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Resolution of Recalcitrant Uveitic Optic Disc Edema Following Administration of Methotrexate: Two Case Reports

Woo SJ, Kim MJ, Park KH, Lee YJ, Hwang JM

A 13-year-old male and a 15-year-old female presented with optic disc edema associated with chronic recurrent uveitis. While the ocular inflammation responded to high doses of oral prednisolone, the disc...
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Successful Combination Therapy of Cyclosporine and Methotrexate for Refractory Polymyositis with Anti-Jo-1 Antibody: A Case Report

Chang HK, Lee DH

Although corticosteroids have been the initial agent for the treatment of inflammatory myopathies (IM), immunosuppressive agents such as azathioprine, methotrexate, cyclophosphamide, or cyclosporine are commonly required to control the disease...
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Predictors of Success of Repeated Injections of Single-dose Methotrexate Regimen for Tubal Ectopic Pregnancy

Cho GJ, Lee SH, Shin JW, Lee NW, Kim T, Kim HJ, Lee KW

The purpose of this study is to evaluate predictors of success of repeated injections of methotrexate in the single-dose regimen for the treatment of tubal ectopic pregnancy. All patients who...
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Survival improvement with combined radio-chemotherapy in the primary central nervous system lymphomas

Wu HG, Kim IH, Ha SW, Park CI, Bang YJ, Huh DS

The benefits of radio-chemotherapy in HIV-negative primary central nervous system (CNS) lymphomas were analyzed in 40 patients, who received radiotherapy to the brain or craniospinal axis with the total dose...
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Pathological responses to preoperative high-dose methotrexate chemotherapy in osteosarcoma: experience in Korea cancer hospital

Lee SY, Jeon DG, Kim SS, Jang JJ, Cho KJ

During the last decade, many clinical investigators at various cancer centers have reported the efficacy of various chemotherapeutic agents in the treatment of osteosarcoma. The regimens using high-dose methotrexate (HDMTX)...
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Long-Term Survivals of Stage IIB Osteosarcoma: A 20-Year Experience in a Single Institution

Cho Y, Jung GH, Chung SH, Kim JY, Choi Y, Kim JD

BACKGROUND: The purpose of this study is to evaluate the disease-free survival (DFS) and overall survival (OS) of patients with stage IIB osteosarcoma at a single institution for 20 years...
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Clinical Outcomes of Low-Dose Methotrexate Therapy as a Second-Line Drug for Intravenous Immunoglobulin-Resistant Kawasaki Disease

Jang H, Kim KY, Kim DS

PURPOSE: Intravenous immunoglobulin (IVIG) is the standard treatment for Kawasaki disease (KD). However, there is still no standard treatment for IVIG-resistant KD. This study aimed to evaluate the efficacy of...
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A case of pancytopenia secondary to low-dose pulse methotrexate therapy in a patient with rheumatoid arthritis and renal insufficiency

Park GT, Jeon DW, Roh KH, Mun HS, Lee CH, Park CH, Kang KW, Kim SM, Kang JM, Park HC

  • KMID: 759089
  • Korean J Intern Med.
  • 1999 Jan;14(1):85-87.
Most reports on serious MTX toxicity have focused on hepatic abnormalities, while other effects, including hematologic reactions, have not been emphasized. We experienced a case of pancytopenia secondary...
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Low-dose Methotrexate Therapy for Intravenous Immunoglobulin-resistant Kawasaki Disease

Lee TJ, Kim KH, Chun JK, Kim DS

PURPOSE: The aim of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) as a treatment for patients with Kawasaki disease (KD) which was resistant to intravenous...
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