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Expresion of Collagenase-3 (Matrix Metalloproteinase-13) in human middle ear cholesteatoma and granulation

Chi J, Park JY, Kim J, Rho YS, Lim HJ

  • KMID: 2275664
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jun;44(6):572-575.
INTRODUCTION: Middle ear cholesteatoma is notorious for its capacity to absorb surrounding bone, but the exact mechanism of bone destruction is not fully understood until now. Recently, a group of...
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Immunohistochemical Study of Collagenase-3(Matrix Metalloproteinase-13) in Squamous Cell Carcinomas of the Head and Neck

Rho YS, Song BC, Park IS, Lim HJ, Kim DH

  • KMID: 2275851
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Jan;45(1):62-68.
BACKGROUND AND OBJECTIVES: Squamous cell carcinomas (SCCs) of the head and neck are known for their aggresive growth and propensity to metastasize, which often results in poor prognosis. Tumor cell...
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The Increased Expression of Matrix Metalloproteinases Associated with Elastin Degradation and Fibrosis of the Ligamentum Flavum in Patients with Lumbar Spinal Stenosis

Park JB, Kong CG, Suhl KH, Chang ED, Riew KD

BACKGROUND: One of the characteristics of spinal stenosis is elastin degradation and fibrosis of the extracellular matrix of the ligamentum flavum. However, there have been no investigations to determine which...
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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes

Choi CH, Kim TH, Sung YK, Choi CB, Na YI, Yoo H, Jun JB

BACKGROUND/AIMS: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this...
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Dermal Proliferative Effect and Safety of Automicroneedle Therapy System (AMTS)

Kim JH, Park HY, Jung M, Choi EH

  • KMID: 2301806
  • Korean J Dermatol.
  • 2010 Nov;48(11):955-965.
BACKGROUND: Various topical cosmeceuticals and lasers have been used to treat photo-aged skin that has wrinkles, acne scars and dilated pores. The microneedle therapy system (MTS) that mechanically makes multiple...
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Topical or oral treatment of peach flower extract attenuates UV-induced epidermal thickening, matrix metalloproteinase-13 expression and pro-inflammatory cytokine production in hairless mice skin

Kwak CS, Yang J, Shin CY, Chung JH

BACKGROUND/OBJECTIVES: Ultraviolet radiation (UV) is a major cause of skin photoaging. Previous studies reported that ethanol extract (PET) of Prunus persica (L.) Batsch flowers (PPF, peach flowers) and its subfractions,...
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Inhibition of MMP-13 mRNA expression by ginseng saponin in fetal rat calvarial cells

Kim YY, Ciu DZ, Kim YJ

There is a potential role of collagenase-3 in alveolar bone loss and periodontal disease progression, we need to develope or find chemotherapeutic drugs or herbal agents which may regulate the...
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Resveratrol Has Anabolic Effects on Disc Degeneration in a Rabbit Model

Kwon YJ

This study was done to evaluate whether injections of resveratrol, a natural compound found in the skin of grapes, had anabolic effects on degenerated intervertebral discs in a rabbit model....
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Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits

Chen B, Qin J, Wang H, Magdalou J, Chen L

The study investigated the effects of adenovirus-mediated gene transfection of basic fibroblast growth factor (bFGF), bFGF combined with interleukin-1 receptor antagonist protein (IL-Ra) and/or insulin-like growth factor-1 (IGF-1) both in...
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Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis

Woo YJ, Joo YB, Jung YO, Ju JH, Cho ML, Oh HJ, Jhun JY, Park MK, Park JS, Kang CM, Sung MS, Park SH, Kim HY, Min JK

Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is considered one of the pathophysiological factors in the progression...
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