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The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism

Roy S, Dasgupta A

BACKGROUND: Metabolic dysfunctions characteristic of overt hypothyroidism (OH) start at the early stage of subclinical hypothyroidism (SCH). Na⁺/K⁺-ATPase (the sodium pump) is a transmembrane enzyme that plays a vital role...
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Effects of Chlorhexidine Digluconate on Rotational Rate of n- (9-Anthroyloxy) stearic Acid in Porphyromonas ginginvalis Outer Membranes

Jang HO, Cha SK, Lee C, Choi MG, Huh SR, Shin SH, Chung IK, Yun I

  • KMID: 2071586
  • Korean J Physiol Pharmacol.
  • 2003 Jun;7(3):125-130.
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n- (9-anthroyloxy) stearic acid was used...
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Effects of Chlorhexidine digluconate on Rotational Rate of n- (9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes

Jang HO, Kim DW, Kim BI, Sim HG, Lee YH, Lee JH, Bae JH, Bae MK, Kwon TH, Yun I

  • KMID: 1611230
  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):83-88.
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids...
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The Effect of Methanol on the Structural Parameters of Neuronal Membrane Lipid Bilayers

Joo HJ, Ahn SH, Lee HR, Jung SW, Choi CW, Kim MS, Bae MK, Chung IK, Bae SK, Jang HO, Yun I

The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane...
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The Effect of Lidocaine.HCl on the Fluidity of Native and Model Membrane Lipid Bilayers

Park JS, Jung TS, Noh YH, Kim WS, Park WI, Kim YS, Chung IK, Sohn UD, Bae SK, Bae MK, Jang HO, Yun I

The purpose of this study is to investigated the mechanism of pharmacological action of local anesthetic and provide the basic information about the development of new effective local anesthetics. Fluorescent...
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Effect of lidocaine cntdot HCl on microviscosity of phosphatidylcholine model membrane.

Chung IK, Kim IS, Choi CH, Cho GJ, Kim JB, Son WS, Jang HO, Yun I

  • KMID: 1580811
  • Korean J Physiol Pharmacol.
  • 2000 Jun;4(3):243-251.
In order to provide a basis for studying the molecular mechanism of pharmacological action of local anesthetics and to develop a fluorescence spectroscopic method which can detect the microviscosity of native and model...
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Mechanisms of Selective Antimicrobial Activity of Gaegurin 4

Kim H, Lee BJ, Lee MH, Hong SG, Ryu PD

Gaegurin 4 (GGN4), an antimicrobial peptide isolated from a Korean frog, is five times more potent against Gram-positive than Gram-negative bacteria, but has little hemolytic activity. To understand the mechanism...
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The Relationship between Lipid Peroxidation of Red Blood Cell Membrane, and Mean Corpuscular Volume and Liver Enzyme Markers in Alcohol Dependence Patients

Jeong SY, Choi IG, Suh GH, Kang HJ

  • KMID: 2334573
  • J Korean Soc Biol Psychiatry.
  • 1998 Nov;5(2):235-242.
OBJECTIVES: Alcohol-induced oxidative stress has been known to injure various tissues or organs. This stress is related with free radicals which are produced as the result of long-term alcohol consumption....
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Extracellular Vesicles in Neurodegenerative Diseases: A Double-Edged Sword

Lee JY, Kim HS

Extracellular vesicles (EVs), a heterogenous group of membrane-bound particles, are virtually secreted by all cells and play important roles in cell-cell communication. Loaded with proteins, mRNAs, non-coding RNAs and membrane...
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Bricks and mortar of the epidermal barrier

Nemes Z, Steinert P

  • KMID: 755021
  • Exp Mol Med.
  • 1999 Mar;31(1):5-19.
A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and the environment is constantly maintained by reproduction...
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