- Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
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Oh TJ, Shin JY, Kang GH, Park KS, Cho YM
- KMID: 2154249
- Exp Mol Med.
- 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha... -
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- Guanylyl cyclase C and guanylin reduce fat droplet accumulation in cattle mesenteric adipose tissue
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Yasuda M, Kawabata J, Akieda-Asai S, Nasu T, Date Y
- KMID: 2412452
- J Vet Sci.
- 2017 Sep;18(3):341-348.
- doi: 10.4142/jvs.2017.18.3.341
Guanylyl cyclase C (GC-C) is a member of a family of enzymes that metabolize GTP to cGMP and was first identified as a receptor for heat-stable enterotoxin. Guanylin (GNY) has... -
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- Insulin-dependent suppression of cholesterol 7alpha-hydroxlase is a possible link between glucose and cholesterol metabolisms
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Park WH, Pak YK
- KMID: 1123369
- Exp Mol Med.
- 2011 Oct;43(10):571-579.
- doi: 10.3858/emm.2011.43.10.064
Cholesterol 7alpha-hydroxylase (CYP7A1) regulates the balance between cholesterol supply and metabolism by catalyzing the rate-limiting step of bile acid biosynthesis. The transcriptional activity of CYP7A1 is tightly controlled by various... -
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- Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes
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An S, Jang YS, Park JS, Kwon BM, Paik YK, Jeong TS
- KMID: 1094120
- Exp Mol Med.
- 2008 Aug;40(4):407-417.
- doi: 10.3858/emm.2008.40.4.407
We investigated the mechanism of spontaneous cholesterol efflux induced by acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibition, and how an alteration of cholesterol metabolism in macrophages impacts on that in HepG2 cells.... -
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- Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice
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Liu HY, Chung CY, Yang WC, Liang CL, Wang CY, Chang CY, Chang CL
- KMID: 1389763
- J Vet Sci.
- 2012 Sep;13(3):245-252.
- doi: 10.4142/jvs.2012.13.3.245
The incidence of diabetes mellitus is increasing among companion animals. This disease has similar characteristics in both humans and animals. Diabetes is frequently identified as an independent risk factor for... -
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- Effect of Inslulin Administration on the Physical Performance of Rats and Mice
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Lee WK, Park HK, Hong SI, Kang DH
- KMID: 2439769
- Yonsei Med J.
- 1973 Dec;14(1):10-17.
The correlation between muscle glycogen content and physical performance in mice was evaluated by investigating whether an increase in glycogen content in skeletal muscle with insulin administration can improve the... -
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- Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
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Soliman MM, El-Senosi , Salem MM, Hamid OM, Kazuhiro K
- KMID: 1726918
- J Vet Sci.
- 2009 Sep;10(3):197-201.
- doi: 10.4142/jvs.2009.10.3.197
Treatment of AIDS (HIV) and hepatitis C virus needs protease inhibitors (PI) to prevent viral replication. Uses of PI in therapy are usually associated with a decrease in body weight... -
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- Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes
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Kim KS, Oh DH, Kim JY, Lee BG, You JS, Chang KJ, Chung H, Yoo MC, Yang HI, Kang JH, Hwang YC, Ahn KJ, Chung HY, Jeong IK
- KMID: 1401758
- Exp Mol Med.
- 2012 Nov;44(11):665-673.
This study aimed to determine whether taurine supplementation improves metabolic disturbances and diabetic complications in an animal model for type 2 diabetes. We investigated whether taurine has therapeutic effects on... -
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- The impact of pegylated interferon and ribavirin combination treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients
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Jung HJ, Kim YS, Kim SG, Lee YN, Jeong SW, Jang JY, Lee SH, Kim HS, Kim BS
- KMID: 1737597
- Clin Mol Hepatol.
- 2014 Mar;20(1):38-46.
- doi: 10.3350/cmh.2014.20.1.38
BACKGROUND/AIMS: Lipid profile and insulin resistance (IR) are associated with hepatitis C virus (HCV) and may predict the chronic hepatitis C (CHC) treatment response. The aim of this study was... -
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