ, Doh NY

  • KMID: 2071549
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):481-490.
To investigate the changes in the responses of vestibular neurons with time during vestibular compensation, the resting activity and dynamic responses of type I and II neurons in the medial vestibular nuclei...
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Characterization of Tetrodes Coated with Au Nanoparticles (AuNPs) and PEDOT and Their Application to Thalamic Neural Signal Detection in vivo

Lee D, Moon HC, Tran BT, Kwon DH, Kim YH, Jung SD, Joo JH, Park YS

Tetrodes, consisting of four twisted micro-wires can simultaneously record the number of neurons in the brain. To improve the quality of neuronal activity detection, the tetrode tips should be modified...
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Effects of Hyperosmolar Solution on the Twitch Force, Membrane Potential, and Intracellular Sodium Activity in Purkinje Fibers and Ventricular Muscles

Kim JS, Gho JK, Joo CU, Chae SW

BACKGROUND: Hypertonic solutions are using in emergency patients including refractory shock. The effects of the hyperosmotic solutions for the cardiac contractile effect has remained unclear. To study the mechanism of...
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Characteristics of Motor Evoked Potentials by Pyramidal and Extrapyramidal Systems in Rats

Kim SS, Shim YS, Shim DM, Kim TG, Ha DH, Song HH, Song JY, Park BR, Kim JH

  • KMID: 2199170
  • J Korean Orthop Res Soc.
  • 1999 Apr;2(1):41-50.
PURPOSE: Electrophysiologically assess conduction pathways of the pyramidal and extrapyramidal systems in rats and predict the pathways involved in spinal cord injuries. METHOD: The motor area of the cerebral cortex, medullary...
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Effects of Noxious Peripheral Nerve Stimulation on the Activity of Respiratory Neurons in the Ventrolateral Medulla of Cats

Kim CJ, Kim SJ, Goo YS, Kim J, Choi KS

  • KMID: 1692126
  • J Korean Neurosurg Soc.
  • 1993 Mar;22(3):419-430.
Noxious peripheral nerve stimulation causes changes of arterial blood pressure by way of somatosympathetic reflex, and may play an important role in determining the periodicity of respiratory neurons at the...
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Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

Jin ST, Lee MK, Ghang JY, Jeon SM

  • KMID: 2339949
  • J Korean Neurosurg Soc.
  • 2012 Sep;52(3):261-263.
The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical...
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Effect of the K+ Channel Modulations on Glutamate and K+ Concentrations in Rabbit Hippocampus during Transient Global Ischemia

Choi KT, Cho MW, Suh BT, Lee JR, Park HS, Ryu PD

BACKGROUND: Cerebral ischemia causes an increase in extracellular potassium ([K+]e) through activation of the KATP channel. This increase in [K+]e could result in neuronal depolarization and a reversal of the...
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Influence of Propofol and Fentanyl on Deep Brain Stimulation of the Subthalamic Nucleus

Kim W, Song IH, Lim YH, Kim MR, Kim YE, Hwang JH, Kim IK, Song SW, Kim JW, Lee WW, Kim HJ, Kim C, Kim HC, Kim IY, Park HP, Kim DG, Jeon BS, Paek SH

We investigated the effect of propofol and fentanyl on microelectrode recording (MER) and its clinical applicability during subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. We analyzed 8 patients with...
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Magnetic Resonance Image Guided Unilateral Pallidotomy for Parkinson's Disease; Surgical Technique and Clinical Efficacy

Kim YS

  • KMID: 2018572
  • J Korean Neurosurg Soc.
  • 2002 Jun;31(6):545-550.
OBJECTIVE: The authors present a clinical analysis to determine the clinical efficacy of unilateral palliotomy for Parkinson's disease without microelectrode recording procedure and to review the surgical technique, based on...
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Myocardial Depressant Effects of Sevoflurane: A comparative Study with Isoflurane on Mechanical and Electrophysiologic Effects In Vitro

Park WK, Suh CK

Dose-related depression of left ventricular function or cardiac output has been reported in humans and in vivo animal studies with sevoflurane (SEVO) anesthesia and myocardial depressant effect of SEVO appeared...
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