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A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of ENCODE/Broad ChromHMM Annotations: A Computational Perspective

Park HS

The non-coding DNA in eukaryotic genomes encodes a language which programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this short report was to determine the...
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A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of Roadmap Genomics ChromHMM Annotations: A Computational Perspective

Park HS

The non-coding DNA in eukaryotic genomes encodes a language that programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this study was to determine the effect...
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A Statistical Analysis of SNPs, In-Dels, and Their Flanking Sequences in Human Genomic Regions

Shin SW, Kim YJ, Kim BD

  • KMID: 2166258
  • Genomics Inform.
  • 2007 Jun;5(2):68-76.
Due to the increasing interest in SNPs and mutational hot spots for disease traits, it is becoming more important to define and understand the relationship between SNPs and their flanking...
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Cost-Effectiveness of Early Surgical or Medical Therapy for Primary Open-Angle Glaucoma: A Decision Analytic Model

Lee KW, Park CK, Moon JI

  • KMID: 2125566
  • J Korean Ophthalmol Soc.
  • 2003 Jul;44(7):1543-1550.
PURPOSE: To estimate the cost-effectiveness of treatment with early surgical therapy for primary open-angle glaucoma compared with early medical therapy. METHODS: The hypothetical patient was treated with early surgical or...
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Economic Evaluation of Different Initial Treatments for Primary Open Angle Glaucoma: A Markov Model

Kwag TY, Kwag JH, Kim YD, Yim HB, Paik HJ, Park CJ, Abdul Majid ASB, Kang KD

PURPOSE: To perform an economic evaluation of the different treatment methods available for primary open-angle glaucoma in a Korean setting, including medication, selective laser trabeculoplasty, or surgery. METHODS: Three independent Markov...
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Natural History of Treated New-Onset Epilepsy in Children: A Long-term Follow-up Cohort Study in a Single Center

Shin WS, Choi IR, Chang YJ, Lee HY, Shin SS, Kim SH

  • KMID: 1441228
  • J Korean Child Neurol Soc.
  • 2012 Jun;20(2):98-107.
PURPOSE: Seizure outcomes are more complicated in terms of repeated remission and relapse in the course of epilepsy. We aim to investigate the different patterns of evolution in new-onset pediatric...
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Cost-Utility Analysis of Screening Strategies for Diabetic Retinopathy in Korea

Kim SW, Kang GW

This study involved a cost-utility analysis of early diagnosis and treatment of diabetic retinopathy depending on the screening strategy used. The four screening strategies evaluated were no screening, opportunistic examination,...
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Network meta-analysis: application and practice using R software

Shim SR, Kim SJ, Lee J, Rücker G

The objective of this study is to describe the general approaches to network meta-analysis that are available for quantitative data synthesis using R software. We conducted a network meta-analysis using...
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Survival Analysis of Gastric Cancer Patients with Incomplete Data

Moghimbeigi A, Tapak L, Roshanaei , Mahjub H

PURPOSE: Survival analysis of gastric cancer patients requires knowledge about factors that affect survival time. This paper attempted to analyze the survival of patients with incomplete registered data by using...
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Identifying Copy Number Variants under Selection in Geographically Structured Populations Based on F-statistics

Song HH, Hu HJ, Seok IH, Chung YJ

Large-scale copy number variants (CNVs) in the human provide the raw material for delineating population differences, as natural selection may have affected at least some of the CNVs thus far...
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Cost-Effectiveness of Rate- and Rhythm-Control Drugs for Treating Atrial Fibrillation in Korea

Kim M, Kim W, Kim C, Joung B

PURPOSE: Although the economic and mortality burden of atrial fibrillation (AF) is substantial, it remains unclear which treatment strategies for rate and rhythm control are most cost-effective. Consequently, economic factors...
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An Evaluative Analysis of the Referral System for Insurance Patients

Han D, Kim B, Lee Y, Bae S, Kwon S

  • KMID: 1983267
  • Korean J Prev Med.
  • 1991 Dec;24(4):485-495.
This study examined the effects of referral requirements for insurance patients which have been enforced since July 1, 1989 when medical insurance coverage was extended to the whole population except...
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Cost-effectiveness of para-aortic lymphadenectomy before chemoradiotherapy in locally advanced cervical cancer

Lee JY, Kim Y, Lee TJ, Jeon YW, Kim K, Chung HH, Kim HJ, Park SM, Kim JW

OBJECTIVE: To evaluate the cost-effectiveness of nodal staging surgery before chemoradiotherapy (CRT) for locally advanced cervical cancer in the era of positron emission tomography/computed tomography (PET/CT). METHODS: A modified Markov model...
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