- Lipid rafts are important for the association of RANK and TRAF6
-
Ha H, Kwak HB, Le SW, Kim HH, Lee ZH
- KMID: 1109317
- Exp Mol Med.
- 2003 Aug;35(4):279-284.
Rafts, cholesterol- and sphingolipid-rich membrane microdomains, have been shown to play an important role in immune cell activation. More recently rafts were implicated in the signal transduction by members of... -
- CITED
-
- Close
- SHARE
-
- Close
- GD3 Accumulation in Cell Surface Lipid Rafts Prior to Mitochondrial Targeting Contributes to Amyloid-beta-induced Apoptosis
-
Kim JK, Kim SH, Cho HY, Shin HS, Sung HR, Jung JR, Quan ML, Jiang DH, Bae HR
- KMID: 2157855
- J Korean Med Sci.
- 2010 Oct;25(10):1492-1498.
- doi: 10.3346/jkms.2010.25.10.1492
Neuronal apoptosis induced by amyloid beta-peptide (A beta) plays an important role in the pathophysiology of Alzheimer's disease (AD). However, the molecular mechanism underlying A beta-induced apoptosis remains undetermined. The... -
- CITED
-
- Close
- SHARE
-
- Close
- Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts
-
Kim BW, Choo HJ, Lee JW, Kim JH, Ko YG
- KMID: 1123769
- Exp Mol Med.
- 2004 Oct;36(5):476-485.
Mitochondrial biogenesis is known to accompany adipogenesis to complement ATP and acetyl-CoA required for lipogenesis. Here, we demonstrated that mitochondrial proteins such as ATP synthase alpha and beta, and cytochrome... -
- CITED
-
- Close
- SHARE
-
- Close
- Lipid Raft Integrity Is Required for Survival of Triple Negative Breast Cancer Cells
-
Badana A, Chintala M, Varikuti G, Pudi N, Kumari S, Kappala VR, Malla RR
- KMID: 2362923
- J Breast Cancer.
- 2016 Dec;19(4):372-384.
- doi: 10.4048/jbc.2016.19.4.372
PURPOSE: Lipid rafts are cholesterol enriched microdomains that colocalize signaling pathways involved in cell proliferation, metastasis, and angiogenesis. We examined the effect of methyl-β-cyclodextrin (MβCD)-mediated cholesterol extraction on the proliferation,... -
- CITED
-
- Close
- SHARE
-
- Close
- Cholesterol, a Major Component of Caveolae, Down-regulates Matrix Metalloproteinase-1 Expression through ERK/JNK Pathway in Cultured Human Dermal Fibroblasts
-
Kim S, Han J, Lee DH, Cho KH, Kim KH, Chung JH
- KMID: 2266173
- Ann Dermatol.
- 2010 Nov;22(4):379-388.
- doi: 10.5021/ad.2010.22.4.379
BACKGROUND: Cholesterol is a major component of specialized membrane microdomains known as lipid rafts or caveolae, which modulate the fluidity of biological membranes. Membrane cholesterol therefore plays an important role... -
- CITED
-
- Close
- SHARE
-
- Close
- CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta
-
Oh KI, Kim BK, Ban YL, Choi EY, Jung KC, Lee IS, Park SH
- KMID: 1094658
- Exp Mol Med.
- 2007 Apr;39(2):176-184.
We investigated the co-stimulatory role of a cell-surface protein, CD99. Co-ligation of CD99 and suboptimal CD3 induced T-cell activation to a level comparable to that obtained with optimal CD3 or... -
- CITED
-
- Close
- SHARE
-
- Close
